1,538 research outputs found
The HISTRA digital platform: Research on HIStory of TRAnslation
[EN] HISTRA (HIStory of TRAnslation in Spanish) aims to transfer to an electronic resource a bulky archive of file cards manually compiled by Dr. Santoyo, an expert in the field of Translation History, who registered bibliographical references of Spanish translations of English works from the 16th century until the 1980s. This process has been carried out with the help of the tool entitled Koha-Kobli, an integrated system for library management, free and open source software carried out by the Grupo de Trabajo de las Bibliotecas de la Administración General del Estado. The work methodology guarantees an exhaustive bibliographic account of the references included and normalization of the registers, based on the Reglas de Catalogación, using the international format MARC21. HISTRA constitutes a robust platform for the retrieval of relevant information about translators and translated works, thus contributing to research in translation history, facilitating studies on literary reception of works translated from English into Spanish, authors and translators.S
A framework for effective management of condition based maintenance programs in the context of industrial development of E-Maintenance strategies
CBM (Condition Based Maintenance) solutions are increasingly present in industrial systems due to two
main circumstances: rapid evolution, without precedents, in the capture and analysis of data and
significant cost reduction of supporting technologies. CBM programs in industrial systems can become
extremely complex, especially when considering the effective introduction of new capabilities provided
by PHM (Prognostics and Health Management) and E-maintenance disciplines. In this scenario, any CBM
solution involves the management of numerous technical aspects, that the maintenance manager needs
to understand, in order to be implemented properly and effectively, according to the company’s strategy.
This paper provides a comprehensive representation of the key components of a generic CBM solution,
this is presented using a framework or supporting structure for an effective management of the CBM
programs. The concept “symptom of failure”, its corresponding analysis techniques (introduced by ISO
13379-1 and linked with RCM/FMEA analysis), and other international standard for CBM open-software
application development (for instance, ISO 13374 and OSA-CBM), are used in the paper for the
development of the framework. An original template has been developed, adopting the formal structure
of RCM analysis templates, to integrate the information of the PHM techniques used to capture the failure
mode behaviour and to manage maintenance. Finally, a case study describes the framework using the
referred template.Gobierno de Andalucía P11-TEP-7303 M
Effects of fire and three fire-fighting chemicals on main soil properties, plant nutrient content and vegetation growth and cover after 10 years.
The study addresses a knowledge-gap in the long-term ecological consequences of fire and fire-fighting
chemicals. Ten years after a prescribed fire and the application of three fire-fighting chemicals, their effects
on the soil-plant system were evaluated. Five treatments were established: unburnt soils (US) and burnt
soils treated with water alone (BS), foaming agent (BS+Fo), Firesorb (BS+Fi) and ammonium polyphosphate
(BS+Ap). Soils (0-2 cm depth) and foliar material of shrubs (Erica umbellata, Pterospartum tridentatum and
Ulex micranthus) and trees (Pinus pinaster) were analysed for total N, 15N, and soil-available and plant total
macronutrients and trace elements. Soil pH, NH4
+-N and NO3
--N; pine basal diameter and height; and shrub
cover and height were also measured. Compared with US plots, burnt soils had less nitrates and more Mo.
Although differences were not always significant, BS+Ap had the highest levels of soil available P, Na and
Al. Plants from BS+Ap plots had higher values of 15N (P. pinaster and E. umbellata), P (all species), Na (P.
tridentatum and U. micranthus) and Mg (E. umbellata and P. tridentatum) than other treatments; while K in
plants from BS+Ap plots was the highest among treatments for P. pinaster and the lowest for the shrubs.
Pines in US plots were higher and wider than in burnt treatments, except for BS+Ap, where the tallest and
widest trees were found, although half of them were either death (the second highest mortality after BS+Fi)
or had a distorted trunk. BS+Ap was the treatment with strongest effects on plants, showing E. umbellata
the lowest coverage and height, P. tridentatum the highest coverage, U. micranthus one of the lowest
coverages and being the only treatment where Genista triacanthos was absent. Consequently, it is concluded
that both fire and ammonium polyphosphate application had significant effects on the soil-plant system
after 10 years.Peer reviewe
El proceso constructivo del colegio de San Pablo en Granada. Análisis y divulgación mediante modelado 3D
[EN] The aim of this article is to facilitate the understanding of the historical phases of the complex construction process at the College of San Pablo, initiated in 1556 and in progress to this day, through three-dimensional virtual reconstructions, obtained from two-dimensional graphichypotheses as well as from the laser scanner survey of the part corresponding to the old Jesuit schools, in order to preserve its original architectural configuration almost intact.It is a building of great relevance for the city of Granada, being known as Jesuit College, University, and Law School, which throughout its history has undergone different transformations. The methodology used to obtain the main phases of the historical-construction process has been based on the collection and analysis of primary and secondary sources. The realization of virtual reconstructions, using 3D modelling and subsequent rendering has proven to be an efficient instrument of conceptual recreation of the spaces and shapes of the architectural complex, due to its great utility in future interventions in the building in addition to its ability to disseminate among the scientific community.[ES] El objetivo de este artículo es facilitar la comprensión de las fases históricas del complejo proceso constructivo del colegio de San Pablo, iniciado en 1556 hasta la actualidad, mediante reconstrucciones virtuales tridimensionales, obtenidas a partir de hipótesis gráficas bidimensionales y del levantamiento con escáner láser de la parte correspondiente a las antiguas escuelas jesuitas, por conservar casi intacta su configuración arquitectónica original.Se trata de un edificio de gran relevancia para la ciudad de Granada –colegio jesuita, universidad, facultad de Derecho–, que a lo largo de su historia ha sufrido diferentes transformaciones. La metodología utilizada para la obtención de las principales fases del proceso histórico-constructivo se ha basado en la recopilación y análisis de las fuentes primarias y secundarias, mientras que la realización de las reconstrucciones virtuales, mediante modelado 3D y su posterior renderización, ha resultado un eficaz instrumento de recreación conceptual de los espacios y formas del conjunto arquitectónico, por su gran utilidad en futuras intervenciones en el edificio y por su capacidad de divulgación a la comunidad científica. Departamento de Expresión Gráfica Arquitectónica y en la Ingeniería. Universidad de GranadaVílchez Lara, MDC.; Gómez-Blanco Pontes, AJ.; Fernández Casas, JM. (2021). Construction process of the College of San Pablo in Granada. Analysis and dissemination through 3D modelling. EGA Expresión Gráfica Arquitectónica. 26(42):102-113. https://doi.org/10.4995/ega.2021.12313OJS102113264
PBL in Programming Subjects at Engineering
This paper presents the PBL learning methodology
applied to the subject of Programming in Engineering. We show
two different perspectives, teacher and student. First, the point of
view of the teacher considers the design of the project, and
secondly student that considers its implementation
New Tools to Study DNA Double-Strand Break Repair Pathway Choice
A broken DNA molecule is difficult to repair, highly mutagenic, and extremely cytotoxic. Such breaks can be repaired by homology-independent or homology-directed mechanisms. Little is known about the network that controls the repair pathway choice except that a licensing step for homology-mediated repair exists, called DNA-end resection. The choice between these two repair pathways is a key event for genomic stability maintenance, and an imbalance of the ratio is directly linked with human diseases, including cancer. Here we present novel reporters to study the balance between both repair options in human cells. In these systems, a double-strand break can be alternatively repaired by homology-independent or -dependent mechanisms, leading to the accumulation of distinct fluorescent proteins. These reporters thus allow the balance between both repair pathways to be analyzed in different experimental setups. We validated the reporters by analyzing the effect of protein downregulation of the DNA end resection and non-homologous end-joining pathways. Finally, we analyzed the role of the DNA damage response on double-strand break (DSB) repair mechanism selection. Our reporters could be used in the future to understand the roles of specific factors, whole pathways, or drugs in DSB repair pathway choice, or for genome-wide screening. Moreover, our findings can be applied to increase gene-targeting efficiency, making it a beneficial tool for a broad audience in the biological sciences. © 2013 Gomez-Cabello et al.This work has been funded by a R+D+I grant from the Spanish Ministry of Economy and Competitivity (SAF2010-14877) and an European Research
Council (ERC) Starting Grant (DSBRECA).Peer Reviewe
New tools to study DNA double-strand break repair pathway choice
A broken DNA molecule is difficult to repair, highly mutagenic, and extremely cytotoxic. Such breaks can be repaired by homology-independent or homology-directed mechanisms. Little is known about the network that controls the repair pathway choice except that a licensing step for homology-mediated repair exists, called DNA-end resection. The choice between these two repair pathways is a key event for genomic stability maintenance, and an imbalance of the ratio is directly linked with human diseases, including cancer. Here we present novel reporters to study the balance between both repair options in human cells. In these systems, a double-strand break can be alternatively repaired by homology-independent or -dependent mechanisms, leading to the accumulation of distinct fluorescent proteins. These reporters thus allow the balance between both repair pathways to be analyzed in different experimental setups. We validated the reporters by analyzing the effect of protein downregulation of the DNA end resection and non-homologous end-joining pathways. Finally, we analyzed the role of the DNA damage response on double-strand break (DSB) repair mechanism selection. Our reporters could be used in the future to understand the roles of specific factors, whole pathways, or drugs in DSB repair pathway choice, or for genome-wide screening. Moreover, our findings can be applied to increase gene-targeting efficiency, making it a beneficial tool for a broad audience in the biological sciences
Análisis de la estructura porosa y ciclo de vida de morteros de reparación en base cemento con polímeros
Los
morteros
de
reparación
deben
ser
capaces
de
reproducir,
o
incluso
superar,
las
prestaciones
del
soporte
en
términos
de
resistencia
y
durabilidad.
Además,
los
morteros
de
reparación
deben
tener
una
adherencia
al
soporte
suficiente
para
garantizar
el
buen
comportamiento
de
la
estructura
reparada.
Se
presentan
los
resultados
de
una
campaña
experimental
llevada
a
cabo
con
dos
morteros
de
reparación
de
base
cemento,
uno
de
los
cuales
ha
sido
formulado
con
un
contenido
de
polímero
de
un
3,2%
de
la
masa
total.
Los
morteros
han
sido
evaluados
conforme
a
los
estándares
de
la
norma
europea
UNE-EN
1504
para
morteros
estructurales
R4;
además,
se
ha
estudiado
el
comportamiento
de
ambos
morteros
en
estado
fresco
y
su
estructura
porosa
y
microestructura
mediante
porosimetría
por
intrusión
de
mercurio;
adicionalmente,
se
han
realizado
ensayos
de
propiedades
durables.
Los
resultados
obtenidos
indican
un
refinamiento
de
poros
en
el
mortero
con
polímeros,
mejorando
sus
prestaciones.
Por
último,
se
incluye
un
análisis
comparativo
del
ciclo
de
vida
de
ambos
morteros
en
dos
ambientes
con
distinto
nivel
de
agresividad,
con
objeto
de
evaluar
la
sostenibilidad
y
la
repercusión
a
lo
largo
de
la
vida
útil
de
la
incorporación
de
polímero
a
los
morteros
de
reparación
Efecto de las condiciones de curado del hormigón en su comportamiento frente a ciclos hielo-deshielo
El objetivo de este trabajo es relacionar las condiciones de curado del hormigón y la adición de un inclusor de aire, con los daños producidos por los ciclos hielo-deshielo en hormigones curados con baja humedad y alta temperatura. Para ello se ha realizado una campaña experimental sobre probetas de hormigón curadas en condiciones extremas reales “in situ” de humedad y temperatura con y sin aire ocluido sometida a ciclo de hielo deshielo. El trabajo presenta la correlación de la evaluación del comportamiento mecánico del hormigón sometido a ciclos hielo-deshielo frente al grado de hidratación del hormigón y el volumen y tamaños de los poros. De los resultados obtenidos se concluye que las probetas sin aireante muestran un deterioro de sus propiedades mecánicas tras el ensayo de hielo-deshielo. Sin embargo, la inclusión de aire beneficia el comportamiento del hormigón frente a los ciclos hielo-deshielo, de modo que incluso mejoran sus propiedades mecánicas tras el ensayo. Este comportamiento anómalo se explica porque el proceso de hidratación del cemento continúa durante los ensayos hielo-deshielo, cerrando la red porosa. Este aspecto se ha podido confirmar con los ensayos de ATD y TG realizado
Risk assessment of an abandoned pyrite mine in Spain based on direct toxicity assays
This is the author’s version of a work that was accepted for publication in Science of the Total Environment. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in [SCIENCE OF THE TOTAL ENVIRONMENT 470-471 (2014)] http://dx.doi.org/10.1016/j.scitotenv.2013.09.101This research reports the risk assessment of an abandoned pyrite mine using direct toxicity assays of soil and groundwater samples taken at the site. The toxicity of As and heavy metals from mining soils to soil and aquatic organisms was studied using the Multispecies Soil System (MS-3) in soil columns. Ecotoxicological assessment was performed with soil samples diluted with a control soil at concentrations of 12.5, 25, 50 and 100% test soil/ soil (w/w). In this way, changes in the mobility and bioavailability of soil contaminants due to changes in geochemical soil properties via soil dilution were studied. The toxicity of water samples was tested on algae and Daphnia magna. The assessment of the mining area indicated that the current presence of As and heavy metals at the site may cause injuries to soil and aquatic organisms in the entire research area. Moreover, this investigation demonstrated that changes in geochemical conditions can increase the availability of arsenic and, consequently, the environmental risk of these soils. A good correlation was not found between toxicity parameters and the concentrations of soil contaminants based on total and extracted element concentrations. This finding reinforces the usefulness of direct toxicity assays for evaluating environmental riskThis work has been financed by the Community of Madrid through EIADES Project S-2009/AMB/1478 and by the Spanish Ministry of Education and Science, project CTM-2007-66401-CO2/ TECNO and CTM2010-21922-C02-0
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