Faktor – Faktor yang Mempengaruhi Rentang Waktu Penyajian Laporan Keuangan ke Publik (Studi Empiris pada Perusahaan-Perusahaan Lq 45 yang Terdaftar di Bursa Efek Indonesia)

Company which is go public have to make annual report to BEI ( Indonesian stockexchange ) and stockholder annually according to the decision of BAPEPAM chairman No. Kep36/PM/2003, No 1 regulation X.K.2 about the obligation of giving periodical financial report, saythat periodic financial report with accountant reporting give to BAPEPAM at least on the lastthird month after the date of annual report. The result of company audit have to announce topublic through two Indonesian newspapaer periodically and on time.The purpose of this reseachis to test factors influencing time periode of financial report giving to public with criterium ofcompany, range of provitability, solvability, auditor reputation and kinds of auditor's opinion asindependent variableThe reseach population about company size, provitability, solvability, auditorreputation and opinion about the completion of annually financial audit report and publication ofannual financial report to public are LQ 45 company, registered at BEI 2004-2006. The datawhichis used is secundary data. Data analysis with normality, classical assumtion includingmoltikolinearitas test, heterokedastisitas test and autocorrelation, and also hipotesis test includingregression analysis and partial hipotesis ( uji t )First regression got the result that only ROA significanthy to time periode offinancial report giving to public annually ( Y1) with value of significant = 0,004<0,05. Secondregression got the result that only SIZE with value of significant 0,000<0,05, ROA value ofsignificant 0,026<0,05 dan OPINI with value of significant 0,000<0,05 that is significantlyinfluence to time periode of auditor's financial report announcement to public ( Y2

Subcellular distribution of carbonic anhydrase in Solanum tuberosum L. leaves

The intracellular compartmentation of carbonic anhydrase (CA; EC 4.2.1.1), an enzyme that catalyses the reversible hydration of CO2 to bicarbonate, has been investigated in potato (#Solanum tuberosum$ L.) leaves. Although enzyme activity was mainly located in chloroplasts (87% of total cellular activity), significant activity (13%) was also found in the cytosol. The corresponding CA isoforms were purified either from chloroplasts or crude leaf extracts, respectively. The cytosolic isoenzyme has a molecular mass of 255 000 and is composed of eight identical subunits with an estimated Mr of 30 000. The chloroplastic isoenzyme (Mr 220 000) is also an octamer composed of two different subunits with Mr estimated at 27 000 and 27 500, respectively. The N-terminal amino acid sequences of both chloroplastic CA subunits demonstrated that they were identical except that the Mr-27 000 subunit was three amino acids shorter than that of the Mr-27 500 subunit. Cytosolic and chloroplastic CA isoenzymes were found to be similarly inhibited by monovalent anions (Cl-, I-, N3- and NO3-) and by sulfonamides (ethoxyzolamide and acetozolamide). Both CA isoforms were found to be dependent on a reducing agent such as cysteine or dithiothreitol in order to retain the catalytic activity, but 2-mercaptoethanol was found to be a potent inhibitor. A polyclonal antibody directed against a synthetic peptide corresponding to the N-terminal amino acid sequence of the chloroplastic CA monomers also recognized the cytosolic CA isoform. This antibody was used for immunocytolocalization experiments which confirmed the intracellular compartmentation of CA : within chloroplasts, CA is restricted to the stroma and appears randomly distributed in the cytosol. (Résumé d'auteur

Pemetaan Risiko Bencana Tanah Longsor Kota Semarang

Semarang city is the capital province of Central Java, Indonesia, which is one of the major cities in Indonesia. Geological structure that is quite striking in the Semarang city is in the form of straightness and firm rock contact that is the reflection of the fault structure both horizontal and normal shear are fairly developed in the central and southern parts of the city. So it frequently occur natural disasters one of them is landslides. So they developed a mapping of landslides in order to reduce disaster losses through the map.In the making of landslide risk map, it is done in several stages, namely the threat map modeling, vulnerability modeling, capacity modeling, and risk modeling. Threat modeling result from the weighting using the overlay. Vulnerabilities and capacities modeling refer to the study of documents generated by the vulnerability assessment using weighting. While in risk map modeling, it is processed by using the Regulation Head of Disaster Management (Perka BNPB) No. 2 In 2012 formula and the VCA (Vulnerability Capacity Analysis) modifications to determine the risk classification of landslides.The results of the study is to determine the risk of landslides using the grading matrix formulation in accordance with the VCA modification produces a low risk area of 126,003 hectares in eight villages, the level of risk covered 323,141 hectares in ten villages and fifteen villages in 475,127 hectares of high risk level

Dielectric characterization of multiferroic magnetoelectric double-perovskite Y(Ni0.5Mn0.5)O3 thin films

We report on the functional properties of the Y(Ni0.5Mn0.5)O3 epitaxial thin films, growth by pulsed laser deposition, observing the clear features of their ferroelectric and ferromagnetic nature at cryogenic temperature. The characterization of temperature-dependent complex impedance spectroscopy has shown a dielectric anomaly around the ferromagnetic Curie temperature (100 K) indicative of coupling between magnetic and electric orders.The financial support by the Ministerio de Ciencia e Innovacion of the Spanish Government (Grant No. BES-2009-028641 and Project Nos. MAT2011-29269-C03-03, NANOSELECT, MAT2014-56063-C2-2-R, CSD2007-00041, MAT2015-73839-JIN, and IMAGINE CSD2009-00013) and Generalitat de Catalunya (2014 SGR 734) is acknowledged. E.C. would like to thank the National Science Centre of Poland under the PRELUDIUM (UMO-2015/17/N/ST5/ 01988) for financial support. I.F. acknowledges the financial support from the Spanish Ministry of Economy and Competitiveness, through the “Severo Ochoa” Programme for Centres of Excellence in R&D (SEV-2015-0496), and also the Juan de la Cierva–Incorporacion postdoctoral fellowship (IJCI- 2014-19102) from the Spanish Ministry of Economy and Competitiveness of Spanish Government.Peer reviewe

Efficacy, safety, and dose of Pafuramidine, a new oral drug for treatment of first stage sleeping sickness, in a phase 2a clinical study and phase 2b randomized clinical studies

Sleeping sickness (human African trypanosomiasis [HAT]) is caused by protozoan parasites and characterized by a chronic progressive course, which may last up to several years before death. We conducted two Phase 2 studies to determine the efficacy and safety of oral pafuramidine in African patients with first stage HAT.; The Phase 2a study was an open-label, non-controlled, proof-of-concept study where 32 patients were treated with 100 mg of pafuramidine orally twice a day (BID) for 5 days at two trypanosomiasis reference centers (Angola and the Democratic Republic of the Congo [DRC]) between August 2001 and November 2004. The Phase 2b study compared pafuramidine in 41 patients versus standard pentamidine therapy in 40 patients. The Phase 2b study was open-label, parallel-group, controlled, randomized, and conducted at two sites in the DRC between April 2003 and February 2007. The Phase 2b study was then amended to add an open-label sequence (Phase 2b-2), where 30 patients received pafuramidine for 10 days. The primary efficacy endpoint was parasitologic cure at 24 hours (Phase 2a) or 3 months (Phase 2b) after treatment completion. The primary safety outcome was the rate of occurrence of World Health Organization Toxicity Scale Grade 3 or higher adverse events. All subjects provided written informed consent.; Pafuramidine for the treatment of first stage HAT was comparable in efficacy to pentamidine after 10 days of dosing. The cure rates 3 months post-treatment were 79% in the 5-day pafuramidine, 100% in the 7-day pentamidine, and 93% in the 10-day pafuramidine groups. In Phase 2b, the percentage of patients with at least 1 treatment-emergent adverse event was notably higher after pentamidine treatment (93%) than pafuramidine treatment for 5 days (25%) and 10 days (57%). These results support continuation of the development program for pafuramidine into Phase 3

Investigation of magneto-structural phase transition in FeRh by reflectivity and transmittance measurements in visible and near-infrared spectral region

Magneto-structural phase transition in FeRh epitaxial layers was studied optically. It is shown that the transition between the low-temperature antiferromagnetic phase and the high-temperature ferromagnetic phase is accompanied by a rather large change of the optical response in the visible and near-infrared spectral ranges. This change is consistent with ab initio calculations of reflectivity and transmittance. Phase transition temperatures in a series of FeRh films with thicknesses ranging from 6 to 100 nm is measured thereby demonstrating the utility of the method to quickly characterise samples. Spatially resolved imaging of their magnetic properties with a micrometer resolution shows that the phase transition occurs at different temperatures in different parts of the sample

To respond or not to respond - a personal perspective of intestinal tolerance

For many years, the intestine was one of the poor relations of the immunology world, being a realm inhabited mostly by specialists and those interested in unusual phenomena. However, this has changed dramatically in recent years with the realization of how important the microbiota is in shaping immune function throughout the body, and almost every major immunology institution now includes the intestine as an area of interest. One of the most important aspects of the intestinal immune system is how it discriminates carefully between harmless and harmful antigens, in particular, its ability to generate active tolerance to materials such as commensal bacteria and food proteins. This phenomenon has been recognized for more than 100 years, and it is essential for preventing inflammatory disease in the intestine, but its basis remains enigmatic. Here, I discuss the progress that has been made in understanding oral tolerance during my 40 years in the field and highlight the topics that will be the focus of future research

Telling the collective story? Moroccan-Dutch young adults’ negotiation of a collective identity through storytelling

Researchers taking a social constructionist perspective on identity agree that identities are constructed and negotiated in interaction. However, empirical studies in this field are often based on interviewer–interviewee interaction or focus on interactions with members of a socially dominant out-group. How identities are negotiated in interaction with in-group members remains understudied. In this article we use a narrative approach to study identity negotiation among Moroccan-Dutch young adults, who constitute both an ethnic and a religious (Muslim) minority in the Netherlands. Our analysis focuses on the topics that appear in focus group participants’ stories and on participants’ responses to each other’s stories. We find that Moroccan-Dutch young adults collectively narrate their experiences in Dutch society in terms of discrimination and injustice. Firmly grounded in media discourse and popular wisdom, a collective narrative of a disadvantaged minority identity emerges. However, we also find that this identity is not uncontested. We use the concept of second stories to explain how participants negotiate their collective identity by alternating stories in which the collective experience of deprivation is reaffirmed with stories in which challenging or new evaluations of the collective experience are offered. In particular, participants narrate their personal experiences to challenge recurring evaluations of discrimination and injustice. A new collective narrative emerges from this work of joint storytelling

Durable graphite oxide nanocoating for high performing flame retarded foams

Recent developments in the design of water-based coatings encompassing platelet-like nanoparticles have clearly demonstrated the flame retardant potential of this approach for open cell flexible foams. However, the relatively high number of deposition steps required and the limited reports on the durability of the deposited coatings to multiple compression cycles currently represent the main constraints to this approach. This paper addresses these limitations by exploiting a few steps deposition procedure to produce coatings with durable flame retardant properties. Graphite oxide, sodium alginate and sodium hexametaphosphate were combined in a continuous protective coating that extends to the complex three-dimensional structure of the foam. The flame retardant properties of the coatings were evaluated before and after 1000 compression cycles. Even after such multiple deformations, the coated foams showed no melt dripping and self-extinguishment during flammability tests, as well as a highly reduced heat release rates (-70%) and total smoke release (-70%) during cone calorimetry tests. Furthermore, the ability to withstand the penetration of an impinging flame focused on one side of the coated foam for more than 5 min was also maintained. These results clearly demonstrate the durability of the coated foams, opening to real life application fields such as transports seats where high levels of flame retardancy must be maintained for long time under frequent mechanical stress

TOURISM DESTINATION PROMOTION THROUGH SOCIAL MEDIA : A CONTENT STUDY OF DMO GORONTALO

The promotion of tourism destinations via social media has significantly increased in the contemporary tourism industry. This paradigm shift is driven by advancements in information technology and the growing utilization of social media platforms. However, in Gorontalo region, particularly in Tomini Bay area, social media has not been fully leveraged by the Destination Marketing Organization (DMO) to market the region’s potential tourist attractions. Therefore, this study aims to evaluate the promotional content of tourism destinations in Tomini Bay area by the DMO on social media platforms, specifically Facebook and Instagram, as well as to understand tourists’ perceptions and responses to these promotional strategies. The research employs a mixed-method approach through content analysis and online surveys. The findings provide in-depth insights into the promotional strategies employed by DMO’s Gorontalo, tourists’ responses to these strategies, and recommendations for enhancing effective tourism promotion strategies. The study reveals that social media has not been utilized consistently and optimally by DMO Gorontalo which impacting the achievement of its tourism promotion objectives. To improve the effectiveness of tourism promotion strategies, several aspects need to be addressed, including: (1) consistency and frequency of promotional content uploads; (2) diversification of promotional content; and (3) optimization of user-generated content