MODELLING ELASTICITY OF INJECTION MOULDED SHORT FIBRE REINFORCED POLYMERS: COMPARISON BETWEEN EXPERIMENTAL AND ANALYTICAL APPROACHES

In this work we analysed a sample of short fibre reinforced polyamide extracted from an injection moulded plate. We derived local values of the elastic constants by two different numerical methods, one based on simulation and one based on the reconstruction of the sample's microstructure by micro - CT. Results were compared in terms of moduli of elasticity, assuming an orthotropic material model. Fibre orientation was first simulated by process simulation and results were checked against experimental data obtained by the optical section method. Then, fibre orientation data were used for micro-mechanical modelling of the elastic behaviour by means of mean field homogenisation tools. The experimentally based approach was based on micro computed tomography reconstructions of the inner structure of samples extracted from the injection moulded plate. Using numerical models based on the Cell Method, the elastic behaviour of the reconstructed volume was simulated and results were compared with analytical models based on process simulations and homogenization

Chandra Observations of 3C Radio Sources with z<0.3: Nuclei, Diffuse Emission, Jets and Hotspots

We report on our Chandra Cycle 9 program to observe half of the 60 (unobserved by Chandra) 3C radio sources at z<0.3 for 8 ksec each. Here we give the basic data: the X-ray intensity of the nuclei and any features associated with radio structures such as hot spots and knots in jets. We have measured fluxes in soft, medium and hard bands and are thus able to isolate sources with significant intrinsic column density. For the stronger nuclei, we have applied the standard spectral analysis which provides the best fit values of X-ray spectral index and column density. We find evidence for intrinsic absorption exceeding a column density of 10^{22} cm^{-2} for one third of our sources.Comment: 12 pages, 37 figures (the complete version of the paper with all figures is available on line, see appendix for details), ApJ accepte

Testing Black Hole Jet Scaling Relations in Low Luminosity AGN

We present the results of the analysis of a sample of 17 low-luminosity (L_x < 1e42 erg/s), radio loud AGNs in massive galaxies. The sample is extracted from the SDSS database and it spans uniformly a wide range in optical [OIII] emission line and radio luminosity, but within a narrow redshift range (0.05 < z < 0.11) and a narrow super massive black hole mass range (~ 1e8 M_sun). For these sources we measured core X-ray emission with the Chandra X-ray telescope and radio emission with the VLA. Our main goal is to establish which emission component, if any, can be regarded as the most reliable accretion/jet-power estimator at these regimes. In order to do so, we studied the correlation between emission line properties, radio luminosity, radio spectral slopes and X-ray luminosity, as well as more complex multi-variate relations involving black hole mass, such as the fundamental plane of black hole activity. We find that 15 out of 17 sources of our sample can be classified as Low-Excitation Galaxies (LEG) and their observed properties suggest X-ray and radio emission to originate from the jet basis. We also find that X-ray emission does not appear to be affected by nuclear obscuration and can be used as a reliable jet-power estimator. More generally, X-ray, radio and optical emission appear to be related, although no tight correlation is found. In accordance with a number of recent studies of this class of objects these findings may be explained by a lack of cold (molecular) gaseous structures in the innermost region of these massive galaxies.Comment: 11 pages, 6 figures, published in MNRA

Band alignment and interlayer hybridisation in transition metal dichalcogenide/hexagonal boron nitride heterostructures

In van der Waals heterostructures, the relative alignment of bands between layers, and the resulting band hybridisation, are key factors in determining a range of electronic properties. This work examines these effects for heterostructures of transition metal dichalcogenides (TMDs) and hexagonal boron nitride (hBN), an ubiquitous combination given the role of hBN as an encapsulating material. By comparing results of density functional calculations with experimental angle-resolved photoemission spectroscopy (ARPES) results, we explore the hybridisation between the valence states of the TMD and hBN layers, and show that it introduces avoided crossings between the TMD and hBN bands, with umklapp processes opening `ghost' avoided crossings in individual bands. Comparison between DFT and ARPES spectra for the MoSe$_2$/hBN heterostructure shows that the valence bands of MoSe$_2$ and hBN are significantly further separated in energy in experiment as compared to DFT. We then show that a novel scissor operator can be applied to the hBN valence states in the DFT calculations, to correct the band alignment and enable quantitative comparison to ARPES, explaining avoided crossings and other features of band visibility in the ARPES spectra

Determinants of adults' intention to vaccinate against pandemic swine flu

This article has been made available through the Brunel Open Access Publishing Fund.This article has been made available through the Brunel Open Access Publishing Fund.Background: Vaccination is one of the cornerstones of controlling an influenza pandemic. To optimise vaccination rates in the general population, ways of identifying determinants that influence decisions to have or not to have a vaccination need to be understood. Therefore, this study aimed to predict intention to have a swine influenza vaccination in an adult population in the UK. An extension of the Theory of Planned Behaviour provided the theoretical framework for the study. Methods: Three hundred and sixty two adults from the UK, who were not in vaccination priority groups, completed either an online (n = 306) or pen and paper (n = 56) questionnaire. Data were collected from 30th October 2009, just after swine flu vaccination became available in the UK, and concluded on 31st December 2009. The main outcome of interest was future swine flu vaccination intentions. Results: The extended Theory of Planned Behaviour predicted 60% of adults’ intention to have a swine flu vaccination with attitude, subjective norm, perceived control, anticipating feelings of regret (the impact of missing a vaccination opportunity), intention to have a seasonal vaccine this year, one perceived barrier: “I cannot be bothered to get a swine flu vaccination” and two perceived benefits: “vaccination decreases my chance of getting swine flu or its complications” and “if I get vaccinated for swine flu, I will decrease the frequency of having to consult my doctor,” being significant predictors of intention. Black British were less likely to intend to have a vaccination compared to Asian or White respondents. Conclusions: Theoretical frameworks which identify determinants that influence decisions to have a pandemic influenza vaccination are useful. The implications of this research are discussed with a view to maximising any future pandemic influenza vaccination uptake using theoretically-driven applications.This article is available through the Brunel Open Access Publishing Fund

Chlorpromazine for schizophrenia: a Cochrane systematic review of 50 years of randomised controlled trials

BACKGROUND: Chlorpromazine (CPZ) remains one of the most common drugs used for people with schizophrenia worldwide, and a benchmark against which other treatments can be evaluated. Quantitative reviews are rare; this one evaluates the effects of chlorpromazine in the treatment of schizophrenia in comparison with placebo. METHODS: We sought all relevant randomised controlled trials (RCT) comparing chlorpromazine to placebo by electronic and reference searching, and by contacting trial authors and the pharmaceutical industry. Data were extracted from selected trials and, where possible, synthesised and random effects relative risk (RR), the number needed to treat (NNT) and their 95% confidence intervals (CI) calculated. RESULTS: Fifty RCTs from 1955–2000 were included with 5276 people randomised to CPZ or placebo. They constitute 2008 person-years spent in trials. Meta-analysis of these trials showed that chlorpromazine promotes a global improvement (n = 1121, 13 RCTs, RR 0.76 CI 0.7 to 0.9, NNT 7 CI 5 to 10), although a considerable placebo response is also seen. People allocated to chlorpromazine tended not to leave trials early in both the short (n = 945, 16 RCTs, RR 0.74 CI 0.5 to 1.1) and medium term (n = 1861, 25 RCTs, RR 0.79 CI 0.6 to 1.1). There were, however, many adverse effects. Chlorpromazine is sedating (n = 1242, 18 RCTs, RR 2.3 CI 1.7 to 3.1, NNH 6 CI 5 to 8), increases a person's chances of experiencing acute movement disorders, Parkinsonism and causes low blood pressure with dizziness and dry mouth. CONCLUSION: It is understandable why the World Health Organization (WHO) have endorsed and included chlorpromazine in their list of essential drugs for use in schizophrenia. Low- and middle-income countries may have more complete evidence upon which to base their practice compared with richer nations using recent innovations

The 1.6 micron near infrared nuclei of 3C radio galaxies: Jets, thermal emission or scattered light?

Using HST NICMOS 2 observations we have measured 1.6-micron near infrared nuclear luminosities of 100 3CR radio galaxies with z<0.3, by modeling and subtracting the extended emission from the host galaxy. We performed a multi-wavelength statistical analysis (including optical and radio data) of the properties of the nuclei following classification of the objects into FRI and FRII, and LIG (low-ionization galaxies), HIG (high-ionization galaxies) and BLO (broad-lined objects) using the radio morphology and optical spectra, respectively. The correlations among near infrared, optical, and radio nuclear luminosity support the idea that the near infrared nuclear emission of FRIs has a non-thermal origin. Despite the difference in radio morphology, the multi-wavelength properties of FRII LIG nuclei are statistically indistinguishable from those of FRIs, an indication of a common structure of the central engine. All BLOs show an unresolved near infrared nucleus and a large near infrared excess with respect to FRII LIGs and FRIs of equal radio core luminosity. This requires the presence of an additional (and dominant) component other than the non-thermal light. Considering the shape of their spectral energy distribution, we ascribe the origin of their near infrared light to hot circumnuclear dust. A near infrared excess is also found in HIGs, but their nuclei are substantially fainter than those of BLO. This result indicates that substantial obscuration along the line-of-sight to the nuclei is still present at 1.6 micron. Nonetheless, HIGs nuclei cannot simply be explained in terms of dust obscuration: a significant contribution from light reflected in a circumnuclear scattering region is needed to account for their multiwavelength properties.Comment: 20 pages, 16 figures. Accepted for publication on Ap

Solvent Effects on Electronic Excitations of an Organic Chromophore.

In this work we study the solvatochromic shift of a selected low-energy excited state of alizarin in water by using a linear-scaling implementation of large-scale time-dependent density functional theory (TDDFT). While alizarin, a small organic dye, is chosen as a simple example of solute-solvent interactions, the findings presented here have wider ramifications for the realistic modeling of dyes, paints, and pigment-protein complexes. We find that about 380 molecules of explicit water need to be considered in order to yield an accurate representation of the solute-solvent interaction and a reliable solvatochromic shift. By using a novel method of constraining the TDDFT excitation vector, we confirm that the origin of the slow convergence of the solvatochromic shift with system size is due to two different effects. The first factor is a strong redshift of the excitation due to an explicit delocalization of a small fraction of the electron and the hole from the alizarin onto the water, which is mainly confined to within a distance of 7 Å from the alizarin molecule. The second factor can be identified as long-range electrostatic influences of water molecules beyond the 7 Å region on the ground-state properties of alizarin. We also show that these electrostatic influences are not well reproduced by a QM/MM model, suggesting that full QM studies of relatively large systems may be necessary in order to obtain reliable results.TJZ acknowledges the support of EPSRC Grant EP/J017639/1 and funding under the embedded CSE programme of the ARCHER UK National Supercomputing Service. MCP and PDH acknowledge the support of EPSRC grant EP/J015059/1.This is the final version of the article. It first appeared from the American Chemical Society via https://doi.org/10.1021/acs.jctc.5b0101

Gas Accretion and Giant Lyman-alpha Nebulae

Several decades of observations and discoveries have shown that high-redshift AGN and massive galaxies are often surrounded by giant Lyman-alpha nebulae extending in some cases up to 500 kpc in size. In this review, I discuss the properties of the such nebulae discovered at z>2 and their connection with gas flows in and around the galaxies and their halos. In particular, I show how current observations are used to constrain the physical properties and origin of the emitting gas in terms of the Lyman-alpha photon production processes and kinematical signatures. These studies suggest that recombination radiation is the most viable scenario to explain the observed Lyman-alpha luminosities and Surface Brightness for the large majority of the nebulae and imply that a significant amount of dense, ionized and cold clumps should be present within and around the halos of massive galaxies. Spectroscopic studies suggest that, among the giant Lyman-alpha nebulae, the one associated with radio-loud AGN should have kinematics dominated by strong, ionized outflows within at least the inner 30-50 kpc. Radio-quiet nebulae instead present more quiescent kinematics compatible with stationary situation and, in some cases, suggestive of rotating structures. However, definitive evidences for accretion onto galaxies of the gas associated with the giant Lyman-alpha emission are not unambiguously detected yet. Deep surveys currently ongoing using other bright, non-resonant lines such as Hydrogen H-alpha and HeII1640 will be crucial to search for clearer signatures of cosmological gas accretion onto galaxies and AGN.Comment: Invited review to appear in Gas Accretion onto Galaxies, Astrophysics and Space Science Library, eds. A. J. Fox & R. Dave', to be published by Springe

Residual stresses and practical adhesion: effect of organo-metallic complex formation and crystallization

Epoxy-amine liquid pre-polymers are often applied onto metallic substrates and cured to obtain painted materials or bonded joint structures. The overall performance of such systems depends on the interphase created between the epoxy amine polymer and the metallic substrate. When epoxyamine liquid mixtures are applied onto a metallic oxide layer, concomitant amine chemisorption and oxide dissolution occur leading to organo-metallic complex formation. Depending on the amine nature, as soon as the organo-metallic complex concentration is higher than the solubility product (e.g., isophoronediamine (IPDA)), these organo-metallic complexes crystallize as sharp needles. At the same time, the uncrystallized organo-metallic complexes react with the epoxy monomer to form, after curing cycle, a new network. Moreover, the crystal size increases with the solid/liquid contact time leading to an increase of intrinsic residual stresses and Young's modulus. When aliphatic diethylenetriamine (DETA) was used, no crystallization occurred, but the interphase formation was observed. The aim of this study was to understand and to establish the role of crystallization of organo-metallic complexes formed within the interphase on the practical adhesion performance. As the crystallization of the organo-metallic complex depends on the nature of the amine, two amine hardeners were used (IPDA inducing the formation of crystals and DETA without formation of crystals). For DGEBA-IPDA systems, the ultimate load decreases while residual stresses increase when the liquid/solid contact time increases. When no crystal formation was observed (e.g., DGEBADETA system), residual stresses, coating Young's modulus and ultimate load values all remained nearly constant irrespective of the liquid/solid contact time