24 research outputs found
Après une décennie de « buzz » : quelle pertinence pour le concept de modèle d’affaires en stratégie?
Une dizaine d’annĂ©es après la renaissance manifeste de l’intĂ©rĂŞt des praticiens, puis des chercheurs, pour le concept de modèle d’affaires (business model), la question de sa pertinence au regard des concepts et des outils existants en stratĂ©gie persiste. Concept polysĂ©mique? Concept « valise »? Concept utile? Concept durable? Autant de questions qui, au-delĂ de la popularitĂ© du concept, nous invitent Ă porter un regard Ă la fois critique et constructif sur le modèle d’affaires dans le champ du management stratĂ©gique.Alors que notre pratique d’enseignement de la stratĂ©gie et d’accompagnement de projets d’innovation nous amenait Ă questionner la pertinence du concept/outil du modèle d’affaires, il nous sembla qu’un tour de table s’imposait pour tenter de rĂ©pondre aux questions soulevĂ©es. Ce tour de table s’est tenu le 8 juin 2011 lors de la XXe confĂ©rence de l’Association Internationale de Management StratĂ©gique (AIMS) Ă Nantes. Ce petit ouvrage a pour but de faire partager au lecteur l’intĂ©gralitĂ© des propos Ă©changĂ©s ce jour-lĂ
Feeding mice with diets containing mercury-contaminated fish flesh from French Guiana: a model for the mercurial intoxication of the Wayana Amerindians
International audienc
Proposal of classification of mercury and its compounds for reprotoxicity
Environmental Epidemiology And Exposure.Joint International Conference of the International Society of Exposure Analysis (ISEA) and the International Society for Environmental Epidemiology (ISEE)info:eu-repo/semantics/nonPublishe
Economic evaluation of health consequences of prenatal methylmercury exposure in France
<p>Abstract</p> <p>Background</p> <p>Evidence of a dose–response relationship between prenatal exposure to methylmercury (MeHg) and neurodevelopmental consequences in terms of IQ reduction, makes it possible to evaluate the economic consequences of MeHg exposures.</p> <p>Objective</p> <p>To perform an economic evaluation of annual national benefits of reduction of the prenatal MeHg exposure in France.</p> <p>Methods</p> <p>We used data on hair-Hg concentrations in French women of childbearing age (18–45 years) from a national sample of 126 women and from two studies conducted in coastal regions (n = 161and n = 503). A linear dose response function with a slope of 0.465 IQ point reduction per μg/g increase in hair-Hg concentration was used, along with a log transformation of the exposure scale, where a doubling of exposure was associated with a loss of 1.5 IQ points. The costs calculations utilized an updated estimate of €<sub>2008</sub> 17,363 per IQ point decrement, with three hypothetical exposure cut-off points (hair-Hg of 0.58, 1.0, and 2.5 μg/g).</p> <p>Results</p> <p>Because of higher exposure levels of women in coastal communities, the annual economic impacts based on these data were greater than those using the national data, i.e. € 1.62 billion (national), and € 3.02 billion and € 2.51 billion (regional), respectively, with the linear model, and € 5.46 billion (national), and € 9.13 billion and € 8.17 billion (regional), with the log model, for exposures above 0.58 μg/g.</p> <p>Conclusions</p> <p>These results emphasize that efforts to reduce MeHg exposures would have high social benefits by preventing the serious and lifelong consequences of neurodevelopmental deficits in children.</p