LEVERAGING INTELLIGENCE AND BIG DATA IN THE MEXICAN NAVY’S PUBLIC SECURITY MISSION

When Mexican President López Obrador took office in 2018, he vowed to save the country from violence and corruption. His strategy involves creating a National Guard to fight violence and gradually withdrawing military forces from the cities. However, during its first five years, this force will be formed and trained by the military police of the Mexican Army and Navy. As other countries have leveraged technology and big data in their intelligence-led policing efforts, these tools have the potential to help the Mexican Navy in its mission to restore public security in the country and fight drug-trafficking networks. This thesis poses the question of how the Mexican Navy can implement intelligence-led security methodologies to increase the effectiveness of operations against organized crime and reduce levels of violence in the country. In applying the concepts of action research and contextual analysis of the essential issues manifest in Mexico’s security policy, this thesis examines the existing legal frameworks, policies, and decision-making processes to propose a new methodology to capitalize on the Navy’s strengths and opportunities while mitigating its threats and weaknesses. The thesis concludes with recommendations for Mexico to improve its intelligence-sharing platform using technological solutions and big data.Teniente de Fragata, Mexican NavyApproved for public release. Distribution is unlimited

Evaluation of Safety Enhancements in School Zones with Familiar and Unfamiliar Drivers

Traffic crashes in suburban school zones pose a serious safety concern due to a higher presence of school-age pedestrians and cyclists as well as potential speeding issues. A study that investigated speed selection and driver behavior in school zones was carried out using two populations from different topographical and cultural settings: Puerto Rico and Massachusetts. A school zone from Puerto Rico was recreated in driver simulation scenarios, and local drivers who were familiar with the environment were used as subjects. The Puerto Rico school simulation scenarios were replicated with subjects from Massachusetts to analyze the impact of drivers’ familiarity on the school-roadway environment. Twenty-four scenarios were built with pedestrians, on-street parked vehicles, and traffic flow used as simulation variables in the experiment. Results are presented in terms of speed behavior, reaction to the presence of pedestrians, speed compliance, mean reduction in speeds, and eye tracker analysis for both familiar and unfamiliar drivers

Ticagrelor in patients with diabetes and stable coronary artery disease with a history of previous percutaneous coronary intervention (THEMIS-PCI) : a phase 3, placebo-controlled, randomised trial

Background: Patients with stable coronary artery disease and diabetes with previous percutaneous coronary intervention (PCI), particularly those with previous stenting, are at high risk of ischaemic events. These patients are generally treated with aspirin. In this trial, we aimed to investigate if these patients would benefit from treatment with aspirin plus ticagrelor. Methods: The Effect of Ticagrelor on Health Outcomes in diabEtes Mellitus patients Intervention Study (THEMIS) was a phase 3 randomised, double-blinded, placebo-controlled trial, done in 1315 sites in 42 countries. Patients were eligible if 50 years or older, with type 2 diabetes, receiving anti-hyperglycaemic drugs for at least 6 months, with stable coronary artery disease, and one of three other mutually non-exclusive criteria: a history of previous PCI or of coronary artery bypass grafting, or documentation of angiographic stenosis of 50% or more in at least one coronary artery. Eligible patients were randomly assigned (1:1) to either ticagrelor or placebo, by use of an interactive voice-response or web-response system. The THEMIS-PCI trial comprised a prespecified subgroup of patients with previous PCI. The primary efficacy outcome was a composite of cardiovascular death, myocardial infarction, or stroke (measured in the intention-to-treat population). Findings: Between Feb 17, 2014, and May 24, 2016, 11 154 patients (58% of the overall THEMIS trial) with a history of previous PCI were enrolled in the THEMIS-PCI trial. Median follow-up was 3·3 years (IQR 2·8–3·8). In the previous PCI group, fewer patients receiving ticagrelor had a primary efficacy outcome event than in the placebo group (404 [7·3%] of 5558 vs 480 [8·6%] of 5596; HR 0·85 [95% CI 0·74–0·97], p=0·013). The same effect was not observed in patients without PCI (p=0·76, p interaction=0·16). The proportion of patients with cardiovascular death was similar in both treatment groups (174 [3·1%] with ticagrelor vs 183 (3·3%) with placebo; HR 0·96 [95% CI 0·78–1·18], p=0·68), as well as all-cause death (282 [5·1%] vs 323 [5·8%]; 0·88 [0·75–1·03], p=0·11). TIMI major bleeding occurred in 111 (2·0%) of 5536 patients receiving ticagrelor and 62 (1·1%) of 5564 patients receiving placebo (HR 2·03 [95% CI 1·48–2·76], p<0·0001), and fatal bleeding in 6 (0·1%) of 5536 patients with ticagrelor and 6 (0·1%) of 5564 with placebo (1·13 [0·36–3·50], p=0·83). Intracranial haemorrhage occurred in 33 (0·6%) and 31 (0·6%) patients (1·21 [0·74–1·97], p=0·45). Ticagrelor improved net clinical benefit: 519/5558 (9·3%) versus 617/5596 (11·0%), HR=0·85, 95% CI 0·75–0·95, p=0·005, in contrast to patients without PCI where it did not, p interaction=0·012. Benefit was present irrespective of time from most recent PCI. Interpretation: In patients with diabetes, stable coronary artery disease, and previous PCI, ticagrelor added to aspirin reduced cardiovascular death, myocardial infarction, and stroke, although with increased major bleeding. In that large, easily identified population, ticagrelor provided a favourable net clinical benefit (more than in patients without history of PCI). This effect shows that long-term therapy with ticagrelor in addition to aspirin should be considered in patients with diabetes and a history of PCI who have tolerated antiplatelet therapy, have high ischaemic risk, and low bleeding risk