ОБОСНОВАНИЕ МОДЕЛИ РЫНКА В СОВРЕМЕННОМ РОССИЙСКОМ ЭКОНОМИЧЕСКОМ ДИСКУРСЕ: ДИАЛОГ-МОНОЛОГ

Modern science has at its disposal a number of philosophical and psychological theories devoted to the analysis of organization and self-organization, personal self-identification, inculturation, socialization, self-interpretation, and the identification of dominant features of the mentality of peoples. However, in cultural processes, the formation and development of the essence of the Russian mentality in sociocultural and natural dimensions are becoming most important today. Economics and linguistics are two areas of science that a person unites - acting and thinking (speaking). According to the definition of the famous English economist A. Marshall, the economy is "the doctrine of the normal functioning of humanity." The economy is fundamentally different from the exact and natural sciences in that it deals not with an individual, but with a member of society, subject to the influence of tradition, national mentality, and political institutions. The theoretical significance of the work is connected with the further development of the problem of the integration of sciences. The findings contribute to the expansion of existing ideas about the role of the economy in life and the language picture of the human world.La ciencia moderna tiene a su disposición una serie de teorías filosóficas y psicológicas dedicadas al análisis de la organización y la autoorganización, la autoidentificación personal, la inculturación, la socialización, la autointerpretación y la identificación de las características dominantes de la mentalidad de los pueblos. Sin embargo, en los procesos culturales, la formación y el desarrollo de la esencia de la mentalidad rusa en las dimensiones socioculturales y naturales son cada vez más importantes hoy en día. La economía y la lingüística son dos áreas de la ciencia que una persona une: actuar y pensar (hablar). Según la definición del famoso economista inglés A. Marshall, la economía es "la doctrina del funcionamiento normal de la humanidad". La economía es fundamentalmente diferente de las ciencias exactas y naturales en que trata no con un individuo, sino con un miembro de la sociedad, sujeto a la influencia de la tradición, la mentalidad nacional y las instituciones políticas. La importancia teórica del trabajo está relacionada con el desarrollo posterior del problema de la integración de las ciencias. Los hallazgos contribuyen a la expansión de las ideas existentes sobre el papel de la economía en la vida y la imagen lingüística del mundo humano.Современная наука располагает рядом философских и психологических теорий, посвященных анализу организации и самоорганизации, личностной самоидентификации, инкультурации, социализации, самоинтерпретации, выявлению доминирующих черт менталитета народов. Однако в культурных процессах становление и развитие сущности российского менталитета в социокультурном и природном измерениях приобретает сегодня важнейшее значение.Экономика и лингвистика-это две области науки, которые объединяет человек-действие и мышление (речь). Согласно определению известного английского экономиста А. Маршалла, экономика-это "учение о нормальной жизнедеятельности человечества". Экономика принципиально отличается от точных и естественных наук тем, что она имеет дело не с индивидом, а с членом общества, подверженным влиянию традиций, национального менталитета и политических институтов.Теоретическая значимость работы связана с дальнейшей разработкой проблемы интеграции наук. Полученные результаты способствуют расширению существующих представлений о роли экономики в жизни и языковой картины мира человека

Global nomads, cultural chameleons, strange ones or immigrants? An exploration of Third Culture Kid terminology with reference to the United Arab Emirates

© The Author(s) 2019. The term ‘Third Culture Kid’ (TCK) is commonly used to denote children living in a host culture other than their passport culture during their developmental years. However, its meaning in relation to other terminology referring to a similar concept is a source of interest for many stakeholders. This paper opens up opportunities for further exploring and critiquing the definition of TCK, and opening this up to case studies within the context of the United Arab Emirates and more widely. It is critical to clarify the terminology in light of unprecedented levels of international migration throughout the world. This paper reviews the meaning of culture in relation to TCKs, and explores the meaning of the TCK concept as well as a number of other terms used as alternatives to TCK. A contextualization of the literature follows in relation to the researchers’ own lived experiences in the United Arab Emirates. The term TCK can be seen as part of the general stock of theoretical concepts. This paper acknowledges that it cannot catch all nuances of migrant children in the global context

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. RESULTS: At 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in the 300-mg group than in the placebo group. Canakinumab did not reduce lipid levels from baseline. At a median follow-up of 3.7 years, the incidence rate for the primary end point was 4.50 events per 100 person-years in the placebo group, 4.11 events per 100 person-years in the 50-mg group, 3.86 events per 100 person-years in the 150-mg group, and 3.90 events per 100 person-years in the 300-mg group. The hazard ratios as compared with placebo were as follows: in the 50-mg group, 0.93 (95% confidence interval [CI], 0.80 to 1.07; P = 0.30); in the 150-mg group, 0.85 (95% CI, 0.74 to 0.98; P = 0.021); and in the 300-mg group, 0.86 (95% CI, 0.75 to 0.99; P = 0.031). The 150-mg dose, but not the other doses, met the prespecified multiplicity-adjusted threshold for statistical significance for the primary end point and the secondary end point that additionally included hospitalization for unstable angina that led to urgent revascularization (hazard ratio vs. placebo, 0.83; 95% CI, 0.73 to 0.95; P = 0.005). Canakinumab was associated with a higher incidence of fatal infection than was placebo. There was no significant difference in all-cause mortality (hazard ratio for all canakinumab doses vs. placebo, 0.94; 95% CI, 0.83 to 1.06; P = 0.31). Conclusions: Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering. (Funded by Novartis; CANTOS ClinicalTrials.gov number, NCT01327846.