2,825 research outputs found
Dielectric mismatch and shallow donor impurities in GaN/HfO2 quantum wells
In this work we investigate electron-impurity binding energy in GaN/HfO
quantum wells. The calculation considers simultaneously all energy
contributions caused by the dielectric mismatch: (i) image self-energy (i.e.,
interaction between electron and its image charge), (ii) the direct Coulomb
interaction between the electron-impurity and (iii) the interactions among
electron and impurity image charges. The theoretical model account for the
solution of the time-dependent Schr\"odinger equation and the results shows how
the magnitude of the electron-impurity binding energy depends on the position
of impurity in the well-barrier system. The role of the large dielectric
constant in the barrier region is exposed with the comparison of the results
for GaN/HfO with those of a more typical GaN/AlN system, for two different
confinement regimes: narrow and wide quantum wells.Comment: 6 Pages, 7 figure
Desenvolvimento de tecnologias para a melhoria do sistema de criação em cativeiro do pirarucu, Arapaima gigas.
bitstream/item/86403/1/Digitalizar0144.pd
Paraoxonase 2 overexpression inhibits tumor development in a mouse model of ovarian cancer.
Ovarian cancer (OC) is most lethal malignancy among all gynecological cancer. Large bodies of evidences suggest that mitochondrial-derived ROS play a critical role in the development and progression of OC. Paraoxonase 2 (PON2) is a membrane-associated lactonase with anti-oxidant properties. PON2 deficiency aggravates mitochondrial ROS formation, systemic inflammation, and atherosclerosis. The role of PON2 in cancer development remains unknown. In this report, in human, we identified that PON2 expression is higher in early stages (but not in late stages) of OC when compared to normal tissue. Using a mouse xenograft model of OC, we demonstrate that overexpression of PON2 prevents tumor formation. Mechanistically, PON2 decreases OC cell proliferation by inhibiting insulin like growth factor-1 (IGF-1) expression and signaling. Intriguingly, PON2 reduces c-Jun-mediated transcriptional activation of IGF-1 gene by decreasing mitochondrial superoxide generation. In addition, PON2 impairs insulin like growth factor-1 receptor (IGF-1R) signaling in OC cells by altering cholesterol homeostasis, which resulted in reduced caveolin-1/IGF-1R interaction and IGF-1R phosphorylation. Taken together, we report for the first time that PON2 acts as a tumor suppressor in the early stage of OC by reducing IGF-1 production and its signaling, indicating PON2 activation might be a fruitful strategy to inhibit early stage ovarian tumor
Optimization of the transmission of observable expectation values and observable statistics in Continuous Variable Teleportation
We analyze the statistics of observables in continuous variable quantum
teleportation in the formalism of the characteristic function. We derive
expressions for average values of output state observables in particular
cumulants which are additive in terms of the input state and the resource of
teleportation. Working with Squeezed Bell-like states, which may be optimized
in a free parameter for better teleportation performance we discuss the
relation between resources optimal for fidelity and for different observable
averages. We obtain the values of the free parameter which optimize the central
momenta and cumulants up to fourth order. For the cumulants the distortion
between in and out states due to teleportation depends only on the resource. We
obtain optimal parameters for the second and fourth order cumulants which do
not depend on the squeezing of the resource. The second order central momenta
which is equal to the second order cumulants and the photon number average are
optimized by the same resource. We show that the optimal fidelity resource,
found in reference (Phys. Rev. A {\bf 76}, 022301 (2007)) to depend also on the
characteristics of input, tends for high squeezing to the resource which
optimizes the second order momenta. A similar behavior is obtained for the
resource which optimizes the photon statistics which is treated here using the
sum of the squared differences in photon probabilities of input and output
states as the distortion measure. This is interpreted to mean that the
distortions associated to second order momenta dominates the behavior of the
output state for large squeezing of the resource. Optimal fidelity and optimal
photon statistics resources are compared and is shown that for mixtures of Fock
states they are equivalent.Comment: 25 pages, 11 figure
Seleção de genitores de mandioca por meio da divergência avaliada a partir de caracteres morfo-agronômicos.
A consistent scalar-tensor cosmology for inflation, dark energy and the Hubble parameter
The authors are grateful for financial support to the Cruickshank Trust (CW), EPSRC/GG-Top (CW, JR), Omani Government (MA), Science Without Borders programme, CNPq, Brazil (DR), and STFC/CfFP (CW, AM, RB, JM). CW and AM acknowledge the hospitality of CERN, where this work was started. The University of Aberdeen and University of Edinburgh are charitable bodies registered in Scotland, with respective registration numbers SC013683 and SC005336.Peer reviewedPostprin
Efeito alelopático de Leucena (Leucaena leucocephala) sobre três espécies de plantas daninhas da cultura do milho.
Aplicação da metodologia de modelos mistos (REML/BLUP) na estimação de componentes de variância e predição de valores genéticos em pupunheira (Bactris gasipaes).
Aplicação da metodologia de modelos mistos (REML/BLUP) na estimação de componentes de variância e predição de valores genéticos em pupunheira (Bactris gasipaes).
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