Total Reflection and Negative Refraction of Dipole-Exchange Spin Waves at Magnetic Interfaces: Micromagnetic Modeling Study

We demonstrated that dipole-exchange spin waves traveling in geometrically restricted magnetic thin films satisfy the same laws of reflection and refraction as light waves. Moreover, we found for the first time novel wave behaviors of dipole-exchange spin waves such as total reflection and negative refraction. The total reflection in laterally inhomogeneous thin films composed of two different magnetic materials is associated with the forbidden modes of refracted dipole-exchange spin waves. The negative refraction occurs at a 90 degree domain-wall magnetic interface that is introduced by a cubic magnetic anisotropy in the media, through the anisotropic dispersion of dipole-exchange spin waves.Comment: 13 pages, 5 figure

Electric-current-driven vortex-core reversal in soft magnetic nanodots

The authors report on electric-current-driven vortex-core (VC) reversal (switching) and the accompanying spin-wave emission, driven by spin-polarized ac currents of different amplitudes and frequencies, investigated by micromagnetic calculations of the dynamic evolution of a magnetic vortex in Permalloy nanodots. The magnetization orientation of the VC is effectively switchable between its upward and downward bistates and controllable by applying current above its threshold density, but with sufficiently small magnitude at frequencies close to the vortex eigenfrequency. This VC reversal phenomenon occurs through the creation of a vortex-antivortex pair and the subsequent annihilation of the initial vortex and the created antivortex, when the velocity of the initial VC reaches its critical value of approximately 340 +/- 20 m/s for the given material and geometry. In the course of these serial processes and immediately after VC switching, strong spin waves are emitted. These results provide physical insights into how and when current-driven VC switching takes place, thereby offering a means to manipulate bistate VC orientations.open554

Oppositely rotating eigenmodes of spin-polarized current-driven vortex gyrotropic motions in elliptical nanodots

The authors found that there exist two different rotational eigenmodes of oppositely rotating sense in spin-polarized current-driven vortex gyrotropic motions in soft magnetic elliptical nanodots. Simple mathematical expressions were analytically calculated by adopting vortex-core (VC)-rotation-sense- dependent dynamic susceptibility tensors based on the linearized Thiele equation [Phys. Rev. Lett. 30, 230 (1973)]. The numerical calculations of those analytical expressions were confirmed by micromagnetic simulations, revealing that linear-regime steady-state VC motions driven by any polarized oscillating currents can be interpreted simply by the superposition of the clockwise and counterclockwise rotational eigenmodes. The shape of the orbital trajectories of the two eigenmodes is determined only by the lateral dimension of elliptical dots. Additionally, the orbital radii and phases of the two eigenmodes' VC motions were found to markedly vary with the frequency of applied currents, particularly across the vortex eigenfrequency and according to the vortex polarization, which results in overall VC motions driven by any polarized oscillating currents.open8

Data of methylome and transcriptome derived from human dilated cardiomyopathy

AbstractAlterations in DNA methylation and gene expression have been implicated in the development of human dilated cardiomyopathy (DCM). Differentially methylated probes (DMPs) and differentially expressed genes (DEGs) were identified between the left ventricle (LV, a pathological locus for DCM) and the right ventricle (RV, a proxy for normal hearts). The data in this DiB are for supporting our report entitled “Methylome analysis reveals alterations in DNA methylation in the regulatory regions of left ventricle development genes in human dilated cardiomyopathy” (Bong-Seok Jo, In-Uk Koh, Jae-Bum Bae, Ho-Yeong Yu, Eun-Seok Jeon, Hae-Young Lee, Jae-Joong Kim, Murim Choi, Sun Shim Choi, 2016) [1]

Prognostic Implication of Longitudinal Changes of Left Ventricular Global Strain After Chemotherapy in Cardiac Light Chain Amyloidosis

AimCardiac involvement is the main prognostic determinant in AL amyloidosis. We sought to determine the prognostic significance of longitudinal change of left ventricular (LV) global longitudinal strain (GLS) in cardiac light chain (AL) amyloidosis patients undergoing chemotherapy.Methods and ResultWe retrospectively investigated 117 cardiac AL amyloidosis patients who underwent chemotherapy from 2005 to 2019. All patients underwent comprehensive 2D conventional transthoracic echocardiography at baseline and after completion of first-line chemotherapy. Speckle tracking analysis of images was performed offline. Absolute value of LV GLS was expressed as [LV GLS] and change of [LV GLS] after chemotherapy was expressed as Δ [LV GLS]. Clinical outcomes including cardiac response and all-cause mortality were analyzed.Baseline clinical and echocardiographic parameters were similar in patients with and without CR. Δ [LV GLS] significantly differed between the CR and non-CR groups (0.4 ± 2.8% in the CR group vs. −0.6 ± 2.5% in the non-CR group, P-value = 0.046). Δ [LV GLS] showed satisfactory predictive performance for all-cause mortality (cut-off value = 0.8%, AUC 0.643, 95% CI [0.537–0.748]). Adding Δ [LV GLS] to the Mayo stage + pre-chemotherapy [LV GLS] model showed incremental prognostic value (C-index: 0.637 vs. 0.708; Relative Integrated Discrimination Index 0.07, P-value = 0.003; Net Reclassification Improvement 0.54, P-value < 0.001). Δ [LV GLS] showed good correlation with cardiac response (AUC 0.820, 95% CI [0.737–0.904]).ConclusionIn cardiac amyloidosis patients who underwent chemotherapy, longitudinal change of [LV GLS] after chemotherapy showed significant association with overall survival as well as cardiac response