Frequency-domain gravitational waves from non-precessing black-hole binaries. I. New numerical waveforms and anatomy of the signal

In this paper we discuss the anatomy of frequency-domain gravitational-wave signals from non-precessing black-hole coalescences with the goal of constructing accurate phenomenological waveform models. We first present new numerical-relativity simulations for mass ratios up to 18 including spins. From a comparison of different post-Newtonian approximants with numerical-relativity data we select the uncalibrated SEOBNRv2 model as the most appropriate for the purpose of constructing hybrid post-Newtonian/numerical-relativity waveforms, and we discuss how we prepare time-domain and frequency-domain hybrid data sets. We then use our data together with results in the literature to calibrate simple explicit expressions for the final spin and radiated energy. Equipped with our prediction for the final state we then develop a simple and accurate merger-ringdown-model based on modified Lorentzians in the gravitational wave amplitude and phase, and we discuss a simple method to represent the low frequency signal augmenting the TaylorF2 post-Newtonian approximant with terms corresponding to higher orders in the post-Newtonian expansion. We finally discuss different options for modelling the small intermediate frequency regime between inspiral and merger-ringdown. A complete phenomenological model based on the present work is presented in a companion paper.Comment: 17 pages, 18 figures ,minor edits to tex

Frequency-domain gravitational waves from non-precessing black-hole binaries. II. A phenomenological model for the advanced detector era

We present a new frequency-domain phenomenological model of the gravitational-wave signal from the inspiral, merger and ringdown of non-precessing (aligned-spin) black-hole binaries. The model is calibrated to 19 hybrid effective-one-body--numerical-relativity waveforms up to mass ratios of 1:18 and black-hole spins of $|a/m| \sim 0.85$ ($0.98$ for equal-mass systems). The inspiral part of the model consists of an extension of frequency-domain post-Newtonian expressions, using higher-order terms fit to the hybrids. The merger-ringdown is based on a phenomenological ansatz that has been significantly improved over previous models. The model exhibits mismatches of typically less than 1\% against all 19 calibration hybrids, and an additional 29 verification hybrids, which provide strong evidence that, over the calibration region, the model is sufficiently accurate for all relevant gravitational-wave astronomy applications with the Advanced LIGO and Virgo detectors. Beyond the calibration region the model produces physically reasonable results, although we recommend caution in assuming that \emph{any} merger-ringdown waveform model is accurate outside its calibration region. As an example, we note that an alternative non-precessing model, SEOBNRv2 (calibrated up to spins of only 0.5 for unequal-mass systems), exhibits mismatch errors of up to 10\% for high spins outside its calibration region. We conclude that waveform models would benefit most from a larger number of numerical-relativity simulations of high-aligned-spin unequal-mass binaries.Comment: 27 pages, 21 figures, Updated coefficients tabl

Diseño y personalización de contextos educativos inclusivos. Estrategias y tecnologías didácticas

Un futuro sostenible y justo para la infancia y la juventud pasa por el compromiso con una educación que acoge y respeta a todos y a todas en sus trayectorias escolares. La educación inclusiva, entendida como derecho, es reconocer la diversidad de identidades que nos conduce a la eliminación de cualquier forma de exclusión. Desde esta perspectiva, incorporar el marco del DUA en educación, es un reto inaplazable. Un aporte estratégico a esta perspectiva de la inclusión proviene también de los avances científicos y tecnológicos: de los resultados en el estudio del sistema nervioso surge la necesidad de abordar su plasticidad y las repercusiones que ello tiene en las prácticas educativas inclusivas, y de las evidencias de que un empleo competente de las tecnologías ofrece una oportunidad para promover estrategias didácticas en beneficio de todos, sin excepciones. El artículo propone alimentar una reflexión multidimensional sobre el enfoque de educación inclusiva abordando tanto los principios y valores sociopolíticos y culturales, como las perspectivas de diseño pedagógico-curricular y de las herramientas tecnológicas que hoy pueden representar recursos estratégicos

Inclusion, Dyslexia, Emotional State and Learning: Perceptions of Ibero-American Children with Dyslexia and Their Parents during the COVID-19 Lockdown

The COVID-19 pandemic has transformed educational processes. This has had major consequences for students and, in particular, for those with special education needs. Dyslexic students suffer from widespread educational and legal invisibility, and information on their situation and that of their families during this health crisis is lacking. This article presents the results of an exploratory study based on two online surveys taken by parents (n = 327) and children with dyslexia (n = 203) through the Spanish Dyslexia Federation (acronym in Spanish “FEDIS”), the Dyslexia and Family Association (acronym in Spanish “DISFAM”), and the Ibero-American Organisation for Specific Learning Difficulties (acronym in Spanish “OIDEA”). Data were collected in May–July 2020. The results offer a comprehensive viewpoint (family and children) on the aspects that have helped and hindered learning, such as teacher and family support, emotional state, use of ICT, and the importance of the voluntary/association network. The study provides evidence of how lockdown and school closures have created additional difficulties for learning but also how certain educational processes have been bolstered with the support of technological resources that should serve as benchmarks for education policy and classroom practice

Contributions of futures studies to education: A systematic review

Futures studies offer a framework of ideas and guidelines that allow us to develop more productive images of the future and ways of working with it. Despite several efforts to translate this approach to different educational contexts, it is still a field under development. The main objective of this article is to present and discuss the latest international academic developments and contributions of futures studies to education. For this purpose, we conducted a systematic review of the literature using the Web of Science and Scopus databases. We considered articles published between 2012 and 2022. We started with 437 articles and after the application of the exclusion criteria, this number was reduced to 50 articles that were directly related to educational issues. The findings show that the literature included specific educational methodologies, a balance between theoretical and empirical publications, a focus on specialised journals and countries and that multidisciplinarity in education was not common with subjects outside social sciences. Moreover, we found that the predictive approach and negative perspectives were not present. We conclude that futures literacy is a key element to bringing together ideas related to futures studies in education, that futures studies contribute to changing the way of working with and conceptualising the future in education, and that they promote transformative movements

Description Of An Animal Model Of Acute Cardiac Failure: In Vivo Experiments In Sheep

The purposes of this work were to, a) describe an acute animal model of severe cardiac failure induced by high doses of halothane, b) ana- lyze the effects of these overdoses of halothane on ar- terial wall dynamics and c) characterize the cardi- ovascular effects of halothane through the autonomic nervous system. Measurements were performed in six sheep before and after halothane administration (4%). A significative decrease was observed in mean aortic flow (P<0.05) and diameter (P<0.01) in heart failure with respect to control state (from 2.64±0.95 L.min-1 and 17.32±1.86 mm to 1.69±0.58 L.min-1 and 15.33±1.71 mm; respectively). A significantly de- crease was observed in mean (P<0.005), systolic (P<0.01) and diastolic (P<0.005) aortic pressure in heart failure (from 85.90±19.49 mmHg, 93.52±18.07 mmHg and 78.86±20.12 mmHg to 49.12±21.77 mmHg, 55.54±20.71 mmHg and 43.48±21.21 mmHg; respectively). Heart rate in control group (127.73±11.20 bpm) was significantly (P<0.05) higher than that observed in heart failure (107.15±13.53 bpm).Fil: Cabrera Fischer, Edmundo Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; ArgentinaFil: Camus, Juan Manuel. Universidad de Mendoza; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Barmak, Walter. Universidad Favaloro; ArgentinaFil: Risk, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Diaz, Alberto Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires; ArgentinaFil: De Forteza, E.. Universidad Favaloro; Argentin

Description Of An Animal Model Of Acute Cardiac Failure: In Vivo Experiments In Sheep

The purposes of this work were to, a) describe an acute animal model of severe cardiac failure induced by high doses of halothane, b) ana- lyze the effects of these overdoses of halothane on ar- terial wall dynamics and c) characterize the cardi- ovascular effects of halothane through the autonomic nervous system. Measurements were performed in six sheep before and after halothane administration (4%). A significative decrease was observed in mean aortic flow (P<0.05) and diameter (P<0.01) in heart failure with respect to control state (from 2.64±0.95 L.min-1 and 17.32±1.86 mm to 1.69±0.58 L.min-1 and 15.33±1.71 mm; respectively). A significantly de- crease was observed in mean (P<0.005), systolic (P<0.01) and diastolic (P<0.005) aortic pressure in heart failure (from 85.90±19.49 mmHg, 93.52±18.07 mmHg and 78.86±20.12 mmHg to 49.12±21.77 mmHg, 55.54±20.71 mmHg and 43.48±21.21 mmHg; respectively). Heart rate in control group (127.73±11.20 bpm) was significantly (P<0.05) higher than that observed in heart failure (107.15±13.53 bpm).Fil: Cabrera Fischer, Edmundo Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Favaloro; ArgentinaFil: Camus, Juan Manuel. Universidad de Mendoza; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Barmak, Walter. Universidad Favaloro; ArgentinaFil: Risk, Marcelo. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Diaz, Alberto Alejandro. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires; ArgentinaFil: De Forteza, E.. Universidad Favaloro; Argentin

Family History and Breast Cancer Hormone Receptor Status in a Spanish Cohort

Breast cancer is a heterogenous disease that impacts racial/ethnic groups differently. Differences in genetic composition, lifestyles, reproductive factors, or environmental exposures may contribute to the differential presentation of breast cancer among Hispanic women.A population-based study was conducted in the city of Santiago de Compostela, Spain. A total of 645 women diagnosed with operable invasive breast cancer between 1992 and 2005 participated in the study. Data on demographics, breast cancer risk factors, and clinico-pathological characteristics of the tumors were collected. Hormone receptor negative tumors were compared with hormone receptor postive tumors on their clinico-pathological characteristics as well as risk factor profiles.Among the 645 breast cancer patients, 78% were estrogen receptor-positive (ER+) or progesterone receptor-positive (PR+), and 22% were ER−&PR−. Women with a family history of breast cancer were more likely to have ER−&PR− tumors than women without a family history (Odds ratio, 1.43; 95% confidence interval, 0.91–2.26). This association was limited to cancers diagnosed before age 50 (Odds ratio, 2.79; 95% confidence interval, 1.34–5.81).An increased proportion of ER−&PR− breast cancer was observed among younger Spanish women with a family history of the disease

Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome : Insights from the LUNG SAFE study

Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≥ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073publishersversionPeer reviewe