1,488 research outputs found
Defending Judge Roy Moore: a case study of persuasion resistance strategies.
This study explored what kind of persuasive resistance strategies people used when faced with information that was contrary to their existing belief system. A typology of resistance strategies as articulated by Fransen, Smit, & Verlegh (2015), was used to guide the development of a coding system. I coded the public quotes of supporters of a political candidate after sexual misconduct allegations came to light. The first research question investigated was: What kinds of persuasion resistance strategies were Roy Moore supporters most likely to use? The second was: What kinds of persuasion resistance strategies used tended to co-occur? The most important result of this exploratory study was showing that not only do people think about the resistance strategies they are going to use, but they also verbalize them. People mentally process contesting information, then give them a voice. Empowering strategies emerged as a particularly important persuasion resistance strategy in the current study. A larger study could try to find ways to encourage people to explore the facts of a given situation by anticipating (probability) the resistance responses and dealing with them in naturally occurring contexts
Statistical mapping of sheet aiquile SE-20-9 (national map) making use of ERTS images
New possibilities of remote sensing by means of satellites to do research on natural resources are reported. These images make it possible to carry out integrated studies of natural resources in the shortest time possible and with small investments. Various maps and a complete description of each are included. With the use of these satellites, scientists can hopefully plan development projects at the national level
Viability of Neurospora conidia from stock cultures on silica gel
Viability of Neurospora conidia from stock cultures on silica ge
Further information on the origin of the Yale and Oak Ridge wild-type strains of Neurospora crassa
Further information on the origin of the Yale and Oak Ridge wild-type strains of Neurospora crass
Dual HLA B*42 and B*81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants
Closely related HLA alleles presenting similar HIV-1 epitopes can be associated with variable clinical outcome. Here the authors report their findings on CD8+ T cell responses to the HIV-1 Gag-p24 TL9 immunodominant epitope in the context of closely related protective and less protective HLA alleles, and their differential effect on viral contro
HLA-Associated viral mutations are common in human immunodeficiency virus type 1 elite controllers
Elite controllers (EC) of human immunodeficiency virus type 1 (HTV-1) maintain viremia below the limit of detection without antiretroviral treatment. Virus-specific cytotoxic CD8+ T lymphocytes are believed to play a crucial role in viral containment, but the degree of immune imprinting and compensatory mutations in EC is unclear. We obtained plasma gag, pol, and nef sequences from HLA-diverse subjects and found that 30 to 40% of the predefined HLA-associated polymorphic sites show evidence of immune selection pressure in EC., compared to approximately 50% of the sites in chronic progressors. These data indicate ongoing viral replication and escape from cytotoxic T lymphocytes are present even in strictly controlled HTV-1 infection
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Enhanced bioremediation of subsurface contamination: Enzyme recruitment and redesign
Subsurface systems containing radionuclide, heavy metal, and organic wastes must be carefully attended to avoid further impacts to the environment or exposures to human populations. It is appropriate, therefore, to invest in basic research to develop the requisite tools and methods for addressing complex cleanup problems. The rational modification of subsurface microoganisms by enzyme recruitment and enzyme design, in concert with engineered systems for delivery of microorganisms and nutrients to the contaminated zone, are potentially useful tools in the spectrum of approaches that will be required for successful remediation of deep subsurface contamination
Discrimination as a frame-of-reference effect in overlapping friendship communities of ethnically diverse youth
Objectives: To what extent is the frame of reference of overlapping friendship communities important for young people’s feelings of discrimination and subjective wellbeing? That is, do youth feel better or worse to the extent that they feel less or more discrimination than their friends? Methods: Participants (N=898; Mage=14.13; SDage=3.37; 46% females; 46% Whites; 20% Indigenous; 34% other minorities) were high school students of three ethnically diverse, low SES public schools in New South Wales, Australia. Cross-sectional data were collected to measure felt discrimination, mental health, subjective wellbeing, social support and nominations of close friends. A state-of-the-art method of clustering links was used to identify overlapping friendship communities, and multiple membership multilevel models were run to examine whether community level discrimination moderated the link between individual level discrimination and wellbeing. Results: When the community level discrimination was low, there was no wellbeing related cost or benefit of individual level discrimination. But when the community level discrimination was high, individuals in those communities who themselves felt low discrimination had better wellbeing than individuals who themselves felt high discrimination. Conclusions: We provide evidence for a frame-ofreference effect involving discrimination. Individuals’ relative standing in their friendship communities with high group-level discrimination reliably predicted the individuals’ wellbeing levels, regardless of ethnicity. The results highlight the importance of identifying overlapping friendship communities for understanding the dynamics of discrimination and wellbeing of ethnically diverse youth
Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals
P09-11. Reduced replication capacity of NL4-3 chimeric viruses encoding RT-Integrase sequences from HIV-1 elite controllers
Background: Spontaneous control of HIV to 0.05). Viruses derived from HLA-B57+ EC (N = 20) appeared to replicate slower than those from B57+ progressors (N = 8) (p = 0.004). Similar results were observed between B51+ EC (N = 4) and B51+ progressors (N = 10) (p = 0.024), but not between B27+ EC (N = 9) and B27+ progressors (N = 5) (p = 0.437). Conclusion: This study extends previous observations for Gag and demonstrates that Pol variants from EC also display reduced function. The association between fitness and expression of certain HLA that present Pol epitopes suggests that immune-mediated mutations impairing viral fitness may play a key role in spontaneous control of HIV. Results indicate that HLA alleles responsible for such defects in protein function may differ among viral genes. Further identification of HLA-associated changes in HIV may allow design of vaccines targeting the most vulnerable regions of the virus
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