443 research outputs found

    ΠœΠ΅Ρ‚ΠΎΠ΄ΠΈΡ‡Π΅ΡΠΊΠΈΠ΅ основы ΠΎΡ†Π΅Π½ΠΊΠΈ качСства обслуТивания Π² туристичСском бизнСсС

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    ΠŸΡ€ΠΎΠ±Π»Π΅ΠΌΠ° опрСдСлСния качСства обслуТивания Π² туристичСском бизнСсС являСтся Π°ΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½ΠΎΠΉ, Ρ‚.ΠΊ. туристичСская Π΄Π΅ΡΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ являСтся ΠΏΡ€ΠΈΠΎΡ€ΠΈΡ‚Π΅Ρ‚Π½Ρ‹ΠΌ Π½Π°ΠΏΡ€Π°Π²Π»Π΅Π½ΠΈΠ΅ΠΌ развития Π² АР ΠšΡ€Ρ‹ΠΌ. РассмотрСна ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈΠΊΠ° опрСдСлСния качСства обслуТивания туристов с ΡƒΡ‡Π΅Ρ‚ΠΎΠΌ спСцифики функционирования туристской сфСры.ΠŸΡ€ΠΎΠ±Π»Π΅ΠΌΠ° визначСння якості обслуговування Ρƒ туристичному бізнСсі Ρ” Π°ΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½ΠΎΡŽ, Ρ‚ΠΎΠΌΡƒ Ρ‰ΠΎ туристична Π΄Ρ–ΡΠ»ΡŒΠ½Ρ–ΡΡ‚ΡŒ Ρ” ΠΏΡ€Ρ–ΠΎΡ€ΠΈΡ‚Π΅Ρ‚Π½ΠΈΠΌ напрямком Ρ€ΠΎΠ·Π²ΠΈΡ‚ΠΊΡƒ Π² АР ΠšΡ€ΠΈΠΌ. Розглянута ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈΠΊΠ° визначСння якості обслуговування туристів Π· ΡƒΠΌΠΎΠ²ΠΎΡŽ спСцифіки функціонування туристичної сфСри.The problem of quality service in the tourist's business is very actuality, because the tourist's activity is the priority directions of development in the Crimea. Given the method of definition of the quality service in the tourist's business with registration of specific tourism sphere

    Π–ΡƒΡ€Π½Π°Π» ΠΊΡ€ΠΈΠΌΡΡŒΠΊΠΈΡ… ΠΊΠ°Ρ€Π°Ρ—ΠΌΡ–Π² β€œΠ‘ΠΈΠ·Ρ‹ΠΌ йол” (β€œΠΠ°Ρˆ ΡˆΠ»ΡΡ…β€) Ρƒ світлі Ρ‚Ρ€Π°Π΄ΠΈΡ†Ρ–ΠΉ ΠΊΠ°Ρ€Π°Ρ—ΠΌΡΡŒΠΊΠΎΡ— прСси Ρ– Π½Π°Ρ†Ρ–ΠΎΠ½Π°Π»ΡŒΠ½ΠΎΡ— ΠΏΠΎΠ»Ρ–Ρ‚ΠΈΠΊΠΈ ΠšΡ€ΠΈΠΌΡΡŒΠΊΠΎΡ— АРБР

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    Π’ ΡΡ‚Π°Ρ‚ΡŒΠ΅ содСрТится описаниС караимских пСриодичСских ΠΈΠ·Π΄Π°Π½ΠΈΠΉ Π½Π°Ρ‡Π°Π»Π° Π₯Π₯ Π²Π΅ΠΊΠ°, ΠΈΡ… Ρ†Π΅Π»Π΅ΠΉ ΠΈ Π·Π°Π΄Π°Ρ‡ΠΈ, объСма, основных ΠΎΡ‚Π΄Π΅Π»ΠΎΠ², исслСдуСтся ΠΎΡ‚Ρ€Π°ΠΆΠ΅Π½ΠΈΠ΅ Π² караимской ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ΠΈΠΊΠ΅ процСссов Π½Π°Ρ†ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ ΠΊΡƒΠ»ΡŒΡ‚ΡƒΡ€Π½ΠΎΠ³ΠΎ рСнСссанса, изучаСтся связь этничСских ΠΈΠ·Π΄Π°Π½ΠΈΠΉ ΠΊΠ°Ρ€Π°ΠΈΠΌΠΎΠ² с общСствСнно-политичСской Тизнью караимской ΠΎΠ±Ρ‰ΠΈΠ½Ρ‹.Бтаття ΠΌΡ–ΡΡ‚ΠΈΡ‚ΡŒ опис ΠΊΠ°Ρ€Π°Ρ—ΠΌΡΡŒΠΊΠΈΡ… видань ΠΏΠΎΡ‡Π°Ρ‚ΠΊΡƒ Π₯Π₯ століття, Π·'ясовує Ρ—Ρ…Π½Ρ– Ρ†Ρ–Π»Ρ– Ρ– Π·Π°Π²Π΄Π°Π½-ня, обсяг, основні Ρ€ΠΎΠ·Π΄Ρ–Π»ΠΈ; дослідТує відбиття Ρƒ ΠΊΠ°Ρ€Π°Ρ—ΠΌΡΡŒΠΊΡ–ΠΉ ΠΏΠ΅Ρ€Ρ–ΠΎΠ΄ΠΈΡ†Ρ– процСсів Π½Π°Ρ†Ρ–ΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ ΠΊΡƒΠ»ΡŒΡ‚ΡƒΡ€Π½ΠΎΠ³ΠΎ рСнСсансу; Π²ΠΈΠ²Ρ‡Π°Ρ” Π·Π²'язок Π΅Ρ‚Π½Ρ–Ρ‡Π½ΠΈΡ… видань ΠΊΠ°Ρ€Π°Ρ—ΠΌΡ–Π² Ρ–Π· ΡΡƒΡΠΏΡ–Π»ΡŒΠ½ΠΎ-ΠΏΠΎΠ»Ρ–Ρ‚ΠΈΡ‡Π½ΠΈΠΌ Титтям ΠΊΠ°Ρ€Π°Ρ—ΠΌΡΡŒΠΊΠΎΡ— Π³Ρ€ΠΎΠΌΠ°Π΄ΠΈ.The article researches the Karaite mass media of the beginning of the XX century: its matters and tasks, volume, main sections, the reflection of the cultural renaissance in it and its connection with life of the Karaite community

    Epidemiology and outcome of rib fractures:a nationwide study in the Netherlands

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    Purpose Rib fractures following thoracic trauma are frequently encountered injuries and associated with a significant morbidity and mortality. The aim of this study was to provide current data on the epidemiology, in-hospital outcomes and 30-day mortality of rib fractures, and to evaluate these results for different subgroups. Methods A nationwide retrospective cohort study was performed with the use of the Dutch Trauma Registry which covers 99% of the acutely admitted Dutch trauma population. All patients aged 18 years and older admitted to the hospital between January 2015 and December 2017 with one or more rib fractures were included. Incidence rates were calculated using demographic data from the Dutch Population Register. Subgroup analyses were performed for flail chest, polytrauma, primary thoracic trauma, and elderly patients. Results A total of 14,850 patients were admitted between 2015 and 2017 with one or more rib fractures, which was 6.0% of all trauma patients. Of these, 573 (3.9%) patients had a flail chest, 4438 (29.9%) were polytrauma patients, 9273 (63.4%) were patients with primary thoracic trauma, and 6663 (44.9%) were elderly patients. The incidence rate of patients with rib fractures for the entire cohort was 29 per 100.000 person-years. The overall 30-day mortality was 6.9% (n = 1208) with higher rates observed in flail chest (11.9%), polytrauma (14.8%), and elderly patients (11.7%). The median hospital length of stay was 6 days (IQR, 3-11) and 37.3% were admitted to the intensive care unit (ICU). Conclusions Rib fractures are a relevant and frequently occurring problem among the trauma population. Subgroup analyses showed that there is a substantial heterogeneity among patients with rib fractures with considerable differences regarding the epidemiology, in-hospital outcomes, and 30-day mortality

    Metabolic syndrome in adults with autistic traits:associated psychological, behavioral, and biological factors in females and males - a PharmLines initiative

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    Background: While cardiovascular diseases is highly prevalent and an important cause of mortality in autistic adults, knowledge on their increased cardiovascular risk is limited. Hence, this study aimed to investigate psychological, behavioral, and physical factors associated with metabolic syndrome (MetS) in adults with autistic traits. Methods: In total, 17,705 adults from the Lifelines Cohort were included and categorized using Autism Spectrum Quotient-10 sum-scores. The quartiles with highest (HQ-traits-group females: n = 2,635; males: n = 1803) and lowest levels of autistic traits (LQ-traits-group, n = idem) were analyzed. Using multivariable logistic regression, the associations between MetS and (self-reported and interviewed) psychological, behavioral, and physically measured factors in these stratified groups were investigated. Results: Among females, MetS was more common in the HQ-traits-group than in the LQ-traits-group (10.0% versus 7.5%, p &lt; 0.01), while this was not the case among males (HQ-traits-group 13.8% versus LQ-traits-group 13.1%, p = 0.52). In both the female and male HQ-traits-group, the presence of MetS was associated with poorer self-reported health, less daily physical activity, and altered leukocyte counts. Conclusion: These findings underline the relevance of adequate cardiovascular prevention in adults with higher levels of autistic traits. Future research could gain more insight into the relationship between cardiovascular risk and autistic traits in females, and into tailored cardiovascular prevention.</p

    Metabolic syndrome in adults with autistic traits:associated psychological, behavioral, and biological factors in females and males - a PharmLines initiative

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    Background: While cardiovascular diseases is highly prevalent and an important cause of mortality in autistic adults, knowledge on their increased cardiovascular risk is limited. Hence, this study aimed to investigate psychological, behavioral, and physical factors associated with metabolic syndrome (MetS) in adults with autistic traits. Methods: In total, 17,705 adults from the Lifelines Cohort were included and categorized using Autism Spectrum Quotient-10 sum-scores. The quartiles with highest (HQ-traits-group females: n = 2,635; males: n = 1803) and lowest levels of autistic traits (LQ-traits-group, n = idem) were analyzed. Using multivariable logistic regression, the associations between MetS and (self-reported and interviewed) psychological, behavioral, and physically measured factors in these stratified groups were investigated. Results: Among females, MetS was more common in the HQ-traits-group than in the LQ-traits-group (10.0% versus 7.5%, p &lt; 0.01), while this was not the case among males (HQ-traits-group 13.8% versus LQ-traits-group 13.1%, p = 0.52). In both the female and male HQ-traits-group, the presence of MetS was associated with poorer self-reported health, less daily physical activity, and altered leukocyte counts. Conclusion: These findings underline the relevance of adequate cardiovascular prevention in adults with higher levels of autistic traits. Future research could gain more insight into the relationship between cardiovascular risk and autistic traits in females, and into tailored cardiovascular prevention.</p

    Epidemiology of combined clavicle and rib fractures:a systematic review

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    Purpose The aim of this systematic review was to provide an overview of the incidence of combined clavicle and rib fractures and the association between these two injuries. Methods A systematic literature search was performed in the MEDLINE, EMBASE, and CENTRAL databases on the 14(th) of August 2020. Outcome measures were incidence, hospital length of stay (HLOS), intensive care unit admission and length of stay (ILOS), duration of mechanical ventilation (DMV), mortality, chest tube duration, Constant-Murley score, union and complications. Results Seven studies with a total of 71,572 patients were included, comprising five studies on epidemiology and two studies on treatment. Among blunt chest trauma patients, 18.6% had concomitant clavicle and rib fractures. The incidence of rib fractures in polytrauma patients with clavicle fractures was 56-60.6% versus 29% in patients without clavicle fractures. Vice versa, 14-18.8% of patients with multiple rib fractures had concomitant clavicle fractures compared to 7.1% in patients without multiple rib fractures. One study reported no complications after fixation of both injuries. Another study on treatment, reported shorter ILOS and less complications among operatively versus conservatively treated patients (5.4 +/- 1.5 versus 21 +/- 13.6 days). Conclusion Clavicle fractures and rib fractures are closely related in polytrauma patients and almost a fifth of all blunt chest trauma patients sustain both injuries. Definitive conclusions could not be drawn on treatment of the combined injury. Future research should further investigate indications and benefits of operative treatment of this injury

    The effect of early broad-spectrum versus delayed narrow-spectrum antibiotic therapy on the primary cure rate of acute infection after osteosynthesis

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    Purpose: Infection near metal implants is a problem that presents challenging treatment dilemmas for physicians. The aim of this study was to analyse the efficacy of two treatment protocols for acute fracture-related infections. Methods: Seventy-one patients in two level-1 trauma centres in the Netherlands were retrospectively included in this study. These trauma centres had different standardised protocols for acute infection after osteosynthesis: 39 patients were selected from protocol A and 32 from protocol B. Both protocols involve immediate surgical debridement and soft tissue coverage, but differ in antibiotic approach: (A) immediate empirical combination antibiotic therapy with rifampicin, or (B) postponed (1–5Β days) targeted antibiotic therapy. The primary outcome of these protocols was success, defined as a fracture healing in the absence of infection. The secondary outcome was antibiotic resistance patterns. Logistic regression was conducted on patients and treatment-related factors in association with primary success. Results: Primary success was achieved in 72% of protocol A patients, in 47% of those in protocol B (P = 0.033), and with prolongation of treatment success was achieved in 90% and 78% of patients, respectively. Protocol A exhibited a better primary success rate (adjusted OR 3.45, CI 1.13–10.52) when adjusted for age and soft tissue injury. There was no significant difference in antibiotic resistance between the two protocols. Conclusion: Both protocols yielded high overall success rates. Immediate empirical antibiotics can be used safely without additional bacterial resistance and may contribute to increased success rates
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