17,269 research outputs found
Examining social media live stream’s influence on the consumer decision-making: a thematic analysis
oai:repository.uel.ac.uk:8x4q4Social media live streaming, in the form of live video and user stories, is widely used by influencers, organisations and individuals to connect with their audiences. Its popularity is well-established in a range of theoretical and managerial contexts. However, there is a lack of scholarship on the role of this phenomenon on consumer decision-making. Filling this gap in the research is essential due to the importance of consumer decision-making in marketing and brand strategy development in organisations. Therefore, the purpose of this paper is to explore and outline the nature of the influence of live stream on the consumer decision-making. The study was part of a 12-month Netnography consisting of participant observation and social media monitoring of brand pages and branded hashtags on social media platforms, Facebook, YouTube, Twitter and Instagram. A thematic analysis revealed five main themes and a conceptual model is proposed which outlines the social media live stream’s influence on consumer decision-making at each stage
Field-guided proton acceleration at reconnecting X-points in flares
An explicitly energy-conserving full orbit code CUEBIT, developed originally
to describe energetic particle effects in laboratory fusion experiments, has
been applied to the problem of proton acceleration in solar flares. The model
fields are obtained from solutions of the linearised MHD equations for
reconnecting modes at an X-type neutral point, with the additional ingredient
of a longitudinal magnetic field component. To accelerate protons to the
highest observed energies on flare timescales, it is necessary to invoke
anomalous resistivity in the MHD solution. It is shown that the addition of a
longitudinal field component greatly increases the efficiency of ion
acceleration, essentially because it greatly reduces the magnitude of drift
motions away from the vicinity of the X-point, where the accelerating component
of the electric field is largest. Using plasma parameters consistent with flare
observations, we obtain proton distributions extending up to gamma-ray-emitting
energies (>1MeV). In some cases the energy distributions exhibit a bump-on-tail
in the MeV range. In general, the shape of the distribution is sensitive to the
model parameters.Comment: 14 pages, 4 figures, accepted for publication in Solar Physic
Electron Inertial Effects on Rapid Energy Redistribution at Magnetic X-points
The evolution of non-potential perturbations to a current-free magnetic
X-point configuration is studied, taking into account electron inertial effects
as well as resistivity. Electron inertia is shown to have a negligible effect
on the evolution of the system whenever the collisionless skin depth is less
than the resistive scale length. Non-potential magnetic field energy in this
resistive MHD limit initially reaches equipartition with flow energy, in
accordance with ideal MHD, and is then dissipated extremely rapidly, on an
Alfvenic timescale that is essentially independent of Lundquist number. In
agreement with resistive MHD results obtained by previous authors, the magnetic
field energy and kinetic energy are then observed to decay on a longer
timescale and exhibit oscillatory behavior, reflecting the existence of
discrete normal modes with finite real frequency. When the collisionless skin
depth exceeds the resistive scale length, the system again evolves initially
according to ideal MHD. At the end of this ideal phase, the field energy decays
typically on an Alfvenic timescale, while the kinetic energy (which is equally
partitioned between ions and electrons in this case) is dissipated on the
electron collision timescale. The oscillatory decay in the energy observed in
the resistive case is absent, but short wavelength structures appear in the
field and velocity profiles, suggesting the possibility of particle
acceleration in oppositely-directed current channels. The model provides a
possible framework for interpreting observations of energy release and particle
acceleration on timescales down to less than a second in the impulsive phase of
solar flares.Comment: 30 pages, 8 figure
A theoretical investigation of the effect of proliferation & adhesion on monoclonal conversion in the colonic crypt
The surface epithelium lining the intestinal tract renews itself rapidly by a coordinated programme of cell proliferation, migration and differentiation events that is initiated in the crypts of LieberkĂĽhn. It is generally believed that colorectal cancer arises due to mutations that disrupt the normal cellular dynamics of the crypts. Using a spatially structured cell-based model of a colonic crypt, we investigate the likelihood that the progeny of a mutated cell will dominate, or be sloughed out of, a crypt. Our approach is to perform multiple simulations, varying the spatial location of the initial mutation, and the proliferative and adhesive properties of the mutant cells, to obtain statistical distributions for the probability of their domination. Our simulations lead us to make a number of predictions. The process of monoclonal conversion always occurs, and does not require that the cell which initially gave rise to the population remains in the crypt. Mutations occurring more than one to two cells from the base of the crypt are unlikely to become the dominant clone. The probability of a mutant clone persisting in the crypt is sensitive to dysregulation of adhesion. By comparing simulation results with those from a simple one-dimensional stochastic model of population dynamics at the base of the crypt, we infer that this sensitivity is due to direct competition between wild-type and mutant cells at the base of the crypt. We also predict that increases in the extent of the spatial domain in which the mutant cells proliferate can give rise to counter-intuitive, non-linear changes to the probability of their fixation, due to effects that cannot be captured in simpler models
Thermo-acoustic wave propagation and reflection near the liquid-gas critical point
We study the thermo-acoustic wave propagation and reflection near the
liquid-gas critical point. Specifically, we perform a numerical investigation
of the acoustic responses in a near-critical fluid to thermal perturbations
based on the same setup of a recent ultrasensitive interferometry measurement
in CO2 [Y. Miura et al. Phys. Rev. E 74, 010101(R) (2006)]. The numerical
results agree well with the experimental data. New features regarding the
reflection pattern of thermo-acoustic waves near the critical point under pulse
perturbations are revealed by the proper inclusion of the critically diverging
bulk viscosity.Comment: 14 pages, 4 figures, Accepted by PRE (Rapid Communication
Implementing vertex dynamics models of cell populations in biology within a consistent computational framework
The dynamic behaviour of epithelial cell sheets plays a central role during development, growth, disease and wound healing. These processes occur as a result of cell adhesion, migration, division, differentiation and death, and involve multiple processes acting at the cellular and molecular level. Computational models offer a useful means by which to investigate and test hypotheses about these processes, and have played a key role in the study of cell–cell interactions. However, the necessarily complex nature of such models means that it is difficult to make accurate comparison between different models, since it is often impossible to distinguish between differences in behaviour that are due to the underlying model assumptions, and those due to differences in the in silico implementation of the model. In this work, an approach is described for the implementation of vertex dynamics models, a discrete approach that represents each cell by a polygon (or polyhedron) whose vertices may move in response to forces. The implementation is undertaken in a consistent manner within a single open source computational framework, Chaste, which comprises fully tested, industrial-grade software that has been developed using an agile approach. This framework allows one to easily change assumptions regarding force generation and cell rearrangement processes within these models. The versatility and generality of this framework is illustrated using a number of biological examples. In each case we provide full details of all technical aspects of our model implementations, and in some cases provide extensions to make the models more generally applicable
A theoretical investigation of the effect of proliferation and\ud adhesion on monoclonal conversion in the colonic crypt
Colorectal cancers are initiated by the accumulation of mutations in the colonic epithelium. Using a spatially structured cell-based model of a colonic crypt, we investigate the likelihood that the progeny of a mutated cell will dominate, or be sloughed out of, a crypt. Our approach is to perform multiple simulations, varying the spatial location of the initial mutation, and its proliferative and adhesive properties, to obtain statistical distributions for the probability of domination. Our simulations lead us to make a number of predictions. The process of monoclonal conversion always occurs, and does not require that the cell which initially gave rise to the population remains in the crypt. Mutations occurring more than one to two cells from the base of the crypt are unlikely to become the dominant clone. The probability of a mutant clone persisting in the crypt is sensitive to dysregulation of adhesion, and comparison with a one-dimensional model suggests that this is caused by competition directly at the base of the crypt.\ud
We also predict that increases in the extent of the spatial domain in which the mutant cells proliferate cause counter-intuitive non-linear changes to the probability of its fixation, due to effects that cannot be captured in simpler models
The limits of filopodium stability
Filopodia are long, finger-like membrane tubes supported by cytoskeletal
filaments. Their shape is determined by the stiffness of the actin filament
bundles found inside them and by the interplay between the surface tension and
bending rigidity of the membrane. Although one might expect the Euler buckling
instability to limit the length of filopodia, we show through simple energetic
considerations that this is in general not the case. By further analyzing the
statics of filaments inside membrane tubes, and through computer simulations
that capture membrane and filament fluctuations, we show under which conditions
filopodia of arbitrary lengths are stable. We discuss several in vitro
experiments where this kind of stability has already been observed.
Furthermore, we predict that the filaments in long, stable filopodia adopt a
helical shape
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