342 research outputs found
CHARACTERIZATION OF NEMOTIC DENTAL FIBROBLASTS
Oral Communication presented at the ";Forum des Jeunes Chercheurs";, Brest (France) 2011
Effect of the Photon's Brownian Doppler Shift on the Weak-Localization Coherent-Backscattering Cone
We report the first observation of the dependence of the
coherent-backscattering (CBS) enhanced cone with the frequency of the
backscattered photon. The experiment is performed on a diffusing liquid
suspension and the Doppler broadening of light is induced by the Brownian
motion of the scatterers. Heterodyne detection on a CCD camera is used to
measure the complex field (i.e., the hologram) of the light that is
backscattered at a given frequency. The analysis of the holograms yield the
frequency and the propagation direction of the backscattered photons. We
observe that the angular CBS cone becomes more narrow in the tail of the
Brownian spectrum. The experimental results are in good agreement with a simple
theoretical model
Theoretical study of Acousto-optical coherence tomography using random phase jumps on US and light
Acousto-Optical Coherence Tomography (AOCT) is variant of Acousto Optic
Imaging (called also ultrasonic modulation imaging) that makes possible to get
z resolution with acoustic and optic Continuous Wave (CW) beams. We describe
here theoretically the AOCT e ect, and we show that the Acousto Optic tagged
photons remains coherent if they are generated within a speci c z region of the
sample. We quantify the z selectivity for both the tagged photon eld, and for
the M. Lesa re et al. photorefractive signal
Comparison of the properties of two fossil groups of galaxies with the normal group NGC 6034 based on multiband imaging and optical spectroscopy
We collected multiband imaging and spectroscopy for two fossil groups (RX
J1119.7+2126 and 1RXS J235814.4+150524) and one normal group (NGC 6034). We
computed photometric redshifts in the central zones of each group, combining
previous data with the SDSS five-band data. For each group we investigated the
red sequence (RS) of the color-magnitude relation and computed the luminosity
functions, stellar population ages and distributions of the group members.
Spectroscopy allowed us to investigate the large-scale surroundings of these
groups and the substructure levels in 1RXS J235814.4+150524 and NGC 6034. The
large-scale environment of 1RXS J235814.4+150524 is poor, though its galaxy
density map shows a clear signature of the surrounding cosmic web. RX
J1119.7+2126 appears to be very isolated, while the cosmic environment of NGC
6034 is very rich. At the group scale, 1RXS J235814.4+150524 shows no
substructure. Galaxies with recent stellar populations seem preferentially
located in the group outskirts. A RS is discernable for all three groups in a
color-magnitude diagram. The luminosity functions based on photometric redshift
selection and on statistical background subtraction have comparable shapes, and
agree with the few points obtained from spectroscopic redshifts. These
luminosity functions show the expected dip between first and second brightest
galaxies for the fossil groups only. Their shape is also regular and relatively
flat at faint magnitudes down to the completeness level for RX J1119.7+2126 and
NGC 6034, while there is a clear lack of faint galaxies for 1RXS
J235814.4+150524. RX J1119.7+2126 is definitely classified as a fossil group;
1RXS J235814.4+150524 also has properties very close to those of a fossil
group, while we confirm that NGC 6034 is a normal group.Comment: Accepted in A&A, english-improved, 5 jpeg figures, and shortened
abstrac
Dark-field digital holographic microscopy for 3D-tracking of gold nanoparticles
We present a new technique that combines off-axis Digital Holography and Dark
Field Microscopy to track 100nm gold particles diffusing in water. We show that
a single hologram is sufficient to localize several particles in a thick sample
with a localization accuracy independent of the particle position. From our
measurements we reconstruct the trajectories of the particles and derive their
3D diffusion coefficient. Our results pave the way for quantitative studies of
the motion of single nanoparticle in complex media
A human leukocyte antigen imputation study uncovers possible genetic interplay between gut inflammatory processes and autism spectrum disorders
Autism spectrum disorders (ASD) are neurodevelopmental conditions that are for subsets of individuals, underpinned by dysregulated immune processes, including inflammation, autoimmunity, and dysbiosis. Consequently, the major histocompatibility complex (MHC)-hosted human leukocyte antigen (HLA) has been implicated in ASD risk, although seldom investigated. By utilizing a GWAS performed by the EU-AIMS consortium (LEAP cohort), we compared HLA and MHC genetic variants, single nucleotide polymorphisms (SNP), and haplotypes in ASD individuals, versus typically developing controls. We uncovered six SNPs, namely rs9268528, rs9268542, rs9268556, rs14004, rs9268557, and rs8084 that crossed the Bonferroni threshold, which form the underpinnings of 3 independent genetic pathways/blocks that differentially associate with ASD. Block 1 (rs9268528-G, rs9268542-G, rs9268556-C, and rs14004-A) afforded protection against ASD development, whilst the two remaining blocks, namely rs9268557-T, and rs8084-A, associated with heightened risk. rs8084 and rs14004 mapped to the HLA‐DRA gene, whilst the four other SNPs located in the BTNL2 locus. Different combinations amongst BTNL2 SNPs and HLA amino acid variants or classical alleles were found either to afford protection from or contribute to ASD risk, indicating a genetic interplay between BTNL2 and HLA. Interestingly, the detected variants had transcriptional and/or quantitative traits loci implications. As BTNL2 modulates gastrointestinal homeostasis and the identified HLA alleles regulate the gastrointestinal tract in celiac disease, it is proposed that the data on ASD risk may be linked to genetically regulated gut inflammatory processes. These findings might have implications for the prevention and treatment of ASD, via the targeting of gut-related processes
Critical Indices as Limits of Control Functions
A variant of self-similar approximation theory is suggested, permitting an
easy and accurate summation of divergent series consisting of only a few terms.
The method is based on a power-law algebraic transformation, whose powers play
the role of control functions governing the fastest convergence of the
renormalized series. A striking relation between the theory of critical
phenomena and optimal control theory is discovered: The critical indices are
found to be directly related to limits of control functions at critical points.
The method is applied to calculating the critical indices for several difficult
problems. The results are in very good agreement with accurate numerical data.Comment: 1 file, 5 pages, RevTe
Gene expression profiling reveals a conserved microglia signature in larval zebrafish
Microglia are the resident macrophages of the brain. Over the past decade, our understanding of the function of these cells has significantly improved. Microglia do not only play important roles in the healthy brain but are involved in almost every brain pathology. Gene expression profiling allowed to distinguish microglia from other macrophages and revealed that the full microglia signature can only be observed in vivo. Thus, animal models are irreplaceable to understand the function of these cells. One of the popular models to study microglia is the zebrafish larva. Due to their optical transparency and genetic accessibility, zebrafish larvae have been employed to understand a variety of microglia functions in the living brain. Here, we performed RNA sequencing of larval zebrafish microglia at different developmental time points: 3, 5, and 7 days post fertilization (dpf). Our analysis reveals that larval zebrafish microglia rapidly acquire the core microglia signature and many typical microglia genes are expressed from 3 dpf onwards. The majority of changes in gene expression happened between 3 and 5 dpf, suggesting that differentiation mainly takes place during these days. Furthermore, we compared the larval microglia transcriptome to published data sets of adult zebrafish microglia, mouse microglia, and human microglia. Larval microglia shared a significant number of expressed genes with their adul
The XXL Survey IV. Mass-temperature relation of the bright cluster sample
The XXL survey is the largest survey carried out by XMM-Newton. Covering an area of 50deg, the survey contains galaxy clusters out to a redshift 2 and to an X-ray flux limit of . This paper is part of the first release of XXL results focussed on the bright cluster sample. We investigate the scaling relation between weak-lensing mass and X-ray temperature for the brightest clusters in XXL. The scaling relation is used to estimate the mass of all 100 clusters in XXL-100-GC. Based on a subsample of 38 objects that lie within the intersection of the northern XXL field and the publicly available CFHTLenS catalog, we derive the of each system with careful considerations of the systematics. The clusters lie at and span a range of . We combine our sample with 58 clusters from the literature, increasing the range out to 10keV. To date, this is the largest sample of clusters with measurements that has been used to study the mass-temperature relation. The fit () to the XXL clusters returns a slope and intrinsic scatter ; the scatter is dominated by disturbed clusters. The fit to the combined sample of 96 clusters is in tension with self-similarity, and . Overall our results demonstrate the feasibility of ground-based weak-lensing scaling relation studies down to cool systems of temperature and highlight that the current data and samples are a limit to our statistical precision. As such we are unable to determine whether the validity of hydrostatic equilibrium is a function of halo mass. An enlarged sample of cool systems, deeper weak-lensing data, and robust modelling of the selection function will help to explore these issues further
- …