112 research outputs found
Translational and rotational friction on a colloidal rod near a wall
We present particulate simulation results for translational and rotational
friction components of a shish-kebab model of a colloidal rod with aspect ratio
(length over diameter) in the presence of a planar hard wall.
Hydrodynamic interactions between rod and wall cause an overall enhancement of
the friction tensor components. We find that the friction enhancements to
reasonable approximation scale inversely linear with the closest distance
between the rod surface and the wall, for in the range between and
. The dependence of the wall-induced friction on the angle between
the long axis of the rod and the normal to the wall is studied and fitted with
simple polynomials in .Comment: 8 pages, 8 figure
Noise and Inertia-Induced Inhomogeneity in the Distribution of Small Particles in Fluid Flows
The dynamics of small spherical neutrally buoyant particulate impurities
immersed in a two-dimensional fluid flow are known to lead to particle
accumulation in the regions of the flow in which rotation dominates over shear,
provided that the Stokes number of the particles is sufficiently small. If the
flow is viewed as a Hamiltonian dynamical system, it can be seen that the
accumulations occur in the nonchaotic parts of the phase space: the
Kolmogorov--Arnold--Moser tori. This has suggested a generalization of these
dynamics to Hamiltonian maps, dubbed a bailout embedding. In this paper we use
a bailout embedding of the standard map to mimic the dynamics of impurities
subject not only to drag but also to fluctuating forces modelled as white
noise. We find that the generation of inhomogeneities associated with the
separation of particle from fluid trajectories is enhanced by the presence of
noise, so that they appear in much broader ranges of the Stokes number than
those allowing spontaneous separation
Oscillations and translation of a free cylinder in a confined flow
An oscillatory instability has been observed experimentally on an horizontal
cylinder free to move and rotate between two parallel vertical walls of
distance H; its characteristics differ both from vortex shedding driven
oscillations and from those of tethered cylinders in the same geometry. The
vertical motion of the cylinder, its rotation about its axis and its transverse
motion across the gap have been investigated as a function of its diameter D,
its density s, of the mean vertical velocity U of the fluid and of its
viscosity. For a blockage ratio D/H above 0.5 and a Reynolds number Re larger
then 14, oscillations of the rolling angle of the cylinder about its axis and
of its transverse coordinate in the gap are observed together with periodic
variations of the vertical velocity. Their frequency f is the same for the
sedimentation of the cylinder in a static fluid (U = 0) and for a non-zero mean
flow (U 6= 0). The Strouhal number St associated to the oscillation varies as
1/Re with : St.Re = 3 0.15. The corresponding period 1/f is then
independent of U and corresponds to a characteristic viscous diffusion time
over a distance ~ D, implying a strong influence of the viscosity. These
characteristics differ from those of vortex shedding and tethered cylinders for
which St is instead roughly constant with Re and higher than here
Hydrodynamic interactions of spherical particles in Poiseuille flow between two parallel walls
We study hydrodynamic interactions of spherical particles in incident
Poiseuille flow in a channel with infinite planar walls. The particles are
suspended in a Newtonian fluid, and creeping-flow conditions are assumed.
Numerical results, obtained using our highly accurate Cartesian-representation
algorithm [Physica A xxx, {\bf xx}, 2005], are presented for a single sphere,
two spheres, and arrays of many spheres. We consider the motion of freely
suspended particles as well as the forces and torques acting on particles
adsorbed at a wall. We find that the pair hydrodynamic interactions in this
wall-bounded system have a complex dependence on the lateral interparticle
distance due to the combined effects of the dissipation in the gap between the
particle surfaces and the backflow associated with the presence of the walls.
For immobile particle pairs we have examined the crossover between several
far-field asymptotic regimes corresponding to different relations between the
particle separation and the distances of the particles from the walls. We have
also shown that the cumulative effect of the far-field flow substantially
influences the force distribution in arrays of immobile spheres. Therefore, the
far-field contributions must be included in any reliable algorithm for
evaluating many-particle hydrodynamic interactions in the parallel-wall
geometry.Comment: submitted to Physics of Fluid
Acoustic radiation- and streaming-induced microparticle velocities determined by micro-PIV in an ultrasound symmetry plane
We present micro-PIV measurements of suspended microparticles of diameters
from 0.6 um to 10 um undergoing acoustophoresis in an ultrasound symmetry plane
in a microchannel. The motion of the smallest particles are dominated by the
Stokes drag from the induced acoustic streaming flow, while the motion of the
largest particles are dominated by the acoustic radiation force. For all
particle sizes we predict theoretically how much of the particle velocity is
due to radiation and streaming, respectively. These predictions include
corrections for particle-wall interactions and ultrasonic thermoviscous
effects, and they match our measurements within the experimental uncertainty.
Finally, we predict theoretically and confirm experimentally that the ratio
between the acoustic radiation- and streaming-induced particle velocities is
proportional to the square of the particle size, the actuation frequency and
the acoustic contrast factor, while it is inversely proportional to the
kinematic viscosity.Comment: 11 pages, 9 figures, RevTex 4-
Influence of confinement on the oscillations of a free cylinder in a viscous flow
We demonstrate and study experimentally two instabilities of a horizontal free cylinder in a vertical viscous Hele-Shaw flow; we show that they depend critically on the confinement of the flow with a different influence of transverse and lateral confinement characterized respectively by the ratios of the diameter (resp. the length) of the cylinder to the gap (resp. the width) of the cell. The onset of the instabilities depends largely on the transverse confinement: for a parameter between 0.4 and 0.6, one observes transverse horizontal oscillations of the cylinder perpendicular to the walls: their frequency is constant with the lateral and transverse confinements at a given cylinder velocity. This instability is shown to be locally two-dimensional and controlled by the local relative velocity between the cylinder and the fluids: it occurs down to Reynolds numbers based on the cell gap ≃ 15, far below the corresponding 2D vortex shedding thresholds (150−250) for fixed cylinders between parallel planes. Above transverse confinements of the order of 0.55, we observe a fluttering motion with periodic oscillations of the tilt angle of the cylinder from the horizontal and of its horizontal position: their frequency decreases strongly as the lateral confinement increases but is independent of the transverse confinement and the cylinder velocity.Fil: Gianorio, Luciano. Universidad de Buenos Aires. Facultad de Ingeniería. Departamento de Física. Grupo de Medios Porosos; ArgentinaFil: D'angelo, María Verónica. Universidad de Buenos Aires. Facultad de Ingeniería. Departamento de Física. Grupo de Medios Porosos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Cachile, Mario Andres. Universidad de Buenos Aires. Facultad de Ingeniería. Departamento de Física. Grupo de Medios Porosos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Hulin, Jean Pierre. Universite Paris Sud; FranciaFil: Auradou, Harold. Universite Paris Sud; Franci
Inverse lift: a signature of the elasticity of complex fluids?
To understand the mechanics of a complex fluid such as a foam we propose a
model experiment (a bidimensional flow around an obstacle) for which an
external sollicitation is applied, and a local response is measured,
simultaneously. We observe that an asymmetric obstacle (cambered airfoil
profile) experiences a downards lift, opposite to the lift usually known (in a
different context) in aerodynamics. Correlations of velocity, deformations and
pressure fields yield a clear explanation of this inverse lift, involving the
elasticity of the foam. We argue that such an inverse lift is likely common to
complex fluids with elasticity.Comment: 4 pages, 4 figures, revised version, submitted to PR
Two-dimensional flow of foam around an obstacle: force measurements
A Stokes experiment for foams is proposed. It consists in a two-dimensional
flow of a foam, confined between a water subphase and a top plate, around a
fixed circular obstacle. We present systematic measurements of the drag exerted
by the flowing foam on the obstacle, \emph{versus} various separately
controlled parameters: flow rate, bubble volume, bulk viscosity, obstacle size,
shape and boundary conditions. We separate the drag into two contributions, an
elastic one (yield drag) at vanishing flow rate, and a fluid one (viscous
coefficient) increasing with flow rate. We quantify the influence of each
control parameter on the drag. The results exhibit in particular a power-law
dependence of the drag as a function of the bulk viscosity and the flow rate
with two different exponents. Moreover, we show that the drag decreases with
bubble size, and increases proportionally to the obstacle size. We quantify the
effect of shape through a dimensioned drag coefficient, and we show that the
effect of boundary conditions is small.Comment: 26 pages, 13 figures, resubmitted version to Phys. Rev.
Dynamics of a small neutrally buoyant sphere in a fluid and targeting in Hamiltonian systems
We show that, even in the most favorable case, the motion of a small
spherical tracer suspended in a fluid of the same density may differ from the
corresponding motion of an ideal passive particle. We demonstrate furthermore
how its dynamics may be applied to target trajectories in Hamiltonian systems.Comment: See home page http://lec.ugr.es/~julya
Effects of Peroral Omega-3 Fatty Acid Supplementation on Cerebrospinal Fluid Biomarkers in Patients with Alzheimer’s Disease: A Randomized Controlled Trial—The OmegAD Study
Background:
Studies have suggested a connection between a decrease in the levels of polyunsaturated fatty acids (PUFAs) and Alzheimer’s disease (AD). We aimed to assess the effect of supplementation with omega-3 fatty acids (n-3 FAs) on biomarkers analyzed in the cerebrospinal fluid (CSF) of patients diagnosed with AD. /
Objective:
To investigate the effects of daily supplementation with 2.3 g of PUFAs in AD patients on the biomarkers in CSF described below. We also explored the possible correlation between these biomarkers and the performance in the cognitive test Mini-Mental State Examination (MMSE). /
Methods:
Thirty-three patients diagnosed with AD were randomized to either treatment with a daily intake of 2.3 g of n-3 FAs (n = 18) or placebo (n = 15). CSF samples were collected at baseline and after six months of treatment, and the following biomarkers were analyzed: Aβ 38, Aβ 40, Aβ 42, t-tau, p-tau, neurofilament light (NfL), chitinase-3-like protein 1 (YKL-40), acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), soluble IL-1 receptor type II (sIL-1RII), and IL-6. /
Results:
There were no significant differences between the groups concerning the level of the different biomarkers in the CSF at baseline. Within the treatment group, there was a small but significant increase in both YKL-40 (p = 0.04) and NfL (p = 0.03), while the other CSF biomarkers remained stable. /
Conclusion:
Supplementation with n-3 FAs had a statistically significant effect on NfL and YKL-40, resulting in an increase of both biomarkers, indicating a possible increase of inflammatory response and axonal damage. This increase in biomarkers did not correlate with MMSE score. /
Trial registration: clinicaltrial.gov Identifier: NCT00211159
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