1,637 research outputs found
Injury to the Superior Gluteal Artery during Intramedullary Fixation of a Proximal Femoral Fracture - A Case Report
Proximal femoral fractures represent a health problem of global proportions. Iatrogenic vascular lesion in the treatment of these fractures is an unusual potentially lethal complication, reported in only 0.2% of trochanteric fractures treated with intramedullary implants. Superior gluteal artery injury is extremely rare, with only two cases reported in literature.info:eu-repo/semantics/publishedVersio
VVV-WIT-04: An extragalactic variable source caught by the VVV Survey
We report the discovery of VVV-WIT-04, a near-infrared variable source
towards the Galactic disk located ~0.2 arcsec apart from the position of the
radio source PMN J1515-5559. The object was found serendipitously in the
near-IR data of the ESO public survey VISTA Variables in the V\'ia L\'actea
(VVV). Our analysis is based on variability, multicolor, and proper motion data
from VVV and VVV eXtended surveys, complemented with archive data at longer
wavelengths. We suggest that VVV-WIT-04 has an extragalactic origin as the
near-IR counterpart of PMN J1515-5559. The Ks-band light-curve of VVV-WIT-04 is
highly variable and consistent with that of an Optically Violent Variable (OVV)
quasar. The variability in the near-IR can be interpreted as the redshifted
optical variability. Residuals to the proper motion varies with the magnitude
suggesting contamination by a blended source. Alternative scenarios, including
a transient event such as a nova or supernova, or even a binary microlensing
event are not in agreement with the available data.R.K.S. acknowledges support from CNPq/Brazil through
projects 308968/2016-6 and 421687/2016-9. P.W.L. is supported by STFC Consolidated Grant ST/R000905/1. Support for the authors is provided by the BASAL CONICYT Center for Astrophysics and Associated Technologies
(CATA) through grant AFB-170002, and the Ministry for
the Economy, Development, and Tourism, Programa Iniciativa Cient´ıfica Milenio through grant IC120009, awarded to
the Millennium Institute of Astrophysics (MAS). D.M. acknowledges support from FONDECYT through project Regular #1170121
Stem diameter and height of chrysanthemum cv Yoko ono as affected by gibberellic acid
The effect of gibberellic acid has been shown mainly to promote cell division and elongation. This study was aimed to evaluate the development of height and diameter of the stems of chrysanthemum cultivar Yoko ono by the applications of gibberellic acid (GA3) in the field. The treatments were composed of four doses (0, 40, 80 and 120 mg L-1) at 15 and 30 days after transplanting. From the findings, It can be concluded that GA3 significantly affected the diameter of stem at higher doses, and was unable to affect the height of stem.Key words: Dendranthema grandiflora, flowers, plant regulator, concentration
Decoding negative affect personality trait from patterns of brain activation to threat stimuli
INTRODUCTION: Pattern recognition analysis (PRA) applied to functional magnetic resonance imaging (fMRI) has been used to decode cognitive processes and identify possible biomarkers for mental illness. In the present study, we investigated whether the positive affect (PA) or negative affect (NA) personality traits could be decoded from patterns of brain activation in response to a human threat using a healthy sample. METHODS: fMRI data from 34 volunteers (15 women) were acquired during a simple motor task while the volunteers viewed a set of threat stimuli that were directed either toward them or away from them and matched neutral pictures. For each participant, contrast images from a General Linear Model (GLM) between the threat versus neutral stimuli defined the spatial patterns used as input to the regression model. We applied a multiple kernel learning (MKL) regression combining information from different brain regions hierarchically in a whole brain model to decode the NA and PA from patterns of brain activation in response to threat stimuli. RESULTS: The MKL model was able to decode NA but not PA from the contrast images between threat stimuli directed away versus neutral with a significance above chance. The correlation and the mean squared error (MSE) between predicted and actual NA were 0.52 (p-value=0.01) and 24.43 (p-value=0.01), respectively. The MKL pattern regression model identified a network with 37 regions that contributed to the predictions. Some of the regions were related to perception (e.g., occipital and temporal regions) while others were related to emotional evaluation (e.g., caudate and prefrontal regions). CONCLUSION: These results suggest that there was an interaction between the individuals' NA and the brain response to the threat stimuli directed away, which enabled the MKL model to decode NA from the brain patterns. To our knowledge, this is the first evidence that PRA can be used to decode a personality trait from patterns of brain activation during emotional contexts
Xanthogranuloma of the lacrimal sac as a manifestation of Wegener's granulomatosis
McGill Univ, Ctr Hlth, Dept Ophthalmol & Pathol, Montreal, PQ H3A 2B4, CanadaHenry C Witelson Ocular Pathol Lab, Montreal, PQ, CanadaUniversidade Federal de São Paulo, Dept Ophthalmol, UNIFESP, EPM, São Paulo, BrazilMcGill Univ, Ctr Hlth, Dept Ophthalmol, Montreal, PQ H3A 2B4, CanadaUniversidade Federal de São Paulo, Dept Ophthalmol, UNIFESP, EPM, São Paulo, BrazilWeb of Scienc
Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B
BACKGROUND: Entecavir is a potent and selective antiviral agent that has demonstrated efficacy in phase 2 studies in patients with hepatitis B e antigen (HBeAg)-negative chronic hepatitis B. METHODS: In this phase 3, double-blind trial, we randomly assigned 648 patients with HBeAg-negative chronic hepatitis B who had not previously been treated with a nucleoside analogue to receive 0.5 mg of entecavir or 100 mg of lamivudine once daily for a minimum of 52 weeks. The primary efficacy end point was histologic improvement (a decrease by at least two points in the Knodell necroinflammatory score, without worsening of fibrosis). RESULTS: Histologic improvement after 48 weeks of treatment occurred in 208 of 296 patients in the entecavir group who had adequate baseline liver-biopsy specimens that could be evaluated (70 percent), as compared with 174 of 287 such patients in the lamivudine group (61 percent, P=0.01). More patients in the entecavir group than in the lamivudine group had undetectable serum hepatitis B virus (HBV) DNA levels according to a polymerase-chain- reaction assay (90 percent vs. 72 percent, P<0.001) and normalization of alanine aminotransferase levels (78 percent vs. 71 percent, P = 0.045). The mean reduction in serum HBV DNA levels from baseline to week 48 was greater with entecavir than with lamivudine (5.0 vs. 4.5 log [on a base-10 scale] copies per milliliter, P<0.001). There was no evidence of resistance to entecavir. Safety and adverse-event profiles were similar in the two groups. CONCLUSIONS: Among patients with HBeAg-negative chronic hepatitis B who had not previously been treated with a nucleoside analogue, the rates of histologic improvement, virologic response, and normalization of alanine aminotransferase levels were significantly higher at 48 weeks with entecavir than with lamivudine. The safety profile of the two agents was similar, and there was no evidence of viral resistance to entecavir. Copyright © 2006 Massachusetts Medical Society.published_or_final_versio
Analysis of the Influence of Sparkout Time on Grinding Using Several Lubrication/Cooling Methods
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)The plunge cylindrical grinding operation has been widely employed in the manufacturing process of components which require excellent surface quality achieved within small ranges of dimensional tolerance. The sparkout time has proved to be an important parameter in this operation, contributing to obtain surfaces with high geometric and dimensional precision. This parameter, which is defined as the period in which there is no wheel radial feed, allows the elimination of elastic deformations that build up as the grinding wheel is fed. Experimentation with sparkout time was applied in the plunge cylindrical grinding operation and included the Minimum Quantity Lubrication (MQL) technique, which has proved to be an environmentally correct alternative, combining a small amount of lubricating oil with an intense flow rate of compressed air. The conventional lubrication and cooling method and the method involving the nozzle proposed by Webster [10] were also used. The results showed that longer sparkout times led to a decrease in tangential forces, wheel diametrical wear and surface roughness values for the MQL method.3114751Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)UNESP Sao Paulo State University at BauruFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP
Dermatological remedies in the traditional pharmacopoeia of Vulture-Alto Bradano, inland southern Italy
Dermatological remedies make up at least one-third of the traditional pharmacopoeia in southern Italy. The identification of folk remedies for the skin is important both for the preservation of traditional medical knowledge and in the search for novel antimicrobial agents in the treatment of skin and soft tissue infection (SSTI). Our goal is to document traditional remedies from botanical, animal, mineral and industrial sources for the topical treatment of skin ailments. In addition to SSTI remedies for humans, we also discuss certain ethnoveterinary applications.
Field research was conducted in ten communities in the Vulture-Alto Bradano area of the Basilicata province, southern Italy. We randomly sampled 112 interviewees, stratified by age and gender. After obtaining prior informed consent, we collected data through semi-structured interviews, participant-observation, and small focus groups techniques. Voucher specimens of all cited botanic species were deposited at FTG and HLUC herbaria located in the US and Italy.
We report the preparation and topical application of 116 remedies derived from 38 plant species. Remedies are used to treat laceration, burn wound, wart, inflammation, rash, dental abscess, furuncle, dermatitis, and other conditions. The pharmacopoeia also includes 49 animal remedies derived from sources such as pigs, slugs, and humans. Ethnoveterinary medicine, which incorporates both animal and plant derived remedies, is addressed. We also examine the recent decline in knowledge regarding the dermatological pharmacopoeia.
The traditional dermatological pharmacopoeia of Vulture-Alto Bradano is based on a dynamic folk medical construct of natural and spiritual illness and healing. Remedies are used to treat more than 45 skin and soft tissue conditions of both humans and animals. Of the total 165 remedies reported, 110 have never before been published in the mainland southern Italian ethnomedical literature
Evaluation of the color stability of two techniquesfor reproducing artificial irides after microwave polymerization
The use of ocular prostheses for ophthalmic patients aims to rebuild facial aesthetics and provide an artificial substitute to the visual organ. Natural intemperate conditions promote discoloration of artificial irides and many studies have attempted to produce irides with greater chromatic paint durability using different paint materials. OBJECTIVES: The present study evaluated the color stability of artificial irides obtained with two techniques (oil painting and digital image) and submitted to microwave polymerization. MATERIAL AND METHODS: Forty samples were fabricated simulating ocular prostheses. each sample was constituted by one disc of acrylic resin N1 and one disc of colorless acrylic resin with the iris interposed between the discs. The irides in brown and blue color were obtained by oil painting or digital image. The color stability was determined by a reflection spectrophotometer and measurements were taken before and after microwave polymerization. Statistical analysis of the techniques for reproducing artificial irides was performed by applying the normal data distribution test followed by 2-way ANOVA and Tukey HSD test (α=.05). RESULTS: Chromatic alterations occurred in all specimens and statistically significant differences were observed between the oil-painted samples and those obtained by digital imaging. There was no statistical difference between the brown and blue colors. Independently of technique, all samples suffered color alterations after microwave polymerization. CONCLUSION: The digital imaging technique for reproducing irides presented better color stability after microwave polymerization
Molecular characterisation of protist parasites in human-habituated mountain gorillas (Gorilla beringei beringei), humans and livestock, from Bwindi impenetrable National Park, Uganda
Over 60 % of human emerging infectious diseases are zoonotic, and there is growing evidence of the zooanthroponotic transmission of diseases from humans to livestock and wildlife species, with major implications for public health, economics, and conservation. Zooanthroponoses are of relevance to critically endangered species; amongst these is the mountain gorilla (Gorilla beringei beringei) of Uganda. Here, we assess the occurrence of Cryptosporidium, Cyclospora, Giardia, and Entamoeba infecting mountain gorillas in the Bwindi Impenetrable National Park (BINP), Uganda, using molecular methods. We also assess the occurrence of these parasites in humans and livestock species living in overlapping/adjacent geographical regions
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