321 research outputs found
The role of multiple marks in epigenetic silencing and the emergence of a stable bivalent chromatin state
- Author
- A Angel
- A Dayarian
- A Hecht
- A Kimura
- A Kristjuhan
- A Lau
- A Norris
- A Roguev
- A Saunders
- A Taddei
- A Wood
- AA Carmen
- AD Rudner
- AL Kirchmaier
- AL Kirchmaier
- AM Johansson
- AM Martin
- Anirvan M. Sengupta
- AV Probst
- B Yang
- BM Turner
- CB Millar
- D David-Rus
- D Moazed
- D Moazed
- D Nathan
- D Schbeler
- DA King
- DE Gottschling
- EA Osborne
- EA Osborne
- F Frederiks
- F Martino
- F van Leeuwen
- F Xu
- FE Pryde
- GJ Hoppe
- H Bokil
- H Fukuda
- H Renauld
- H Santos-Rosa
- HH Ng
- HH Ng
- IB Dodd
- IJ Stulemeijer
- JA Latham
- JD Lieb
- JF Chang
- JZ Kelemen
- K Martins-Taylor
- K Sarma
- K Sawada
- KG Tanner
- L Maillet
- LM Johnson
- LN Rusch
- LN Rusche
- M Altaf
- M Onishi
- M Radman-Livaja
- M Sedighi
- MA Micheelsen
- MD Shahbazian
- MF Dion
- MP Rossmann
- MS Singer
- N Dhillon
- N Suka
- N Suka
- Narendra Maheshri
- NJ Krogan
- OM Aparicio
- PB Talbert
- PD Kaufman
- RT Kamakaka
- S Enomoto
- S Imai
- S Mukhopadhyay
- S Osada
- S Strahl-Bolsinger
- S Venkatasubrahmanyam
- SK Kurdistani
- SL Berger
- SM Gasser
- SN Garcia
- Swagatam Mukhopadhyay
- T Kitada
- T Kouzarides
- T van Welsem
- V Sampath
- VM Weake
- X Bi
- Y Jin
- Y Katan-Khaykovich
- Y Zhang
- YB Schwartz
- YH Takahashi
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2013
- Field of study
We introduce and analyze a minimal model of epigenetic silencing in budding
yeast, built upon known biomolecular interactions in the system. Doing so, we
identify the epigenetic marks essential for the bistability of epigenetic
states. The model explicitly incorporates two key chromatin marks, namely H4K16
acetylation and H3K79 methylation, and explores whether the presence of
multiple marks lead to a qualitatively different systems behavior. We find that
having both modifications is important for the robustness of epigenetic
silencing. Besides the silenced and transcriptionally active fate of chromatin,
our model leads to a novel state with bivalent (i.e., both active and
silencing) marks under certain perturbations (knock-out mutations, inhibition
or enhancement of enzymatic activity). The bivalent state appears under several
perturbations and is shown to result in patchy silencing. We also show that the
titration effect, owing to a limited supply of silencing proteins, can result
in counter-intuitive responses. The design principles of the silencing system
is systematically investigated and disparate experimental observations are
assessed within a single theoretical framework. Specifically, we discuss the
behavior of Sir protein recruitment, spreading and stability of silenced
regions in commonly-studied mutants (e.g., sas2, dot1) illuminating the
controversial role of Dot1 in the systems biology of yeast silencing.Comment: Supplementary Material, 14 page
Agronomic Management of Indigenous Mycorrhizas
- Author
- A Gollotte
- A Heggo
- A Hodge
- A Liu
- A Manjunath
- A Mollier
- A Mozafar
- AD Rovira
- AE Richardson
- AI Sannazzaro
- AS El-Hassanin
- B Frey
- BAD Hetrick
- BL Allen
- C Azcón-Aguilar
- C Cordier
- C Grant
- C Kessel van
- C Plenchette
- C Plenchette
- C Val Del
- CL Boddington
- CL Boddington
- CM Hepper
- CM Hepper
- CP Chandrashekara
- D Redecker
- D Tuinen van
- DD Douds Jr
- DD Douds Jr
- DD Douds Jr
- DG Evans
- DG Evans
- DJ Read
- DP Stribley
- E George
- E Sieverding
- EA Drew
- EJ Joner
- EJ Joner
- EJ Joner
- F Borie
- F Feldmann
- F Oehl
- F Oehl
- F Rivera-Becerril
- FE Sanders
- FRS Ahmed
- G Becard
- GJ Bethlenfalvay
- GL Fairchild
- GL Fairchild
- GN Al-Karaki
- H Hauggaard-Nielsen
- H Kahiluoto
- H Kahiluoto
- H Kahiluoto
- HA Alten von
- HD Addy
- I Brito
- I Brito
- I Jakobsen
- I Ortas
- ICR Holford
- J Arihara
- J Arines
- J B Morton
- J Jansa
- J Jansa
- J Jansa
- J Scullion
- JA Menge
- JA Menge
- JB Morton
- JC Dodd
- JC Dodd
- JCC Miranda
- JD Driver
- JH Graham
- JH Graham
- JM Tisdall
- JM Tisdall
- JN Klironomos
- K Cho
- K Jayachandran
- K Tawaraya
- K Turnau
- K Yano
- KA Moyer-Henry
- KM Harinikumar
- L Corkidi
- L Galvez
- L Munkvold
- L Simon
- LK Abbott
- LK Abbott
- LK Abbott
- M Bucher
- M Franke-Snyder
- M Gollner
- M Gryndler
- M Habte
- M Niemi
- M Saito
- M Vestberg
- M Vivekanandan
- M Yamato
- MA Martins
- MA Nogueira
- MA Nogueira
- MC Rillig
- MC Rillig
- ME Gavito
- ME Gavito
- MH Miller
- MH Miller
- MH Ryan
- MJ Goss
- MJ Goss
- MM Hart
- MW Schwartz
- N Mathimaran
- NC Johnson
- NC Johnson
- NC Johnson
- NP Wellings
- NR Jordan
- NS Bolan
- P Audet
- P Gosling
- P Vandenkoornhuyse
- PD Steinberg
- PM Antunes
- PM Antunes
- PM Antunes
- PM Chalk
- R Azcón
- R Duponnois
- R Kjøller
- R Lal
- R Pandey
- R Toth
- RB Clark
- RB Clark
- RJ Cook
- RLB Black
- RM Augé
- RM Miller
- RP Schreiner
- RP Schreiner
- RPS Kesava
- RS Oliveira
- RS Thomas
- RT Koide
- RT Koide
- S Dickson
- S Gianinazzi
- S Lu
- S Mohandas
- S Subhan
- SC Vyas
- SE Smith
- SF Salem
- SF Wright
- SF Wright
- SH Burleigh
- SK Kothari
- T Karasawa
- T Karasawa
- T Karasawa
- TP McGonigle
- TP McGonigle
- TP McGonigle
- TP McGonigle
- TP McGonigle
- TP McGonigle
- TR Cavagnaro
- V Gupta
- V Göhre
- W Hendrix
- X He
- XL Li
- YG Zhu
- Z Kabir
- Z Kabir
- Z Kabir
- Z Kabir
- Z Kabir
- Z Kabir
- Z Kabir
- ZI Troeh
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2008
- Field of study
Many of the advantages conferred to plants by arbuscular mycorrhiza (AM) are associated to the ability of AM plants to explore a greater volume of soil through the extraradical mycelium. Sieverding (1991) estimates that for each centimetre of colonized root there is an increase of 15 cm3 on the volume of soil explored, this value can increase to 200 cm3 depending on the circumstances. Due to the enhancement of the volume of soil explored and the ability of the extraradical mycelium to absorb and translocate nutrients to the plant, one of the most obvious and important advantages resulting from mycorrhization is the uptake of nutrients. Among of which the ones that have immobilized forms in soil, such as P, assume particular significance. Besides this, many other benefits are recognized for AM plants (Gupta et al, 2000): water stress alleviation (Augé, 2004; Cho et al, 2006), protection from root pathogens (Graham, 2001), tolerance to toxic heavy metals and phytoremediation (Audet and Charest, 2006; Göhre and Paszkowski, 2006), tolerance to adverse conditions such as very high or low temperature, high salinity (Sannazzaro et al, 2006), high or low pH (Yano and Takaki, 2005) or better performance during transplantation shock (Subhan et al, 1998). The extraradical hyphae also stabilize soil aggregates by both enmeshing soil particles (Miller e Jastrow, 1992) and producing a glycoprotein, golmalin, which may act as a glue-like substance to adhere soil particles together (Wright and Upadhyaya, 1998).
Despite the ubiquous distribution of mycorrhizal fungi (Smith and Read, 2000) and only a relative specificity between host plants and fungal isolates (McGonigle and Fitter, 1990), the obligate nature of the symbiosis implies the establishment of a plant propagation system, either under greenhouse conditions or in vitro laboratory propagation. These techniques result in high inoculum production costs, which still remains a serious problem since they are not competitive with production costs of phosphorus fertilizer. Even if farmers understand the significance of sustainable agricultural systems, the reduction of phosphorus inputs by using AM fungal inocula alone cannot be justified except, perhaps, in the case of high value crops (Saioto and Marumoto, 2002). Nurseries, high income horticulture farmers and no-agricultural application such as rehabilitation of degraded or devegetated landscapes are examples of areas where the use of commercial inoculum is current. Another serious problem is quality of commercial available products concerning guarantee of phatogene free content, storage conditions, most effective application methods and what types to use. Besides the information provided by suppliers about its inoculum can be deceiving, as from the usually referred total counts, only a fraction may be effective for a particular plant or in specific soil conditions. Gianinazzi and Vosátka (2004) assume that progress should be made towards registration procedures that stimulate the development of the mycorrhizal industry.
Some on-farm inoculum production and application methods have been studied, allowing farmers to produce locally adapted isolates and generate a taxonomically diverse inoculum (Mohandas et al, 2004; Douds et al, 2005). However the inocula produced this way are not readily processed for mechanical application to the fields, being an obstacle to the utilization in large scale agriculture, especially row crops, moreover it would represent an additional mechanical operation with the corresponding economic and soil compaction costs.
It is well recognized that inoculation of AM fungi has a potential significance in not only sustainable crop production, but also environmental conservation. However, the status quo of inoculation is far from practical technology that can be widely used in the field. Together a further basic understanding of the biology and diversity of AM fungi is needed (Abbott at al, 1995; Saito and Marumoto, 2002).
Advances in ecology during the past decade have led to a much more detailed understanding of the potential negative consequences of species introductions and the potential for negative ecological consequences of invasions by mycorrhizal fungi is poorly understood. Schwartz et al, (2006) recommend that a careful assessment documenting the need for inoculation, and the likelihood of success, should be conducted prior to inoculation because inoculations are not universally beneficial.
Agricultural practices such as crop rotation, tillage, weed control and fertilizer apllication all produce changes in the chemical, physical and biological soil variables and affect the ecological niches available for occupancy by the soil biota, influencing in different ways the symbiosis performance and consequently the inoculum development, shaping changes and upset balance of native populations. The molecular biology tools developed in the latest years have been very important for our perception of these changes, ensuing awareness of management choice implications in AM development.
In this context, for extensive farming systems and regarding environmental and economic costs, the identification of agronomic management practices that allow controlled manipulation of the fungal community and capitalization of AM mutualistic effect making use of local inoculum, seem to be a wise option for mycorrhiza promotion and development of sustainable crop production
Measurement of the inclusive and dijet cross-sections of b-jets in pp collisions at sqrt(s) = 7 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdesselam A
- Abdinov O
- Abi B
- Abolins M
- Abramowicz H
- Abreu H
- Acerbi E
- Acharya BS
- Ackers M
- Adams DL
- Addy TN
- Adelman J
- Aderholz M
- Adomeit S
- Adragna P
- Adye T
- Aefsky S
- Aguilar-Saavedra JA
- Aharrouche M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akdogan T
- Akesson TPA
- Akimoto G
- Akimov AV
- Alam MA
- Alam MS
- Albrand S
- Aleksa M
- Aleksandrov IN
- Aleppo M
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Aliyev M
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alonso J
- Alviggi MG
- Amako K
- Amaral P
- Amelung C
- Ammosov VV
- Amorim A
- Amoros G
- Amram N
- Anastopoulos C
- Andari N
- Andeen T
- Anders CF
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M-L
- Anduaga XS
- Angerami A
- Anghinolfi F
- Anh TV
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonelli S
- Antos J
- Anulli F
- Aoun S
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Arce ATH
- Archambault JP
- Arfaoui S
- Arguin J-F
- Arik E
- Arik M
- Armbruster AJ
- Arms KE
- Armstrong SR
- Arnaez O
- Arnault C
- Artamonov A
- Artoni G
- Arutinov D
- Asai S
- Asfandiyarov R
- Ask S
- Asman B
- Asquith L
- Assamagan K
- Astbury A
- Astvatsatourov A
- Atoian G
- Aubert B
- Auerbach B
- Auge E
- Augsten K
- Aurousseau M
- Austin N
- Avramidou R
- Axen D
- Ay C
- Azuelos G
- Azuma Y
- Baak MA
- Baccaglioni G
- Bacci C
- Bach AM
- Bachacou H
- Bachas K
- Bachy G
- Backes M
- Badescu E
- Bagnaia P
- Bahinipati S
- Bai Y
- Bailey DC
- Bain T
- Baines JT
- Baker OK
- Baker S
- Banas E
- Banerjee P
- Banerjee S
- Banfi D
- Bangert A
- Bansal V
- Bansil HS
- Barak L
- Baranov SP
- Barashkou A
- Barber T
- Barberio EL
- Barberis D
- Barbero M
- Bardin DY
- Barillari T
- Barisonzi M
- Barklow T
- Barlow N
- Barnett BM
- Barnett RM
- Baroncelli A
- Barr AJ
- Barreiro F
- Barrera CO
- Barrillon P
- Bartoldus R
- Barton AE
- Bartsch D
- Bates RL
- Batkova L
- Batley JR
- Battaglia A
- Battistin M
- Battistoni G
- Bauer F
- Bawa HS
- Beare B
- Beau T
- Beauchemin PH
- Beccherle R
- Bechtle P
- Beck HP
- Beckingham M
- Becks KH
- Beddall A
- Beddall AJ
- Bednyakov VA
- Bee C
- Begel M
- Behera PK
- Beimforde M
- Belanger-Champagne C
- Belenguer MJ
- Belhorma B
- Bell PJ
- Bell WH
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- Bellagamba L
- Bellina F
- Bellomo G
- Bellomo M
- Belloni A
- Belotskiy K
- Beltramello O
- Ben Ami S
- Benary O
- Benchekroun D
- Benchouk C
- Bendel M
- Benedict BH
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- Benhammou Y
- Benjamin DP
- Benoit M
- Bensinger JR
- Benslama K
- Bentvelsen S
- Berge D
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- Biglietti M
- Bilokon H
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- Bingul A
- Bini C
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- Blanchard J-B
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- Blumenschein U
- Boaretto C
- Bobbink GJ
- Bobrovnikov VB
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- Bock R
- Boddy CR
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- Boek J
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- Bogdanchikov A
- Bogouch A
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- Boorman G
- Booth CN
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- Borisov A
- Borissov G
- Borjanovic I
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- Bos K
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- Bouhova-Thacker EV
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- Bourdarios C
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- Boveia A
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- Boyko IR
- Bozhko NI
- Bozovic-Jelisavcic I
- Braccini S
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- Branchini P
- Branco MDO
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- Bressler S
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- Brock I
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- Brubaker E
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- Bruni A
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- Buckley AG
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- Budagov IA
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- Buescher V
- Bueso XP
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- Buran T
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- Butterworth JM
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- Caccia M
- Caforio D
- Cakir IT
- Cakir O
- Calafiura P
- Calderini G
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- Calkins R
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- Carter AA
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- Carvalho J
- Casadei D
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- Castaneda-Miranda E
- Castanheira MTD
- Castillo Gimenez V
- Castillo LRF
- Castro NF
- Cataldi G
- Cataneo F
- Catinaccio A
- Catmore JR
- Cattai A
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- Cavalcanti TP
- Cavallari A
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- Cavasinni V
- Cazzato A
- Ceradini F
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- Cerri A
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- Cetin SA
- Cevenini F
- Chafaq A
- Chakraborty D
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- Chapleau B
- Chapman JD
- Chapman JW
- Chareyre E
- Charlton DG
- Chavda V
- Cheatham S
- Chekanov S
- Chekulaev SV
- Chelkov GA
- Chen H
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- Chen X
- Cheng S
- Cheong ALF
- Cheplakov A
- Chepurnov VF
- Cherkaoui El Moursli R
- Chernyatin V
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- Chizhov MV
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- Christidi IA
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- Chromek-Burckhart D
- Chu ML
- Chudoba J
- Ciapetti G
- Ciftci AK
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- Correard S
- Correia AMH
- Corriveau F
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- Czirr H
- Czyczula Z
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- da Costa JBG
- Da Rocha Gesualdi Mello A
- Da Silva PVM
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- Dallapiccola C
- Dallison SJ
- Dam M
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- De Pedis D
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- de Renstrom PAB
- de Saintignon P
- De Salvo A
- De Sanctis U
- De Santo A
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- Dedes G
- Dedovich DV
- Degenhardt J
- Dehchar M
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- Del Papa C
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- Dell'Acqua A
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- della Porta GZ
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- Delsart PA
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- Zitoun R
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- Zwalinski L
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 31/12/2010
- Field of study
The inclusive and dijet production cross-sections have been measured for jets
containing b-hadrons (b-jets) in proton-proton collisions at a centre-of-mass
energy of sqrt(s) = 7 TeV, using the ATLAS detector at the LHC. The
measurements use data corresponding to an integrated luminosity of 34 pb^-1.
The b-jets are identified using either a lifetime-based method, where secondary
decay vertices of b-hadrons in jets are reconstructed using information from
the tracking detectors, or a muon-based method where the presence of a muon is
used to identify semileptonic decays of b-hadrons inside jets. The inclusive
b-jet cross-section is measured as a function of transverse momentum in the
range 20 < pT < 400 GeV and rapidity in the range |y| < 2.1. The bbbar-dijet
cross-section is measured as a function of the dijet invariant mass in the
range 110 < m_jj < 760 GeV, the azimuthal angle difference between the two jets
and the angular variable chi in two dijet mass regions. The results are
compared with next-to-leading-order QCD predictions. Good agreement is observed
between the measured cross-sections and the predictions obtained using POWHEG +
Pythia. MC@NLO + Herwig shows good agreement with the measured bbbar-dijet
cross-section. However, it does not reproduce the measured inclusive
cross-section well, particularly for central b-jets with large transverse
momenta.Comment: 10 pages plus author list (21 pages total), 8 figures, 1 table, final
version published in European Physical Journal
Jet energy measurement with the ATLAS detector in proton-proton collisions at root s=7 TeV
- Author
- Aad G
- Abbott B
- Abdallah J
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- Zhemchugov A
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/03/2013
- Field of study
The jet energy scale and its systematic uncertainty are determined for jets measured with the ATLAS detector at the LHC in proton-proton collision data at a centre-of-mass energy of √s = 7TeV corresponding to an integrated luminosity of 38 pb-1. Jets are reconstructed with the anti-kt algorithm with distance parameters R=0. 4 or R=0. 6. Jet energy and angle corrections are determined from Monte Carlo simulations to calibrate jets with transverse momenta pT≥20 GeV and pseudorapidities {pipe}η{pipe}<4. 5. The jet energy systematic uncertainty is estimated using the single isolated hadron response measured in situ and in test-beams, exploiting the transverse momentum balance between central and forward jets in events with dijet topologies and studying systematic variations in Monte Carlo simulations. The jet energy uncertainty is less than 2. 5 % in the central calorimeter region ({pipe}η{pipe}<0. 8) for jets with 60≤pT<800 GeV, and is maximally 14 % for pT<30 GeV in the most forward region 3. 2≤{pipe}η{pipe}<4. 5. The jet energy is validated for jet transverse momenta up to 1 TeV to the level of a few percent using several in situ techniques by comparing a well-known reference such as the recoiling photon pT, the sum of the transverse momenta of tracks associated to the jet, or a system of low-pT jets recoiling against a high-pT jet. More sophisticated jet calibration schemes are presented based on calorimeter cell energy density weighting or hadronic properties of jets, aiming for an improved jet energy resolution and a reduced flavour dependence of the jet response. The systematic uncertainty of the jet energy determined from a combination of in situ techniques is consistent with the one derived from single hadron response measurements over a wide kinematic range. The nominal corrections and uncertainties are derived for isolated jets in an inclusive sample of high-pT jets. Special cases such as event topologies with close-by jets, or selections of samples with an enhanced content of jets originating from light quarks, heavy quarks or gluons are also discussed and the corresponding uncertainties are determined. © 2013 CERN for the benefit of the ATLAS collaboration
Observation of associated near-side and away-side long-range correlations in √sNN=5.02 TeV proton-lead collisions with the ATLAS detector
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- Schnoor U
- Schoeffel L
- Schoening A
- Schorlemmer AL
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- Schouten D
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- Schram M
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- Schultes J
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- Schulz H
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- Schune P
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- Schwemling P
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- Schäfer U
- Sciacca FG
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- Sciolla G
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- Searcy J
- Sedov G
- Sedykh E
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- Sekhniaidze G
- Sekula SJ
- Selbach KE
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- Shamim M
- Shan LY
- Shank JT
- Shao QT
- Shapiro M
- Shatalov PB
- Shaw K
- Sherwood P
- Shimizu S
- Shimojima M
- Shin T
- Shiyakova M
- Shmeleva A
- Shochet MJ
- Short D
- Shrestha S
- Shulga E
- Shupe MA
- Sicho P
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- Siragusa G
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- Sivoklokov SY
- Sjursen TB
- Sjölin J
- Skinnari LA
- Skottowe HP
- Skovpen K
- Skubic P
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- Slavicek T
- Sliwa K
- Smakhtin V
- Smart BH
- Smestad L
- Smirnov SY
- Smirnov Y
- Smirnova LN
- Smirnova O
- Smith BC
- Smith KM
- Smizanska M
- Smolek K
- Snesarev AA
- Snidero G
- Snow J
- Snow SW
- Snyder S
- Sobie R
- Sodomka J
- Soffer A
- Soh DA
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- Soldatov EY
- Soldevila U
- Solfaroli Camillocci E
- Solodkov AA
- Solovyanov OV
- Solovyev V
- Soni N
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- Spanò F
- Spighi R
- Spigo G
- Spiwoks R
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- Stanitzki MM
- Stapnes S
- Starchenko EA
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- Staroba P
- Starovoitov P
- Staszewski R
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- Steinberg P
- Stekl I
- Stelzer B
- Stelzer HJ
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- Strandberg S
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- Ströhmer R
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- Subramaniam R
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- Sundermann JE
- Suruliz K
- Susinno G
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- Suzuki Y
- Suzuki Y
- Svatos M
- Swedish S
- Swiatlowski M
- Sykora I
- Sykora T
- Sánchez J
- Ta D
- Tackmann K
- Taffard A
- Tafirout R
- Taiblum N
- Takahashi Y
- Takai H
- Takashima R
- Takeda H
- Takeshita T
- Takubo Y
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- Talyshev A
- Tam JY
- Tamsett MC
- Tan KG
- Tanaka J
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- Tanasijczuk AJ
- Tani K
- Tannoury N
- Tapprogge S
- Tardif D
- Tarem S
- Tarrade F
- Tartarelli GF
- Tas P
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- Tayalati Y
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- Teixeira-Dias P
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- Testa M
- Teuscher RJ
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- Theveneaux-Pelzer T
- Thoma S
- Thomas JP
- Thompson AS
- Thompson EN
- Thompson PD
- Thompson PD
- Thomsen LA
- Thomson E
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- Thong WM
- Thun RP
- Tian F
- Tibbetts MJ
- Tic T
- Tikhomirov VO
- Tikhonov YA
- Timoshenko S
- Tiouchichine E
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- Tisserant S
- Todorov T
- Todorova-Nova S
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- Tojo J
- Tokushuku K
- Tokár S
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- Tomlinson L
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- Tompkins L
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- Tonoyan A
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- Torrence E
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- Trzebinski M
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- Tsiareshka PV
- Tsionou D
- Tsipolitis G
- Tsiskaridze S
- Tsiskaridze V
- Tskhadadze EG
- Tsukerman II
- Tsulaia V
- Tsung JW
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- Tsybychev D
- Tua A
- Tudorache A
- Tudorache V
- Tuggle JM
- Turala M
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- Turk Cakir I
- Turra R
- Tuts PM
- Tykhonov A
- Tylmad M
- Tyndel M
- Tzanakos G
- Uchida K
- Ueda I
- Ueno R
- Ughetto M
- Ugland M
- Uhlenbrock M
- Ukegawa F
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- Undrus A
- Unel G
- Ungaro FC
- Unno Y
- Urbaniec D
- Urquijo P
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- Vachon B
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- Valencic N
- Valentinetti S
- Valero A
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- Valladolid Gallego E
- Vallecorsa S
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- van der Geer R
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- van der Poel E
- van der Ster D
- van Eldik N
- van Gemmeren P
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- van Vulpen I
- Vanadia M
- Vandelli W
- Vaniachine A
- Vankov P
- Vannucci F
- Vari R
- Varnes EW
- Varol T
- Varouchas D
- Vartapetian A
- Varvell KE
- Vassilakopoulos VI
- Vazeille F
- Vazquez Schroeder T
- Veloso F
- Veneziano S
- Ventura A
- Ventura D
- Venturi M
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- Vercesi V
- Verducci M
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- Vermeulen JC
- Vest A
- Vetterli MC
- Vichou I
- Vickey Boeriu OE
- Vickey T
- Viehhauser GH
- Viel S
- Villa M
- Villaplana Perez M
- Vilucchi E
- Vincter MG
- Vinek E
- Vinogradov VB
- Virzi J
- Vitells O
- Viti M
- Vivarelli I
- Vives Vaque F
- Vlachos S
- Vladoiu D
- Vlasak M
- Vogel A
- Vokac P
- Volpi G
- Volpi M
- Volpini G
- von der Schmitt H
- von Radziewski H
- von Toerne E
- Vorobel V
- Vorwerk V
- Vos M
- Voss R
- Vossebeld JH
- Vranjes Milosavljevic M
- Vranjes N
- Vrba V
- Vreeswijk M
- Vu Anh T
- Vuillermet R
- Vukotic I
- Vykydal Z
- Wagner P
- Wagner W
- Wahlen H
- Wahrmund S
- Wakabayashi J
- Walch S
- Walder J
- Walker R
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- Warburton A
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- Wardrope DR
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- Washbrook A
- Wasicki C
- Watanabe I
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- Waugh BM
- Weber MS
- Webster JS
- Weidberg AR
- Weigell P
- Weingarten J
- Weiser C
- Wells PS
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- Wendland D
- Weng Z
- Wengler T
- Wenig S
- Wermes N
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- Werner P
- Werth M
- Wessels M
- Wetter J
- Weydert C
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- Wiedenmann W
- Wielers M
- Wienemann P
- Wiglesworth C
- Wiik-Fuchs LA
- Wijeratne PA
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- Wildt MA
- Wilhelm I
- Wilkens HG
- Will JZ
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- Willis W
- Willocq S
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- Wilson JA
- Wilson MG
- Wingerter-Seez I
- Winkelmann S
- Winklmeier F
- Wittgen M
- Wittig T
- Wittkowski J
- Wollstadt SJ
- Wolter MW
- Wolters H
- Wong WC
- Wooden G
- Wosiek BK
- Wotschack J
- Woudstra MJ
- Wozniak KW
- Wraight K
- Wright M
- Wrona B
- Wu SL
- Wu X
- Wu Y
- Wulf E
- Wynne BM
- Xella S
- Xiao M
- Xie S
- Xu C
- Xu D
- Xu L
- Yabsley B
- Yacoob S
- Yamada M
- Yamaguchi H
- Yamamoto A
- Yamamoto K
- Yamamoto S
- Yamamura T
- Yamanaka T
- Yamauchi K
- Yamazaki T
- Yamazaki Y
- Yan Z
- Yang H
- Yang H
- Yang UK
- Yang Y
- Yang Z
- Yanush S
- Yao L
- Yasu Y
- Yatsenko E
- Ye J
- Ye S
- Yen AL
- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Yoshihara K
- Young C
- Young CJ
- Youssef S
- Yu D
- Yu DR
- Yu J
- Yu J
- Yuan L
- Yurkewicz A
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zambito S
- Zanello L
- Zanzi D
- Zaytsev A
- Zeitnitz C
- Zeman M
- Zemla A
- Zenin O
- Zeniš T
- Zerwas D
- Zevi Della Porta G
- Zhang D
- Zhang H
- Zhang J
- Zhang L
- Zhang X
- Zhang Z
- Zhao L
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zibell A
- Zieminska D
- Zimin NI
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zitoun R
- Zivković L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- Zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- American Physical Society
- Publication date
- 01/01/2012
- Field of study
Two-particle correlations in relative azimuthal angle (Δϕ) and pseudorapidity (Δη) are measured in √sNN=5.02 TeV p+Pb collisions using the ATLAS detector at the LHC. The measurements are performed using approximately 1 μb-1 of data as a function of transverse momentum (pT) and the transverse energy (ΣETPb) summed over 3.1<η<4.9 in the direction of the Pb beam. The correlation function, constructed from charged particles, exhibits a long-range (2<|Δη|<5) “near-side” (Δϕ∼0) correlation that grows rapidly with increasing ΣETPb. A long-range “away-side” (Δϕ∼π) correlation, obtained by subtracting the expected contributions from recoiling dijets and other sources estimated using events with small ΣETPb, is found to match the near-side correlation in magnitude, shape (in Δη and Δϕ) and ΣETPb dependence. The resultant Δϕ correlation is approximately symmetric about π/2, and is consistent with a dominant cos2Δϕ modulation for all ΣETPb ranges and particle pT
Search for R-parity-violating supersymmetry in events with four or more leptons in sqrt(s) =7 TeV pp collisions with the ATLAS detector
- Author
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- Abajyan T
- Abbott B
- Abdallah J
- Khalek SA
- Abdelalim AA
- Abdinov O
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- Yilmaz M
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- della Porta GZ
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- Zhemchugov A
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- Zibell A
- Zieminska D
- Zimin NI
- Zimmermann R
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- Zimmermann S
- Ziolkowski M
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- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Collaboration ATLAS
- Publication venue
- Springer Verlag
- Publication date
- 01/01/2008
- Field of study
A search for new phenomena in final states with four or more leptons (electrons or muons) is presented. The analysis is based on 4.7 fb−1 of s=7TeV proton-proton collisions delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in two signal regions: one that requires moderate values of missing transverse momentum and another that requires large effective mass. The results are interpreted in a simplified model of R-parity-violating supersymmetry in which a 95% CL exclusion region is set for charged wino masses up to 540 GeV. In an R-parity-violating MSUGRA/CMSSM model, values of m 1/2 up to 820 GeV are excluded for 10 < tan β < 40
Search for high-mass resonances decaying to dilepton final states in pp collisions at s√=7 TeV with the ATLAS detector
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- Yanush S
- Yao L
- Yao Y
- Yasu Y
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- Yildiz HD
- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Yoshihara K
- Young C
- Young CJ
- Youssef S
- Yu D
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- Yu J
- Yu J
- Yuan L
- Yurkewicz A
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zajacova Z
- Zanello L
- Zanzi D
- Zaytsev A
- Zeitnitz C
- Zeman M
- Zemla A
- Zendler C
- Zenin O
- Zenis T
- Zerwas D
- Zhang D
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- Zhang Z
- Zhao L
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
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- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zibell A
- Zieminska D
- Zimin NI
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- Springer
- Publication date
- 01/01/2012
- Field of study
The ATLAS detector at the Large Hadron Collider is used to search for high-mass resonances decaying to an electron-positron pair or a muon-antimuon pair. The search is sensitive to heavy neutral Z′ gauge bosons, Randall-Sundrum gravitons, Z * bosons, techni-mesons, Kaluza-Klein Z/γ bosons, and bosons predicted by Torsion models. Results are presented based on an analysis of pp collisions at a center-of-mass energy of 7 TeV corresponding to an integrated luminosity of 4.9 fb−1 in the e + e − channel and 5.0 fb−1 in the μ + μ −channel. A Z ′ boson with Standard Model-like couplings is excluded at 95 % confidence level for masses below 2.22 TeV. A Randall-Sundrum graviton with coupling k/MPl=0.1 is excluded at 95 % confidence level for masses below 2.16 TeV. Limits on the other models are also presented, including Technicolor and Minimal Z′ Models
Search for the neutral Higgs bosons of the minimal supersymmetric standard model in pp collisions at root s=7 TeV with the ATLAS detector
- Author
- Aad G
- Abajyan T
- Abbott B
- Abdallah J
- Abdelalim AA
- Abdinov O
- Abi B
- Abolins M
- AbouZeid OS
- Abramowicz H
- Abreu H
- Acharya BS
- Adam ER
- Adamczyk L
- Adams DL
- Addy TN
- Adelman J
- Adomeit S
- Adragna P
- Adye T
- Aesky S
- Agar-Savedra JA
- Agustoni M
- Ahlen SP
- Ahles F
- Ahmad A
- Ahsan M
- Aielli G
- Akesson TPA
- Akimoto G
- Akimov AV
- Alam MA
- Albert J
- Albrand S
- Aleksa M
- Aleksandrov IN
- Alessandria F
- Alexa C
- Alexander G
- Alexandre G
- Alexopoulos T
- Alhroob M
- Aliev M
- Alimonti G
- Alison J
- Allbrooke BMM
- Allison LJ
- Allport PP
- Allwood-Spiers SE
- Almenar CC
- Almond J
- Aloisio A
- Alon R
- Alonso A
- Alonso F
- Altheimer A
- Alviggi MG
- Amako K
- Amelung C
- Ammosov VV
- Amor Dos Santos SP
- Amorim A
- Amoroso S
- Amram N
- Anastopoulos C
- Ancu LS
- Andari N
- Andeen T
- Anders CF
- Anders G
- Anderson KJ
- Andreazza A
- Andrei V
- Andrieux M-L
- Anduaga XS
- Angelidakis S
- Anger P
- Angerami A
- Anghinolfi F
- Anh TV
- Anisenkov A
- Anjos N
- Annovi A
- Antonaki A
- Antonelli M
- Antonov A
- Antos J
- Anulli F
- Aoki M
- Aoun S
- Apolle R
- Arabidze G
- Aracena I
- Arai Y
- Aranda CP
- Arce ATH
- Arfaoui S
- Arguin J-F
- Argyropoulos S
- Arik E
- Arik M
- Armbruster AJ
- Arnaez O
- Arnal V
- Artamonov A
- Artoni G
- Arutinov D
- Asai S
- Ask S
- Asman B
- Asquith L
- Assamagan K
- Astbury A
- Atkinson M
- Aubert B
- Auge E
- Augsten K
- Aurousseau M
- Avolio G
- Axen A
- Azuelos G
- Azuma Y
- Baak MA
- Baccaglioni G
- Bacci C
- Bach AM
- Bachacou H
- Bachas K
- Backes M
- Backhaus M
- Badescu E
- Bagnaia P
- Bai Y
- Bailey DC
- Bain T
- Baines JT
- Baker OK
- Baker S
- Balek P
- Banas E
- Banerjee P
- Banerjee S
- Banfi D
- Bangert A
- Bansal V
- Bansil HS
- Barak L
- Baranov SP
- Barber T
- Barberio EL
- Barberis D
- Barbero N
- Bardin DY
- Barillari T
- Barisonzi M
- Barklow T
- Barlow N
- Barnett BM
- Barnett RM
- Barojas CAC
- Baroncelli A
- Barone G
- Barr AJ
- Barreiro F
- Barrera CO
- Bartoldus R
- Barton AE
- Bartsch V
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- Uchida K
- Ueda I
- Ueno R
- Ughetto N
- Ugland M
- Uhlenbrock M
- Ukegawa F
- Unal G
- Undrus A
- Unel G
- Unno Y
- Urbaniec D
- Urquijo P
- Usai G
- Vacavant L
- Vacek V
- Vachon B
- Vahsen S
- Valentinetti S
- Valero A
- Valery L
- Valkar S
- Vallecorsa S
- Van Berg R
- Van der Deij PC
- van der Geer R
- van der Graaf H
- Van der Leeuw R
- van der Poel E
- van der Ster D
- van Eldik N
- van Gemmeren P
- van Huysduynen LH
- Van Nieuwkoop J
- Van Vulpen I
- Vanadia M
- Vandelli W
- Vaniachine A
- Vankov P
- Vannucci F
- Vaque FV
- Vari R
- Varnes EW
- Varol T
- Varouchas D
- Vartapetian A
- Varvell KE
- Vassilakopoulos VI
- Vazeille F
- Vazquez JGP
- Vegni G
- Veillet JJ
- Veloso F
- Veness R
- Veneziano S
- Ventura A
- Ventura D
- Venturi M
- Venturi N
- Vercesi V
- Verducci M
- Verkerke W
- Vermeulen JC
- Vest A
- Vetterli MC
- Vickey T
- Viehhauser GHA
- Viehou I
- Viel S
- Villa M
- Vilucchi E
- Vincter MG
- Vinek E
- Vinogradov VB
- Virchaux M
- Virzi J
- Vitells O
- Viti M
- Vivarelli I
- Vlachos S
- Vladoiu D
- Vlasak M
- Vogel A
- Vokac P
- Volpi G
- Volpi M
- Volpini G
- von der Schmitt H
- von Radziewski H
- von Toerne E
- Vorobel V
- Vorwerk V
- Vos M
- Voss R
- Vossebeld JH
- Vranjes N
- Vrba V
- Vreeswijk M
- Vuillermet R
- Vukotic I
- Wagner P
- Wagner W
- Wahlen H
- Wahrmund S
- Wakabayashi J
- Walch S
- Walder J
- Walker R
- Walkowiak W
- Wall R
- Waller P
- Walsh B
- Wang C
- Wang H
- Wang H
- Wang J
- Wang J
- Wang R
- Wang SM
- Wang T
- Warburton A
- Ward CP
- Wardrope DR
- Warsinsky M
- Washbrook A
- Wasicki C
- Watanabe I
- Watkins PM
- Watson AT
- Watson IJ
- Watson MF
- Watts G
- Watts S
- Waugh AT
- Waugh BM
- Weber MS
- Webster JS
- Weidberg AR
- Weigell P
- Weingarten J
- Weiser C
- Wells PS
- Wenaus T
- Wendland D
- Weng Z
- Wengler T
- Wenig S
- Wermes N
- Werner M
- Werner P
- Werth M
- Wessels M
- Wetter J
- Weydert C
- Whalen K
- White A
- White MJ
- White S
- Whitehead SR
- Whiteson D
- Whittington D
- Wicke D
- Wickens FJ
- Wiedenmann W
- Wielers M
- Wienemann P
- Wiglesworth C
- Wiik-Fuchs LAM
- Wijeratne PA
- Wildauer A
- Wildt MA
- Wilhelm I
- Wilkens HG
- Will JZ
- Williams E
- Williams HH
- Williams S
- Willis W
- Willocq S
- Wilson A
- Wilson JA
- Wilson MG
- Wingerter-Seez I
- Winkelmann S
- Winklmeier F
- Wittgen M
- Wollstadt SJ
- Wolter MW
- Wolters H
- Wong WC
- Wooden G
- Wosiek BK
- Wotschack J
- Woudstra MJ
- Wozniak KW
- Wraight K
- Wright M
- Wrona B
- Wu SL
- Wu X
- Wu Y
- Wulf E
- Wynne BM
- Xella S
- Xiao M
- Xie S
- Xu C
- Xu D
- Xu L
- Yabsley B
- Yacoob S
- Yagci KD
- Yamada N
- Yamaguchi H
- Yamamoto A
- Yamamoto K
- Yamamoto S
- Yamamura T
- Yamanaka T
- Yamauchi K
- Yamazaki T
- Yamazaki Y
- Yan Z
- Yang H
- Yang H
- Yang UK
- Yang Y
- Yang Z
- Yanush S
- Yao L
- Yasu Y
- Yatsenko E
- Ye J
- Ye S
- Yen AL
- Yilmaz M
- Yoosoofmiya R
- Yorita K
- Yoshida R
- Yoshihara K
- Young C
- Young CJ
- Youssef S
- Yu D
- Yu DR
- Yu J
- Yu J
- Yuan L
- Yurkewicz A
- Zabinski B
- Zaidan R
- Zaitsev AM
- Zanello L
- Zanzi D
- Zaytsev A
- Zeitnitz C
- Zeman M
- Zemla A
- Zenin O
- Zenis T
- Zerwas D
- Zhang D
- Zhang H
- Zhang J
- Zhang X
- Zhang Z
- Zhao L
- Zhao Z
- Zhemchugov A
- Zhong J
- Zhou B
- Zhou N
- Zhou Y
- Zhu CG
- Zhu H
- Zhu J
- Zhu Y
- Zhuang X
- Zhuravlov V
- Zibell A
- Zieminska D
- Zimin NI
- Zimmermann R
- Zimmermann S
- Zimmermann S
- Zinonos Z
- Ziolkowski M
- Zitoun R
- Zivkovic L
- Zmouchko VV
- Zobernig G
- Zoccoli A
- zur Nedden M
- Zutshi V
- Zwalinski L
- Publication venue
- Publication date
- 01/02/2013
- Field of study
A search for neutral Higgs bosons of the Minimal Supersymmetric Standard Model (MSSM) is reported. The analysis is based on a sample of proton-proton collisions at a centre-of-mass energy of 7TeV recorded with the ATLAS detector at the Large Hadron Collider. The data were recorded in 2011 and correspond to an integrated luminosity of 4.7 fb-1 to 4.8 fb-1. Higgs boson decays into oppositely-charged muon or τ lepton pairs are considered for final states requiring either the presence or absence of b-jets. No statistically significant excess over the expected background is observed and exclusion limits at the 95% confidence level are derived. The exclusion limits are for the production cross-section of a generic neutral Higgs boson, φ, as a function of the Higgs boson mass and for h/A/H production in the MSSM as a function of the parameters mA and tan β in the mhmax scenario for mA in the range of 90GeV to 500 GeV. Copyright CERN
Biological variability dominates and influences analytical variance in HPLC-ECD studies of the human plasma metabolome
- Author
- A Aitio
- AF Subar
- Bruce S Kristal
- BS Kristal
- BS Kristal
- BS Kristal
- C Ricos
- C Ricos
- CG Fraser
- CP Wild
- D Midthune
- EE Calle
- FE Thompson
- FE Thompson
- GG Harrigan
- H Crews
- H Okubo
- H Shi
- H Shi
- H Shi
- H Shi
- HM Blanck
- I Dalle-Donne
- J Trabulsi
- JA Milner
- JA Tooze
- JB German
- JB German
- JK Yao
- JR Marshall
- JR Marshall
- KE Vigneau-Callahan
- KS Solanky
- KW Dodd
- L Lissner
- M Baker
- MB Livingstone
- MK Tuxen
- N Potischman
- N Potischman
- NM McKeown
- O Fiehn
- O Fiehn
- PE Milbury
- PH Petersen
- R Goodacre
- R Saracci
- RJ Bino
- RJ Lamers
- RL Prentice
- S Clark
- S Clark
- S Vaidyanathan
- SA Bingham
- SE Hankinson
- SM Watkins
- SM Watkins
- Susan E Hankinson
- T Key
- U Paolucci
- U Paolucci
- W Weckwerth
- Walter C Willett
- Wayne R Matson
- WC Willett
- WC Willett
- WR Matson
- WR Matson
- WR Matson
- Y Noguchi
- Y Shurubor
- Yevgeniya I Shurubor
- YI Shurubor
- Publication venue
- BioMed Central
- Publication date
- 01/01/2007
- Field of study
<p>Abstract</p> <p>Background</p> <p>Biomarker-based assessments of biological samples are widespread in clinical, pre-clinical, and epidemiological investigations. We previously developed serum metabolomic profiles assessed by HPLC-separations coupled with coulometric array detection that can accurately identify <it>ad libitum </it>fed and caloric-restricted rats. These profiles are being adapted for human epidemiology studies, given the importance of energy balance in human disease.</p> <p>Methods</p> <p>Human plasma samples were biochemically analyzed using HPLC separations coupled with coulometric electrode array detection.</p> <p>Results</p> <p>We identified these markers/metabolites in human plasma, and then used them to determine which human samples represent blinded duplicates with 100% accuracy (N = 30 of 30). At least 47 of 61 metabolites tested were sufficiently stable for use even after 48 hours of exposure to shipping conditions. Stability of some metabolites differed between individuals (N = 10 at 0, 24, and 48 hours), suggesting the influence of some biological factors on parameters normally considered as analytical.</p> <p>Conclusion</p> <p>Overall analytical precision (mean median CV, ~9%) and total between-person variation (median CV, ~50–70%) appear well suited to enable use of metabolomics markers in human clinical trials and epidemiological studies, including studies of the effect of caloric intake and balance on long-term cancer risk.</p
A multimeasure approach to investigating affective appraisal of social information in Williams syndrome
- Author
- A Gosch
- A Kaufman
- A Meyer-Lindenberg
- A Meyer-Lindenberg
- AE John
- AK Ewart
- Alex B. Fine
- B Haas
- BM Paul
- BP Klein-Tasman
- C Gagliardi
- C Mervis
- C Morris
- C Stinton
- CB Mervis
- CF Norbury
- D Mobbs
- D Plesa Skwerer
- D Plesa Skwerer
- D Plesa Skwerer
- D Plesa Skwerer
- Daniela Plesa Skwerer
- DM Riby
- DM Riby
- E Frigerio
- E Granholm
- E Semel
- EH Hess
- EM Dykens
- Emily Ammerman
- F Shic
- FE Rose
- H Tager-Flusberg
- H Tager-Flusberg
- Helen Tager-Flusberg
- HF Dodd
- IE Lowenfeld
- JE LeDoux
- JR Korenberg
- KE Muñoz
- Lucia Ciciolla
- M Porter
- MA Martens
- MA Porter
- Marie-Christine André
- MP Janisse
- NJ Sasson
- P Howlin
- R Adolphs
- R Adolphs
- S Kasthurirangan
- TF Doyle
- U Bellugi
- U Bellugi
- W Jones
- WL Libby Jr
- Publication venue
- Springer US
- Publication date
- 01/01/2011
- Field of study
People with Williams syndrome (WS) have been consistently described as showing heightened sociability, gregariousness, and interest in people, in conjunction with an uneven cognitive profile and mild to moderate intellectual or learning disability. To explore the mechanisms underlying this unusual social–behavioral phenotype, we investigated whether individuals with WS show an atypical appraisal style and autonomic responsiveness to emotionally laden images with social or nonsocial content. Adolescents and adults with WS were compared to chronological age-matched and nonverbal mental age-matched groups in their responses to positive and negative images with or without social content, using measures of self-selected viewing time (SSVT), autonomic arousal reflected in pupil dilation measures, and likeability ratings. The participants with WS looked significantly longer at the social images compared to images without social content and had reduced arousal to the negative social images compared to the control groups. In contrast to the comparison groups, the explicit ratings of likeability in the WS group did not correlate with their SSVT; instead, they reflected an appraisal style of more extreme ratings. This distinctive pattern of viewing interest, likeability ratings, and autonomic arousal to images with social content in the WS group suggests that their heightened social drive may be related to atypical functioning of reward-related brain systems reflected in SSVT and autonomic reactivity measures, but not in explicit ratings
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