Aggressive Central Giant Cell Granuloma: A Case Report

Central giant cell granuloma (CGCG) is a benign non odontogenic lesion of jaw that may show aggressive behavior. It is classified as aggressive and non-aggressive lesion on the basis of biological behavior and radiographic features. Central giant cell lesion is more frequent in children and young adult before the age of 30 years with female predilection, with characteristic radiological and histopathological features. Here we present a case of a 35 years old female with clinical and radiological diagnosis of central giant cell lesion in posterior mandible confirmed by histopathology. A surgical approach with regular follow up is the treatment of choice in most of the cases. Key Words: Calcitonin, Corticosteroid, Curettage, Enucleation, Giant cell lesio

Brown tumor of hyperparathyroidism Of anterior maxilla: case report: Case report

Hyperparathyroidism is characterized by the overproduction of parathyroid hormone (PTH). Hyperparathyroidism can be Primary, secondary and tertiary, In all these forms of hyperparathyroidism there is osteoclast mediated bone resorption which is caused by excess Parathyroid hormone levels that produce bone lesion called brown tumor of hyperparathyroidism. Brown tumor of Hyperparathyroidism is a benign non-odontogenic giant cell lesion of jaw with multinucleated giant cells. The term brown tumor is derived from the brown color of lesion as seen on surgical exploration. The characteristic discoloration is result of hemosiderin production. The brown tumor regress usually after hyperparathyroidism has been successfully corrected. Its surgical excision is usually not recommended until lesion is large symptomatic, at a risk of pathological fracture and recurrence. All the giant cell lesion are identical histologically and must be distinguished based on clinical, radiographic and biochemical means .Here we present a case of Brown tumor that reoccurred in 13 years old girl in anterior maxilla