24 research outputs found
Monoclonal IgM cold agglutinins with anti-Pr1d specificity in a patient with peripheral neuropathy
No full textA patient with a demyelinating sensory motor polyneuropathy secondary to IgM paraproteinaemia is reported. The paraprotein binds to the gangliosides GD1b, GT1b, GQ1b and GD3, all of which contain disialosyl groups with the sequence NeuAc α 2-8NeuAc α 2-3Gal. The paraprotein also acts as a cold agglutinin recognising the sialic-acid-dependent Pr<sub>1d</sub> antigenic determinant of the red cell membrane glycophorins. In this and in similar cases that have been reported, the coexistence of anti-Pr cold agglutinins and peripheral neuropathy suggest that they might be the causative agents of the disease
Monoclonal IgM Cold Agglutinins with Anti-Pr(1d) Specificity in a Patient with Peripheral Neuropathy
No full textA Fatal Transfusion Reaction Associated with Blood Contaminated with Pseudomonas fluorescens
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The treatment of venous thrombosis of the upper and lower limbs with “APSAC” (P-anisoylated streptokinase-plasminogen complex)
No full textEvidence-based criteria for the care and selection of blood donors, with some comments on the relationship to blood supply, and emphasis on the management of donation-induced iron depletion
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