Risk stratifiers for arrhythmic and non-arrhythmic mortality after acute myocardial infarction

Open Access. Publicado online: 2-Jul-2018The effective discrimination between patients at risk of Arrhythmic Mortality (AM) and Non-Arrhythmic Mortality (NAM) constitutes one of the important unmet clinical needs. Successful risk assessment based on Electrocardiography (ECG) records is greatly improved by the combination of different indices reflecting not only the pathological substrate but also the autonomic regulation of cardiac electrophysiology. This study assesses the cardiac risk stratification capacity of two new Heart Rate Variability (HRV) parameters, Breath Concurrence 6 (BC6) -sinusoidal RR variability of 6 heart beats per breath cycle- and Primary Ectopia (PE) -presence of early ventricular contractions of any etiology- together with the Deceleration Capacity (DC). While BC6 characterizes the response to physiological and pathophysiological stimuli, PE qualifies autonomic cardiac electrophysiology. The analysis of the European Myocardial Infarct Amiodarone Trial (EMIAT) database indicates that BC6 is related with the risk of Arrhythmic Mortality (AM) and PE with the risk of Non-Arrhythmic Mortality. BC6 is the only single parameter that significantly discriminates between AM and NAM. While the combination of BC6 and DC contributes to the identification of AM risk, PE together with DC improves the prediction of NAM in patients with severe ischemic heart disease

Limpeza clonal.

bitstream/item/140367/1/limpeza-clonal.pd

Limpeza clonal: cuidados com as mudas para obter um vinhedo sadio.

bitstream/item/140369/1/limpeza-clonal-pac.pd

Produção sadia desde a origem.

Made available in DSpace on 2012-07-03T01:00:43Z (GMT). No. of bitstreams: 1 NICKELCultivarHFv5n26p262004.pdf: 639646 bytes, checksum: 0cbf2ec614dceefa92bd17789297d3f0 (MD5) Previous issue date: 2005-02-1

Obtenção de material propagativo livre de vírus e diagnóstico de vírus em macieiras e pereiras.

Principais vírus da macieira e da pereira. Danos causados por vírus. Limpeza clonal: produção de macieiras e pereiras livres de vírus. Análises e testes de avaliação de sanidade.bitstream/item/60758/1/CNPUV-DOC.-69-09.pd

Detection of Viruses in Apples and Pears by Real Time RT-PCR Using 5'-Hydrolysis Probes

Apple stem pitting virus (ASPV), Apple stem grooving virus (ASGV), Apple chlorotic leaf spot virus (ACLSV) and Apple mosaic virus (ApMV) are common in apples and pears and the main targets of virus elimination from propagation material. The objective of this work was to design primers and probes for a real time RT-PCR protocol for detection of the four above viruses. FAM/TAMRA-labeled probes and primers were designed by searching for highly conserved nucleotide regions in the coat protein gene of the four viruses. Infection levels in analyzed apple samples were 92.6, 96.4, 100 and 88% for ASGV, ASPV, ACLSV and ApMV, respectively. In pears, all pre-existing ASPV infections were detected. Viral infections were confirmed in a selection of commercial cultivars of apples and pear scions, and quince rootstocks, demonstrating the sensitivity and reliability of the designed primers and probes. Real time RT-PCR using 5'-labeled probes is suitable for checking sanitary quality as a routine test in certification programs

Metabolitos secundarios de Berberís empetrifolia

Berberís empetrifolia Lam. ha sido parcialmente estudiada en cuanto a su contenido de alcaloides cuaternarios. Al reestudiar la corteza y madera de tallos subterráneos de esta planta fue posible aislar un alcaloide dimérico, la paquistanina, y el lignano siringarresinol. Este lignano parece ser un componente común a varias especies chilenas de Berberís; la paquistanina, por el contrario, es una base del tipo aporfinabencilisoquinolina que hasta ahora sólo habia sido encontrada en especies asiáticas del género