Research of technology of personnel selection

In a market economy, one of the main success factors of the organization is personnel. This staff provides efficient use of all types of resources available to the organization from the staff depend on its economic performance and competitiveness. Management of the organization should always remember that it is responsible for the correct selection of people who could implement its strategy, as well as for ensuring that employees feel good at work, which would correspond to their abilities and opportunities.условиях рыночной экономики одним из главных факторов успеха организации является подбор персонала. Именно персонал обеспечивает эффективное использование любых видов ресурсов, имеющихся в распоряжении организации, от персонала зависят ее экономические показатели и конкурентоспособность. Руководству организации всегда нужно помнить о том, что оно отвечает за правильный подбор людей, которые могли бы реализовать ее стратегию, а так же за то, чтобы сотрудники хорошо чувствовали себя на работе, которая соответствовала бы их способностям и возможностям

The ephemeris, orbital decay, and masses of 10 eclipsing HMXBs

We take advantage of more than 10 years of monitoring of the eclipsing HMXB systems LMC X-4, Cen X-3, 4U 1700-377, 4U 1538-522, SMC X-1, IGR J18027-2016, Vela X-1, IGR J17252-3616, XTE J1855-026, and OAO 1657-415 with the ASM on-board RXTE and ISGRI on-board INTEGRAL to update their ephemeris. These results are used to refine previous measurements of the orbital period decay of all sources (where available) and provide the first accurate values of the apsidal advance in Vela X-1 and 4U 1538-522. Updated values for the masses of the neutron stars hosted in the ten HMXBs are also provided, as well as the long-term lightcurves folded on the sources best determined orbital parameters. These lightcurves reveal complex eclipse ingresses and egresses, that are understood mostly as being due to the presence of accretion wakes. The results reported in this paper constitute a database to be used for population and evolutionary studies of HMXBs, as well as theoretical modelling of long-term accretion in wind-fed X-ray binaries.Comment: Accepted for publication on A&

Creation and study of formulations as inhibitors of metal corrosion and scaling for stabilization water treatment in water utilization systems (a review)

This review summarizes studies for the past 5 years aimed at creation of efficient organophosphonate reagents for the stabilization water treatment aimed at preventing metal corrosion and scaling in water utilization systems.This study was carried out with state financial support provided by the Russian Ministry of Education and Science under Subsidy Grant Agreement No. 14.576.21.0017 of August 23, 2014

Improvement of the personnel adaptation system in the educational institution

In a personnel management system one of the important directions is the organization of system of adaptation of personnel in organization. The effective procedure of adaptation allows to avoid a set of problems in the internal environment of the organization, in particular in the field of social and psychological climate, labor productivity and a staff turnover.В системе управления персоналом одним из важных направлений является организация системы адаптации персонала в учреждении. Эффективная процедура адаптации позволяет избежать множество проблем во внутренней среде организации, в частности в области социально-психологического климата, производительности труда и текучести кадров

Photometric Properties of 47 Clusters of Galaxies: I. The Butcher-Oemler Effect

We present gri CCD photometry of 44 Abell clusters and 4 cluster candidates. Twenty one clusters in our sample have spectroscopic redshifts. Fitting a relation between mean g, r and i magnitudes, and redshift for this subsample, we have calculated photometric redshifts for the remainder with an estimated accuracy of 0.03. The resulting redshift range for the sample is 0.03<z<0.38. Color-magnitude diagrams are presented for the complete sample and used to study evolution of the galaxy population in the cluster environment. Our observations show a strong Butcher-Oemler effect (Butcher & Oemler 1978, 1984), with an increase in the fraction of blue galaxies (f_B) with redshift that seems more consistent with the steeper relation estimated by Rakos and Schombert (1995) than with the original one by Butcher & Oemler (1984). However, in the redshift range between ~ 0.08 and 0.2, where most of our clusters lie, there is a wide range of f_B values, consistent with no redshift evolution of the cluster galaxy population. A large range of f_B values is also seen between ~ 0.2 and 0.3, when Smail at al. (1998) x-ray clusters are added to our sample. The discrepancies between samples underscore the need for an unbiased sample to understand how much of the Butcher-Oemler effect is due to evolution, and how much to selection effects. We also tested the idea proposed by Garilli et al. (1996) that there is a population of unusually red galaxies which could be associated either with the field or clusters, but we find that these objects are all near the limiting magnitude of the images (20.5<r<22) and have colors that are consistent with those expected for stars or field galaxies at z ~ 0.7.Comment: 35 pages including 8 figures, submitted to A

The formation of energy supply culture of students within the framework of the educational project PJSC «Enel Russia» «Play energy»

В статье описан опыт формирования культуры энергосбережения студентов Асбестовского политехникума через участие в международном образовательном проекте «PlayEnergy» Публичного акционерного общества «ЭНЕЛ РОССИЯ». Проект способствует увеличению знаний о мире энергии, начиная с актуальных ключевых тем, таких, как инновации, эффективность, устойчивость, современные технологии, ответственное потребление.The article describes the experience of formation of energy supply culture of students GAPO WITH Asbestovsky Polytechnic School through the participation in the international educational project "PlayEnergy" of the Public joint-stock company "ENEL RUSSIA". The project contributes to the knowledge extension in the sphere of energy, beginning with such key themes, as innovation, efficiency, sustainability, modern technology, responsible consumption

PReS-FINAL-2041: Macrophage activation syndrome in the children with systemic juvenile idiopathic arthritis during the course of tocilizumab

Background Trauma exposure and posttraumatic stress disorder (PTSD) are common among individuals with a mental disorder, but symptoms often go undetected and untreated. Methods The aim of this study was to determine the prevalence of PTSD among a large sample of adults with psychiatric diagnoses and to establish factors associated with symptoms going undetected. Participants were 1,946 adults recruited by the National Centre for Mental Health. Structured interviews and validated self-report questionnaires were used to ascertain clinical and demographic information for analysis. Results The prevalence of participants screening positive for PTSD that had not been detected by clinical services was 13.9% [12.4–15.5%, 95% confidence interval]). Factors associated with undetected PTSD were female gender, younger age of first contact with psychiatric services, and lower household income. Especially, poor rates of detection were observed after traumatic events, such as child abuse and sexual assault. Conclusions Our findings demonstrate the need for routine assessment of trauma histories and symptoms of PTSD among individuals with anymental disorder

Treatment for Paget’s disease: surgical approaches

Breast cancer (BC) ranks first in the pattern of female malignancies (20.7 %) and remains the top cancer among women. Paget’s disease (PD) is a rare BC form that occurs in the orifice of the lactiferous tubes and that is characterized by involvement of the nipple, large ducts, often to form a lump in the breast; this rare abnormality is encountered in 0.5–5 % of all BC cases. PD has a number of peculiarities. According to different authors, PD is attended with invasive or noninvasive BC in most cases (90–98 %). The involvement is commonly multifocal. PD has a very high risk for a lump (100 and 96 % for palpable and nonpalpable breast tumors, respectively). Almost 50 % of these patients have palpable breast lumps. Despite the fact that the course of PD has its peculiarities because of the rarity of this abnormality, the approaches to its treatment are not different from those in other histopathological types of BC. As for the surgical treatment of PD, until the present time there have been many unsolved problems that remain a matter of debate. The surgical treatment of PD does not differ from the treatment of BC and is primarily determined by disease stage and tumor subtype. The volume of operations for PD varies: from Madden’s radical mastectomy to lumpectomy and sentinel lymph node biopsy. It should be kept in mind that besides nipple-areole complex involvement, invasive or noninvasive BC is often detected in PD. Organ-sparing surgery for PD is mainly a method of rehabilitation for patients. Whether organsparing surgery can be performed is also determined by breast size. Oncoplaplastic resections may be carried out for PD. If the patient wishes to preserve her breast, the range of both single-stage and delayed reconstructive operations is wide. The assessment of the biological features of a tumor and the more differentiated approach to therapy in this cohort of patents might improve considerable survival rates; the determination of indications for organ-sparing treatment is to improve quality of life in patients and their rehabilitation

Валідація методик кількісного визначення ризатриптану в дослідженнях біоеквівалентності генериків за процедурою біовейвер

Topicality. Proof of bioequivalence of generic and reference drugs according to biovaser procedure based on the BCS for simplified registration provides for determination of solubility of active substance for establishing the BCS class and kinetics of its release from test drugs in three buffer media. These studies should be carried out according to developed and validated assay methods of active substance.Aim. To establish validation performance of assay methods of Rizatriptan in a complex of studies on determination of bioequivalence of Rizatriptan drugs in form of tablets 5 mg and 10 mg according to biowaiver procedure.Materials and methods. Validation was carried out for assay methods of Rizatriptan simultaneously studying pH-dependent solubility and kinetics of release of active substance from generic and reference drugs in three buffer media. The study was performed in range of 25-125 % of nominal content of Rizatriptan in test solution in accordance with requirements of SPU in three buffer media according to main validation parameters: full predictable uncertainty of analysis results, specificity, accuracy, repeatability, linearity.Results and discussion. Correspondence of validation performance to the acceptance criteria in all dissolution media was established.Conclusions. Based on results of validation, it was justified and experimentally proved that assay methods of Rizatriptan are suitable for analytical support of in vitro bioequivalence studies of MP containing Rizatriptan.Актуальность. Доказательство биоэквивалентности генерического и референтного лекарственных средств по процедуре биовейвер на основании БСК для упрощенной регистрации предусматривает определение растворимости действующего вещества для установления класса БСК и кинетики его высвобождения из лекарственных средств в трех буферных средах. Эти исследования должны проводиться по разработанным и валидированным методикам количественного определения действующего вещества.Цель данной работы заключалась в установлении валидационных характеристик методик количественного определения ризатриптана в комплексе исследований по установлению биоэквивалентности лекарственных средств ризатриптана в форме таблеток по 5 мг и 10 мг по процедуре биовейвер.                                                                                    Материалы и методы. Валидация проведена одновременно для методик количественного определения ризатриптана при исследованиях рН-зависимой растворимости и кинетики высвобождения действующего вещества из генерических и референтных лекарственных средств в трех буферных средах. Исследование выполнено в диапазоне 25-125 % от номинального содержания ризатриптана в испытуемом растворе в соответствии с требованиями ГФУ в трех буферных средах по основным валидационным характеристикам: полная прогнозируемая неопределенность результатов анализов, специфичность, правильность, сходимость, линейность.                                                                                              Результаты и их обсуждение. Установлено соответствие валидационных характеристик критериям приемлемости во всех исследуемых средах растворения.                                                                                                Выводы. По результатам проведения валидации обосновано и экспериментально доказано, что методики количественного определения ризатриптана пригодны для аналитического сопровождения исследований биоэквивалентности in vitro ЛС с ризатриптаном.Актуальність. Доведення біоеквівалентності генеричного та референтного лікарських засобів за процедурою біовейвер на підставі БСК для спрощеної реєстрації передбачає визначення розчинності діючої речовини для встановлення класу БСК та кінетики її вивільнення з досліджуваних лікарських засобів у трьох буферних середовищах. Такі дослідження повинні проводитись за розробленими і валідованими методиками кількісного визначення діючої речовини.Мета даної роботи полягала у встановленні валідаційних характеристик методик кількісного визначення ризатриптану в комплексі досліджень зі встановлення біоеквівалентності лікарських засобів ризатриптану у формі таблеток по 5 мг та 10 мг за процедурою біовейвер.Матеріали та методи. Валідація проведена одночасно для методик кількісного визначення ризатриптану при дослідженнях рН-залежної розчинності та кінетики вивільнення діючої речовини з генеричних та референтних лікарських засобів у трьох буферних середовищах. Дослідження виконано у діапазоні 25-125 % від номінального вмісту ризатриптану у випробуваному розчині відповідно до вимог ДФУ у трьох буферних середовищах за основними валідаційними характеристиками: повна прогнозована невизначеність результатів аналізу, специфічність, правильність, збіжність, лінійність.Результати та їх обговорення. Встановлена відповідність валідаційних характеристик критеріям прийнятності у всіх досліджуваних середовищах розчинення.Висновки. За результатами проведення валідації обґрунтовано і експериментально доведено, що методики кількісного визначення ризатриптану придатні для аналітичного супроводу досліджень біоеквівалентності in vitro ЛЗ з ризатриптаном