207 research outputs found

    Global stability analysis of a hypersonic cone-cylinder-flare geometry

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    Characterizing the boundary layer transition to turbulence around realistic hypersonic vehicles is a challenging task due to the numerous parameters that affect the process. To address this challenge, the cone-cylinder-flare (CCF) geometry has been designed to provide a flow topology that captures various transition mechanisms observed on reentry objects, such as absolute and convective instabilities, which are dependent on the free stream conditions. In this study, a global linear stability analysis is performed on the CCF model at Mach=6.0 to investigate and map the dominant instabilities at wind tunnel flow conditions. We examine optimal responses and forcings computed using resolvent analysis, as well as global modes originating from the recirculation bubble at the cylinder flare junction. The effects of bluntness are assessed through analyses of both blunt and sharp configurations. Our results shed light on the linear flow mechanisms that promote the transition to turbulence around such hypersonic objects.Comment: Conference pape

    Le cimetière du cloître cathédral de Viviers: rites et mobilier funéraires

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    International audienceDépôt funéraire de poterie dans le cimetière du cloître de Viviers (Ardèche

    Le chantier médiéval dans le Sud-Est de la France: regard sur les techniques de construction et l’organisation du chantier à partir de quelques exemples (XIe-XIVe siècles)

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    The present article illustrates several aspects of the archaeological research on mediaeval construction in south-eastern France (11th-14th cent.) by studies in building archaeology led by the authors in various architectural and scientific contexts. It focuses on questions such as the know-how and its transfer, changes in the architectural project, the organization of the building process and its techniques and strategies, by analyzing the masonry and structure of the edifice and, in the case of the pope’s palace in Avignon, by combined research on the architecture and the written sources.Le présent article illustre différents aspects de la recherche sur la construction du XIe au XIVe siècle dans le Sud-Est de la France à l’exemple d’études monumentales menées par ses deux auteurs dans différents contextes architecturaux et scientifiques. Il aborde les questions du savoir-faire et de sa transmission, des changements de projet, et l’organisation du chantier, à partir des indices de la lecture des élévations et, dans le cas de la construction du palais des papes d’Avignon, de l’étude conjointe des sources écrites

    Le chantier médiéval dans le Sud-Est de la France: regard sur les techniques de construction et l’organisation du chantier à partir de quelques exemples (XIe-XIVe siècles)

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    The present article illustrates several aspects of the archaeological research on mediaeval construction in south-eastern France (11th-14th cent.) by studies in building archaeology led by the authors in various architectural and scientific contexts. It focuses on questions such as the know-how and its transfer, changes in the architectural project, the organization of the building process and its techniques and strategies, by analyzing the masonry and structure of the edifice and, in the case of the pope’s palace in Avignon, by combined research on the architecture and the written sources.<br><br>Le présent article illustre différents aspects de la recherche sur la construction du XIe au XIVe siècle dans le Sud-Est de la France à l’exemple d’études monumentales menées par ses deux auteurs dans différents contextes architecturaux et scientifiques. Il aborde les questions du savoir-faire et de sa transmission, des changements de projet, et l’organisation du chantier, à partir des indices de la lecture des élévations et, dans le cas de la construction du palais des papes d’Avignon, de l’étude conjointe des sources écrites

    Reservoir cells no longer detectable after a heterologous SHIV challenge with the synthetic HIV-1 Tat Oyi vaccine

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    BACKGROUND: Extra-cellular roles of Tat might be the main cause of maintenance of HIV-1 infected CD4 T cells or reservoir cells. We developed a synthetic vaccine based on a Tat variant of 101 residues called Tat Oyi, which was identified in HIV infected patients in Africa who did not progress to AIDS. We compared, using rabbits, different adjuvants authorized for human use to test on ELISA the recognition of Tat variants from the five main HIV-1 subtypes. A formulation was tested on macaques followed by a SHIV challenge with a European strain. RESULTS: Tat Oyi with Montanide or Calcium Phosphate gave rabbit sera able to recognize all Tat variants. Five on seven Tat Oyi vaccinated macaques showed a better control of viremia compared to control macaques and an increase of CD8 T cells was observed only on Tat Oyi vaccinated macaques. Reservoir cells were not detectable at 56 days post-challenge in all Tat Oyi vaccinated macaques but not in the controls. CONCLUSION: The Tat Oyi vaccine should be efficient worldwide. No toxicity was observed on rabbits and macaques. We show in vivo that antibodies against Tat could restore the cellular immunity and make it possible the elimination of reservoir cells

    Aujourd'hui le Moyen Age, archéologie et vie quotidienne en France Méridionale

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    [catalogue d'exposition], 1981-1983, Sénanque, Marseille, Arles, Toulon, Perpignan, Montpellier, Nice, GapInternational audienceCe catalogue d’exposition itinérante, fait la synthèse des principaux travaux du Laboratoire d’Archéologie Médiévale Méditerranéenne d’Aix-en-Provence (URA 6 du CRA CNRS) en 1981 réunis par l’équipe de Gabrielle Démians d’Archimbaud. L’habitat, les gestes de la vie quotidienne, le commerce et l’artisanat sont illustrés par les fouilles effectuées dans le Midi de la France, par de nombreux objets, en céramique, verre, pierre, os et métal ainsi que par les sources écrites, et les analyses de laboratoire, innovantes à cette époque

    Guylaine Dartevelle, Églises médiévales des Hautes-Alpes, Plein Cintre éditions, 1990. Préface de J. Thirion

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    Esquieu Yves. Guylaine Dartevelle, Églises médiévales des Hautes-Alpes, Plein Cintre éditions, 1990. Préface de J. Thirion. In: Bulletin Monumental, tome 150, n°1, année 1992. pp. 74-75

    Introduction

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    Esquieu Yves. Introduction. In: Espace ecclésial et liturgique au Moyen Âge. Lyon : Maison de l'Orient et de la Méditerranée Jean Pouilloux, 2010. pp. 67-74. (Travaux de la Maison de l'Orient et de la Méditerranée, 53

    Grasse : Cathédrale et palais épiscopal

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    Hautes- Alpes. Saint-André-de-Rosans

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    Esquieu Yves. Hautes- Alpes. Saint-André-de-Rosans. In: Bulletin Monumental, tome 150, n°1, année 1992. pp. 55-57
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