Histological Study of the First Seven Days of Skin Wound Healing in Rats

The aim of this study was to elaborate a histological model of incisional skin wound healing in Sprague-Dawley rats. Under aseptic conditions two paravertebral full thickness skin incisions were performed on the back of 42 anesthetized male rats. Histological sections from tissue specimens were stained by hematoxylin and eosin, van Gieson, PAS + PSD, Mallory's phosphotungstic hematoxylin and azur and eosin and evaluated during the first seven days after surgery. Histological evaluation revealed that the regeneration of injured epidermis was completed five days after surgery. The inflammatory phase was recorded during the first three days of healing with the culmination of this phase between day one and day two. The beginning of the proliferative phase was dated to the first day and the peak during day five and day six. The initiation of the maturation and remodeling phase of the healing process was observed six days after wounding. At the layer of striated muscle, the centronucleated cells were described for the first time six days after surgery. The wound healing process of rat skin was histologically described during the first seven days. Results of this work can serve as an experimental model for further research using external pharmacological and physical factors (laser light, magnetic field) by which the wound healing can be favourably influenced

Lithostratigraphy of the Palaeoproterozoic Hekpoort formation (Pretoria Group, Transvaal Supergroup), South Africa

The Palaeoproterozoic Hekpoort Formation of the Pretoria Group is a lava-dominated unit that has a basin-wide extent throughout the Transvaal sub-basin of South Africa. Additional correlative units may be present in the Kanye sub-basin of Botswana. The key characteristic of the formation is its general geochemical uniformity. Volcaniclastic and other sedimentary rocks are relatively rare throughout the succession but may be dominant in some locations. Hekpoort Formation outcrops are sporadic throughout the basin and mostly occur in the form of gentle hills and valleys, mainly encircling Archaean domes and the Palaeoproterozoic Bushveld Complex (BC). The unit is exposed in the western Pretoria Group basin, sitting unconformably either on the Timeball Hill Formation or Boshoek Formation, which is lenticular there, and on top of the Boshoek Formation in the east of the basin. The unit is unconformably overlain by the Dwaalheuwel Formation. The type-locality for the Hekpoort Formation is the Hekpoort farm (504 IQ Hekpoort), ca. 60 km to the west-southwest of Pretoria. However, no stratotype has ever been proposed. A lectostratotype, i.e., the Mooikloof area in Pretoria East, that can be enhanced by two reference stratotypes are proposed herein. The Hekpoort Formation was deposited in a cratonic subaerial setting, forming a large igneous province (LIP) in which short-termed localised ponds and small braided river systems existed. It therefore forms one of the major Palaeoproterozoic magmatic events on the Kaapvaal Craton.http://sajg.geoscienceworld.orgam2021Geolog

Homological Localisation of Model Categories

One of the most useful methods for studying the stable homotopy category is localising at some spectrum E. For an arbitrary stable model category we introduce a candidate for the E–localisation of this model category. We study the properties of this new construction and relate it to some well–known categories

Seismic detection of rockslides at regional scale: examples from the Eastern Alps and feasibility of kurtosis-based event location

Seismic records can provide detailed insight into the mechanisms of gravitational mass movements. Catastrophic events that generate long-period seismic radiation have been studied in detail, and monitoring systems have been developed for applications on a very local scale. Here we demonstrate that similar techniques can also be applied to regional seismic networks, which show great potential for real-time and large-scale monitoring and analysis of rockslide activity. This paper studies 19 moderate-sized to large rockslides in the Eastern Alps that were recorded by regional seismic networks within distances of a few tens of kilometers to more than 200&thinsp;km. We develop a simple and fully automatic processing chain that detects, locates, and classifies rockslides based on vertical-component seismic records. We show that a kurtosis-based onset picker is suitable to detect the very emergent onsets of rockslide signals and to locate the rockslides within a few kilometers from the true origin using a grid search and a 1-D seismic velocity model. Automatic discrimination between rockslides and local earthquakes is possible by a combination of characteristic parameters extracted from the seismic records, such as kurtosis or maximum-to-mean amplitude ratios. We attempt to relate the amplitude of the seismic records to the documented rockslide volume and reveal a potential power law in agreement with earlier studies. Since our approach is based on simplified methods we suggest and discuss how each step of the automatic processing could be expanded and improved to achieve more detailed results in the future.</p

Groundwater ages, recharge conditions and hydrochemical evolution of a barrier island freshwater lens (Spiekeroog, Northern Germany)

Freshwater lenses below barrier islands are dynamic systems affected by changes in morphodynamic patterns, groundwater recharge and discharge. They are also vulnerable to pollution and overabstraction of groundwater. Basic knowledge on hydrogeological and hydrochemical processes of freshwater lenses is important to ensure a sustainable water management, especially when taking into account possible effects of climate change. This is the first study which gives a compact overview on the age distribution, recharge conditions and hydrochemical evolution of a barrier island freshwater lens in the southern North Sea (Spiekeroog Island, Eastfrisian Wadden Sea). Two ground- and surface water sampling campaigns were carried out in May and July 2011, supplemented by monthly precipitation sampling from July to October. 3H–3He ages, stable oxygen and hydrogen isotopes and major ion concentrations show that the freshwater lens reaches a depth of 44 mbsl, where an aquitard constrains further expansion in vertical direction. Groundwater ages are increasing from 4.4 years in 12 mbsl up to >70 years at the freshwater– saltwater interface. Stable isotope signatures reflect average local precipitation signatures. An annual recharge rate of 300–400 mm was calculated with 3H–3He data. Freshwater is primarily of Na–Ca–Mg–HCO3– and Ca–Na–HCO3–Cl type, while lowly mineralized precipitation and saltwater are of Na–Cl types. A trend towards heavier stable isotope signatures and higher electric conductivities in the shallower, younger groundwater within the freshwater lens may indicate increasing atmospheric temperatures in the last 30 years

Probing Nuclear forces beyond the drip-line using the mirror nuclei 16^{16}N and 16^{16}F

Radioactive beams of $^{14}$O and $^{15}$O were used to populate the resonant states 1/2$^+$, 5/2$^+$ and $0^-,1^-,2^-$ in the unbound $^{15}$F and $^{16}$F nuclei respectively by means of proton elastic scattering reactions in inverse kinematics. Based on their large proton spectroscopic factor values, the resonant states in $^{16}$F can be viewed as a core of $^{14}$O plus a proton in the 2s$_{1/2}$ or 1d$_{5/2}$ shell and a neutron in 1p$_{1/2}$. Experimental energies were used to derive the strength of the 2s$_{1/2}$-1p$_{1/2}$ and 1d$_{5/2}$-1p$_{1/2}$ proton-neutron interactions. It is found that the former changes by 40% compared with the mirror nucleus $^{16}$N, and the second by 10%. This apparent symmetry breaking of the nuclear force between mirror nuclei finds explanation in the role of the large coupling to the continuum for the states built on an $\ell=0$ proton configuration.Comment: 6 pages, 3 figures, 2 tables, accepted for publication as a regular article in Physical Review

New pathway to bypass the 15O waiting point

We propose the sequential reaction process $^{15}$O($p$,$\gamma)(\beta^{+}$)$^{16}$O as a new pathway to bypass of the $^{15}$O waiting point. This exotic reaction is found to have a surprisingly high cross section, approximately 10$^{10}$ times higher than the $^{15}$O($p$,$\beta^{+}$)$^{16}$O. These cross sections were calculated after precise measurements of energies and widths of the proton-unbound $^{16}$F low lying states, obtained using the H($^{15}$O,p)$^{15}$O reaction. The large $(p,\gamma)(\beta^{+})$ cross section can be understood to arise from the more efficient feeding of the low energy wing of the ground state resonance by the gamma decay. The implications of the new reaction in novae explosions and X-ray bursts are discussed.Comment: submitte

An all-solid-state laser source at 671 nm for cold atom experiments with lithium

We present an all solid-state narrow line-width laser source emitting $670\,\mathrm{mW}$ output power at $671\,\mathrm{nm}$ delivered in a diffraction-limited beam. The \linebreak source is based on a fre-quency-doubled diode-end-linebreak pumped ring laser operating on the ${^4F}_{3/2} \rightarrow {^4I}_{13/2}$ transition in Nd:YVO$_4$. By using periodically-poled po-tassium titanyl phosphate (ppKTP) in an external build-up cavity, doubling efficiencies of up to 86% are obtained. Tunability of the source over $100\,\rm GHz$ is accomplished. We demonstrate the suitability of this robust frequency-stabilized light source for laser cooling of lithium atoms. Finally a simplified design based on intra-cavity doubling is described and first results are presented

Towers and fibered products of model categories

Given a left Quillen presheaf of localized model structures, we study the homotopy limit model structure on the associated category of sections. We focus specifically on towers and fibered products of model categories. As applications we consider Postnikov towers of model categories, chromatic towers of spectra and Bousfield arithmetic squares of spectra. For spectral model categories, we show that the homotopy fiber of a stable left Bousfield localization is a stable right Bousfield localization