1,520 research outputs found
Reconfiguring the borderlands of identity: Preparing social justice educators
This article offers multiple pedagogical approaches for mobilizing Gloria Anzaldúa\u27s metaphor of borderlands to prepare social justice educators to address issues of justice and equity in increasingly diverse classroom settings. It describes an experiential course in multicultural education, including innovative processes through which Education students analyze the borderlands of identity, society, and geography through critical self-analysis, fieldwork, and social action. By investigating the intersectionality of social justice issues and the social construction of identity, students attempt to transform the borders of their own identities and engage in action projects to begin a process of bridging the edges of cultural inequity
Designing Authentic Assignments to Engage Students
This session will offer strategies to participants which will empower them to design authentic research assignments that engage students and encourage the development of critical thinking and information literacy skills. The presenters will share and discuss their collaboration at Fairfield University, as a member of the biology faculty and an instructional librarian, to design an authentic assignment on the topic of the regulation of genetically modified organisms (GMOs) for an honors course that would incorporate information literacy skills. Participants will have the opportunity to analyze assignments and create their own authentic assignments using the concepts presented
MEL-28 Is Downstream of the Ran Cycle and Is Required for Nuclear-Envelope Function and Chromatin Maintenance
SummaryEarly embryonic development depends on the faithful execution of basic cell biological processes whose coordination remains largely unknown. With a global network analysis, we found MEL-28 to be associated with two types of complexes, one implicated in nuclear-envelope function and the other in chromatin organization [1]. Here, we show that MEL-28, a protein that shuttles between the nucleus and the kinetochore during the cell cycle, is required for the structural and functional integrity of the nuclear envelope. In addition, mel-28(RNAi) embryos exhibit defects in chromosome condensation, pronuclear migration, kinetochore assembly, and spindle assembly. This combination of mel-28(RNAi) phenotypes resemble those caused by depleting members of the Ran cycle in C. elegans[2], a conserved cellular signaling pathway that is required for mitotic spindle assembly, nuclear-envelope reformation after mitosis, and nucleocytoplasmic exchange (reviewed in [3–8]). Although MEL-28 localization to the nuclear periphery is not dependent on nuclear pore components, it is dependent on RAN-1 and other key components of the Ran cycle. Thus, MEL-28 is downstream of the Ran cycle and is required for both proper nuclear-envelope function and chromatin maintenance
Heathland creation on improved grassland using sulphur: is there a conflict between optimal application rates for plant and animal communities?
We examined the effectiveness of using elemental sulphur (a soil acidifier) as a method for creating heathland on improved pasture. We determined i) optimal rate of sulphur application to control mesotrophic grasses ii) if invertebrates avoid areas of sulphur application. Results indicated that optimal sulphur application attracted invertebrates
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Exploiting Citation Knowledge in Personalised Recommendation of Recent Scientific Publications
In this paper we address the problem of providing personalised recommendations of recent scientific publications to a particular user, and explore the use of citation knowledge to do so. For this purpose, we have generated a novel dataset that captures authors’ publication history and is enriched with different forms of paper citation knowledge, namely citation graphs, citation positions, citation contexts, and citation types. Through a number of empirical experiments on such dataset, we show that the exploitation of the extracted knowledge, particularly the type of citation, is a promising approach for recommending recently published papers that may not be cited yet. The dataset, which we make publicly available, also represents a valuable resource for further investigation on academic information retrieval and filtering
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Capturing and Exploiting Citation Knowledge for Recommending Recently Published Papers
With the continuous growth of scientific literature, discovering relevant academic papers for a researcher has become a challenging task, especially when looking for the latest, most recent papers. In this case, traditional collaborative filtering systems are ineffective, since they are unable to recommend items not previously seen, rated or cited. In this paper, we explore the potential of exploiting citation knowledge to provide a given user with relevant suggestions about recent scientific publications. A novel hybrid recommendation method that encapsulates such citation knowledge is proposed. Experimental results show improvements over baseline methods, evidencing benefits of using citation knowledge to recommend recently published papers in a personalised way. Moreover, as a result of our work, we also provide a unique dataset that, differently to previous corpora, contains detailed paper citation information
Un espace à construire pour le désir...
Question de femme ou question d'être? Y a-t-il un être au féminin ou une manière d'être femme? Des femmes interrogent la psychanalyse. Cet article propose un retour sur la notion de castration et sur les développements entourant la signification du phallus. L'expérience de la castration est présentée comme étant étroitement liée au processus de la sexuation et à la constitution même du sujet parlant. Cet article tente de faire état de la position féminine, qui questionne la castration. La psychanalyse n'apporte pas une réponse, elle pose une limite : celle de l'ordre symbolique dans lequel l'être parlant est inscrit. En deçà de cette limite de la castration, il reste à construire pour chaque femme et chaque homme, dans le Québec contemporain, un espace pour le désir.It is a matter of being woman or simply of being? Is there actually a feminine way to be? Here, women put psychanalysis into question. This article suggests a return to the notion of castration and to the developments surrounding the significance of the phallus. The castration experience is presented as being closely liked to the process of sexualization and to the individual's self-realization. The authors advance the woman's point of view, which questions castration. They find that psychoanalysis does not provide an answer, but imposes a limit: that of a symbolic order in which the individual must fit. Within the limiting phenomenon of castration, there remains the need for every man and woman in contemporary Québec society to share a sense of desire
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Oxylipins in triglyceride-rich lipoproteins of dyslipidemic subjects promote endothelial inflammation following a high fat meal.
Elevated triglyceride-rich lipoproteins (TGRL) in circulation is a risk factor for atherosclerosis. TGRL from subjects consuming a high saturated fat test meal elicited a variable inflammatory response in TNFα-stimulated endothelial cells (EC) that correlated strongly with the polyunsaturated fatty acid (PUFA) content. This study investigates how the relative abundance of oxygenated metabolites of PUFA, oxylipins, is altered in TGRL postprandially, and how these changes promote endothelial inflammation. Human aortic EC were stimulated with TNFα and treated with TGRL, isolated from subjects' plasma at fasting and 3.5 hrs postprandial to a test meal high in saturated fat. Endothelial VCAM-1 surface expression stimulated by TNFα provided a readout for atherogenic inflammation. Concentrations of esterified and non-esterified fatty acids and oxylipins in TGRL were quantified by mass spectrometry. Dyslipidemic subjects produced TGRL that increased endothelial VCAM-1 expression by ≥35%, and exhibited impaired fasting lipogenesis activity and a shift in soluble epoxide hydrolase and lipoxygenase activity. Pro-atherogenic TGRL were enriched in eicosapentaenoic acid metabolites and depleted in esterified C18-PUFA-derived diols. Abundance of these metabolites was strongly predictive of VCAM-1 expression. We conclude the altered metabolism in dyslipidemic subjects produces TGRL with a unique oxylipin signature that promotes a pro-atherogenic endothelial phenotype
Understanding and Preventing Falls: Perspectives of First Responders and Older Adults
OBJECTIVE. The objectives of this study were to identify characteristics of older adult fallers in a local community in Marin County, California, examine the perceptions of older adults who contacted a local fire district after a fall, examine the perceptions of first responders from a local fire district regarding falls and fall prevention, explore the degree of depression in older adult fallers, and identify strategies to prevent falls in older adults.
METHODS. This research study was an exploratory and retrospective descriptive study that utilized a mixed-method design. The researchers coded narratives from Patient Care Report (PCRs) provided by the fire district and also quantitatively analyzed PCRs to identify characteristics of older adult fallers. Researchers also qualitatively analyzed data gathered from focus groups with older adults and first responders and from phone interviews with community-dwelling older adults to understand their experiences regarding falls and fall prevention.
RESULTS. Findings revealed that the majority of fallers were female, at an average age of 81 years old, living at home and alone during the fall. Older adult participants associated falls with negative emotions and expressed a strong desire to maintain their independence despite experiencing falls and fall injuries. First responder participants experienced challenges when communicating with older adult fallers due to cognitive and psychosocial factors. The lack of coordination of services with care facility staff also posed a challenge for first responder participants.
CONCLUSION. As the older adult population increases, more older adults will fall and require emergency care from first responders. A collaboration between first responders and occupational therapists to develop and implement effective fall prevention programs for the community can potentially reduce falls and fall-related injuries and costs and improve the health and well-being of older adults
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