TERAPIA INTRAVENOSA EM NEONATOLOGIA E NA PEDIATRIA: UMA REVISAO SISTEMÁTICA DA LITERATURA

Os avanços tecnológicos têm cada vez mais possibilitado, aos profissionais da área da saúde a realização de procedimentos técnicos, através de equipamentos e materiais sofisticados, que garantem um menor risco de falhas e conseqüentemente a mais rápida recuperação e maior satisfação do paciente e de sua família. Dentro deste contexto, inúmeras tecnologias podem ser mencionadas no cenário da atenção à saúde, com destaque especial para a terapia intravenosa, um procedimento secular, que é responsável por grande parte dos eventos adversos durante o período de internação hospitalar. Como prática hospitalar, a terapia intravenosa integra um dos procedimentos mais utilizados que envolvem direta ou indiretamente a atuação multidisciplinar. Todavia, a equipe de enfermagem possui uma interface de destaque no que se refere à execução da técnica de punção venosa periférica – inserção, manutenção e retirada, assegurando com segurança e eficácia o sucesso do tratamento do paciente (PEDREIRA & CHAUD, 2004). A utilização de terapia intravenosa através de cateteres periféricos requer habilidade e conhecimentos da Enfermeira, uma vez que o grande desafio está relacionado com a manutenção destes cateteres por maior tempo, porém diminuindo possíveis complicações relacionadas à terapia. Com o tratamento prolongado pode haver prejuízo da rede venosa. Por isso a importância do conhecimento técnico-científico do enfermeiro e da equipe sobre os mecanismos de instalação e manutenção da terapia intravenosa para a prevenção e detecção precoce de possíveis complicações e intercorrências. É competência e responsabilidade do enfermeiro a administração de medicação por via endovenosa, o que lhe confere autonomia profissional e exige conhecimento técnico-científico com relação aos cuidados com infusão venosa. 

Maxwell's Equations in the Myers-Perry Geometry

We demonstrate separability of the Maxwell's equations in the Myers-Perry-(A)dS geometry and derive explicit solutions for various polarizations. Application of our construction to the four-dimensional Kerr black hole leads to a new ansatz for the Maxwell field which has significant advantages over the previously known parameterization.Comment: 94 pages. V2: Appendix F added, typos fixe

ENVELHECIMENTO POPULACIONAL: ATUAÇÃO DA APS NA GARANTIA DO ACESSO À POPULAÇÃO IDOSA

OBJECTIVE: To elucidate the role of Primary Health Care to ensure access to health for the elderly population. METHOD: For the elaboration of the study, organizational methodological steps were stipulated for the construction and foundation of the present study, and these steps were successively: definition of the guiding question, sampling in the literature, data collection, critical analysis of the included studies, discussion of the results and presentation of the integrative review The filter used for the searches was with the descriptors; (Aging) AND (Primary Health Care) AND (Access to Health Services). RESULTS: The final sample consisted of 6 studies that resulted in a topic for discussion: Strategies to facilitate access to health care in the elderly population. CONCLUSION: It was possible to conclude that the Primary Care team needs to identify the main access difficulties of its elderly population, carrying out investigation, implementation and evaluation of the measures taken, in order to perceive whether they were effective within that population, seeking to facilitate access and ensuring principles such as equity, universality and comprehensiveness.OBJETIVO: Elucidar qual a atuação da Atenção Primária à Saúde para garantir o acesso à saúde para a população idosa. MÉTODO: Para a elaboração do estudo foram estipuladas etapas metodológicas organizacionais para a construção e fundamentação do presente estudo, sendo tais etapas sucessivamente: definição da pergunta norteadora, amostragem na literatura, coleta de dados, análise crítica dos estudos incluídos, discussão dos resultados e apresentação da revisão integrativa O filtro utilizado para as buscas foram com os descritores; (Envelhecimento) AND (Atenção Primária à Saúde) AND (Acesso aos serviços de Saúde). RESULTADOS: A amostra final foi constituída por 6 estudos que resultaram em um tópico  para discussão: Estratégias para facilitar o acesso à saúde da população idosa. CONCLUSÃO: Foi possível concluir que a equipe da Atenção Primária precisa identificar as principais dificuldades de acesso de sua população idosa, realizando investigação, implementação e avaliação das medidas realizadas, de forma a perceber se essas foram eficazes dentro daquela população, buscando a facilitação do acesso e garantindo princípios como equidade, universalidade e integralidade

O Papel fundamental da atenção primária na saúde sexual e planejamento familiar das mulheres

OBJECTIVE: To describe the fundamental role of primary care in women's sexual health and family planning. METHOD: It consists of an integrative review, carried out based on the following guiding question: What is the fundamental role of primary care in women's sexual health and family planning? using the PICO strategy, where “p” population: women receiving primary health care, “I” interest: Assessment of the influence of primary health care on women’s sexual health and family planning, and “C” and “O ” context: Impact of primary health care on women’s sexual health and family planning. The filter used for the searches was with the descriptors: “Primary health care”; "Family planning"; “Women’s health”, using the Boolean operator “AND” and “OR”. RESULTS: The final sample consisted of 6 articles, which resulted in 2 categories: Primary care for women's health in Brazil and its emergence; Importance of primary care in women's sexual health and family planning. CONCLUSION: It is understood that the support of the health professional is of great importance when providing care to women. Comprehensive support must be offered to women, welcoming them into Primary Care and resolving all their doubts.OBJETIVO: Descrever o papel o papel fundamental da atenção primária na saúde sexual e planejamento familiar das mulheres. MÉTODO: Consiste numa revisão integrativa, realizada com base na seguinte pergunta norteadora: Qual o papel fundamental da atenção primária na saúde sexual e planejamento familiar das mulheres? sendo utilizado a estratégia PICO, em que “p” população: mulheres atendidas na atenção primária a saúde, “I” interesse: Avaliação da influência da atenção primária à saúde na saúde sexual e planejamento familiar das mulheres, e “C” e “O” contexto: Impacto da atenção primária à saúde na saúde sexual e planejamento familiar das mulheres. O filtro utilizado para as buscas foi com os descritores: “Atenção Primária à saúde”; “Planejamento Familiar”; “Saúde da mulher”, utilizando o operador booleano “AND” e “OR”.  RESULTADOS: A amostra final foi constituída de 6 artigos, que resultaram em 2 categorias: Atenção primária a saúde da mulher no Brasil e seu surgimento; Importância da atenção primária na saúde sexual da mulher e planejamento familiar. CONCLUSÃO: Entende-se que, o apoio do profissional de saúde é de grande importância durante o atendimento a mulher, deve-se oferecer um suporte integral a mulher, acolhê-la na Atenção Básica sanando todas as suas dúvidas

High anti-SARS-CoV-2 antibody seroconversion rates before the second wave in Manaus, Brazil, and the protective effect of social behaviour measures: results from the prospective DETECTCoV-19 cohort

Background: The city of Manaus, Brazil, has seen two collapses of the health system due to the COVID-19 pandemic. We report anti-SARS-CoV-2 nucleocapsid IgG antibody seroconversion rates and associated risk factors in Manaus residents before the second wave of the epidemic in Brazil. Methods: A convenience sample of adult (aged ≥18 years) residents of Manaus was recruited through online and university website advertising into the DETECTCoV-19 study cohort. The current analysis of seroconversion included a subgroup of DETECTCoV-19 participants who had at least two serum sample collections separated by at least 4 weeks between Aug 19 and Oct 2, 2020 (visit 1), and Oct 19 and Nov 27, 2020 (visit 2). Those who reported (or had no data on) having a COVID-19 diagnosis before visit 1, and who were positive for anti-SARS-CoV-2 nucleocapsid IgG antibodies at visit 1 were excluded. Using an in-house ELISA, the reactivity index (RI; calculated as the optical density ratio of the sample to the negative control) for serum anti-SARS-CoV-2 nucleocapsid IgG antibodies was measured at both visits. We calculated the incidence of seroconversion (defined as RI values ≤1·5 at visit 1 and ≥1·5 at visit 2, and a ratio >2 between the visit 2 and visit 1 RI values) during the study period, as well as incidence rate ratios (IRRs) through cluster-corrected and adjusted Poisson regression models to analyse associations between seroconversion and variables related to sociodemographic characteristics, health access, comorbidities, COVID-19 exposure, protective behaviours, and symptoms. Findings: 2496 DETECTCoV-19 cohort participants returned for a follow-up visit between Oct 19 and Nov 27, 2020, of whom 204 reported having COVID-19 before the first visit and 24 had no data regarding previous disease status. 559 participants were seropositive for anti-SARS-CoV-2 nucleocapsid IgG antibodies at baseline. Of the remaining 1709 participants who were seronegative at baseline, 71 did not meet the criteria for seroconversion and were excluded from the analyses. Among the remaining 1638 participants who were seronegative at baseline, 214 showed seroconversion at visit 2. The seroconversion incidence was 13·06% (95% CI 11·52–14·79) overall and 6·78% (5·61–8·10) for symptomatic seroconversion, over a median follow-up period of 57 days (IQR 54–61). 48·1% of seroconversion events were estimated to be asymptomatic. The sample had higher proportions of affluent and higher-educated people than those reported for the Manaus city population. In the fully adjusted and corrected model, risk factors for seroconversion before visit 2 were having a COVID-19 case in the household (IRR 1·49 [95% CI 1·21–1·83]), not wearing a mask during contact with a person with COVID-19 (1·25 [1·09–1·45]), relaxation of physical distancing (1·31 [1·05–1·64]), and having flu-like symptoms (1·79 [1·23–2·59]) or a COVID-19 diagnosis (3·57 [2·27–5·63]) between the first and second visits, whereas working remotely was associated with lower incidence (0·74 [0·56–0·97]). Interpretation: An intense infection transmission period preceded the second wave of COVID-19 in Manaus. Several modifiable behaviours increased the risk of seroconversion, including non-compliance with non-pharmaceutical interventions measures such as not wearing a mask during contact, relaxation of protective measures, and non-remote working. Increased testing in high-transmission areas is needed to provide timely information about ongoing transmission and aid appropriate implementation of transmission mitigation measures. Funding: Ministry of Education, Brazil; Fundação de Amparo à Pesquisa do Estado do Amazonas; Pan American Health Organization (PAHO)/WHO.World Health OrganizationRevisión por pare

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Perspectivas epidemiológicas, clínicas e terapêuticas do transtorno bipolar em comorbidade com o uso de drogas: revisão de sistemática: Epidemiological, clinical and therapeutic perspectives of bipolar disorder in comorbidity with drug use: a systematic review

Conhecida como transtorno maníaco-depressivo, atualmente possui um novo nome: Transtorno Afetivo Bipolar, visto que com o passar do tempo foi se percebendo que esse transtorno não se tratava de uma alteração psicótica, e mais de um prejuízo afetivo. O transtorno bipolar possui alguns tipos, não se caracterizando em apenas uma forma, sua manifestação varia conforme o indivíduo e suas tendências, disforia e/ou euforia porém independente da forma expressa o paciente bipolar pode ter sua vida social comprometida, se não tratada, visto a irregularidade no estado de humor; bem como pode fazer uso de substâncias psicoativas, o que prejudica a sua condição clínica. Objetivo central da pesquisa é de apresentar a correlação do transtorno bipolar com o uso de drogas, mediante uma revisão de literatura integrativa realizada entre os meses de março de 2022 a julho de 2022, através da busca de artigos científicos nos bancos de dados online PubMed, Scielo e Google Acadêmico, utilizando como critério de refinamento de pesquisa artigos de todas as línguas publicados entre os anos 2000 e 2022

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost