581 research outputs found

    Multiscale Mass-Spring Models of Carbon Nanotube Arrays Accounting for Mullins-like Behavior and Permanent Deformation

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    Based on a one-dimensional discrete system of bistable springs, a mechanical model is introduced to describe plasticity and damage in carbon nanotube (CNT) arrays. The energetics of the mechanical system are investigated analytically, the stress-strain law is derived, and the mechanical dissipation is computed, both for the discrete case as well as for the continuum limit. An information-passing approach is developed that permits the investigation of macroscopic portions of the material. As an application, the simulation of a cyclic compression experiment on real CNT foam is performed, considering both the material response during the primary loading path from the virgin state and the damaged response after preconditioning

    Continuum limits of bistable spring models of carbon nanotube arrays accounting for material damage

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    Using chains of bistable springs, a model is derived to investigate the plastic behavior of carbon nanotube arrays with damage. We study the preconditioning effect due to the loading history by computing analytically the stress-strain pattern corresponding to a fatigue-type damage of the structure. We identify the convergence of the discrete response to the limiting case of infinitely many springs, both analytically in the framework of Gamma-convergence, as well as numerically.Comment: 11 pages, 1 figur

    Volume 14. Article 1. The striped bass, Roccus saxatilis.

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    https://elischolar.library.yale.edu/bulletin_yale_bingham_oceanographic_collection/1151/thumbnail.jp

    Interactions of ingested food, beverage, and tobacco components involving human cytochrome P4501A2, 2A6, 2E1, and 3A4 enzymes.

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    Human cytochrome P450 (P450) enzymes are involved in the oxidation of natural products found in foods, beverages, and tobacco products and their catalytic activities can also be modulated by components of the materials. The microsomal activation of aflatoxin B1 to the exo-8,9-epoxide is stimulated by flavone and 7,8-benzoflavone, and attenuated by the flavonoid naringenin, a major component of grapefruit. P4502E1 has been demonstrated to play a potentially major role in the activation of a number of very low-molecular weight cancer suspects, including ethyl carbamate (urethan), which is present in alcoholic beverages and particularly stone brandies. The enzyme (P4502E1) is also known to be inducible by ethanol. Tobacco contains a large number of potential carcinogens. In human liver microsomes a significant role for P4501A2 can be demonstrated in the activation of cigarette smoke condensate. Some of the genotoxicity may be due to arylamines. P4501A2 is also inhibited by components of crude cigarette smoke condensate. The tobacco-specific nitrosamines are activated by a number of P450 enzymes. Of those known to be present in human liver, P4501A2, 2A6, and 2E1 can activate these nitrosamines to genotoxic products

    Vaginal metastasis of a Ewing sarcoma five years after resection of the primary tumor

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    A 35-year-old female presented with pain and swelling of the distal left radius. A diagnosis of Ewing sarcoma was made and she underwent neoadjuvant chemotherapy and surgery. Macroscopic viable areas remained on the map of the surgical specimen; as such, she was classified as a poor responder and received high dose adjuvant chemotherapy. She remained disease-free for five years, until age 40. A vaginal polyp was then detected during a routine gynaecologic examination. It was removed and histopathology revealed metastatic Ewing sarcoma
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