19 research outputs found

    Urticaria and infections

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    Urticaria is a group of diseases that share a distinct skin reaction pattern. Triggering of urticaria by infections has been discussed for many years but the exact role and pathogenesis of mast cell activation by infectious processes is unclear. In spontaneous acute urticaria there is no doubt for a causal relationship to infections and all chronic urticaria must have started as acute. Whereas in physical or distinct urticaria subtypes the evidence for infections is sparse, remission of annoying spontaneous chronic urticaria has been reported after successful treatment of persistent infections. Current summarizing available studies that evaluated the course of the chronic urticaria after proven Helicobacter eradication demonstrate a statistically significant benefit compared to untreated patients or Helicobacter-negative controls without urticaria (p < 0.001). Since infections can be easily treated some diagnostic procedures should be included in the routine work-up, especially the search for Helicobacter pylori. This review will update the reader regarding the role of infections in different urticaria subtypes

    Efficacy of intense pulsed light therapy for melasma

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    PubMed: 31500485[No abstract available

    Development of squamous cell carcinoma on an inflammatory linear verrucous epidermal nevus in the genital area

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    PubMed ID: 22838090Inflammatory linear verrucous epidermal nevus is a rare cutaneous disorder characterized by pruritic, erythematous, and verrucous papules and plaques along the lines of Blaschko. Histopathologically, there is a benign verrucous proliferation of keratinocytes together with alternating parakeratosis and orthokeratosis as well as inflammatory changes. We report a patient who developed squamous cell carcinoma (SCC) on an inflammatory linear verrucous epidermal nevus and we discuss the importance of regular follow-up of patients with epidermal nevi

    Geriatric patients in management of pigmented lesions: Should follow-up be recommended? [Pi·gmente lezyon degerlendi·ri·lmesi·nde geri·atri·k hasta: İzlem öneri·lmeli· mi·?]

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    Introduction: Dermatological follow-up is essential in management of pigmented lesions. Elderly people may have poor compliance to follow-up schedules because of immobilization and general health problems. In this study, we aimed to determine the general features of geriatric patients admitted to dermoscopy unit and evaluate their compliance both to follow-up and surgical recommendations. Materials and Method: All patients aged 65 years and over, who admitted to the dermoscopy unit between January 2003 and May 2008, were included in the study. Medical records of the patients were reviewed and age and gender of the patients, pigmented lesions and their localizations, and compliance to the follow-up schedule and surgical recommendations were evaluated retrospectively. Results: A total of 193 geriatric patients constituted 6.4% of 3016 patients admitted to dermoscopy unit in the same period. A total of 242 lesions were detected (158 of them were benign and 84 of them were premalignant/malignant). The most common lesions were seborrheic keratoses (27.3%), melanoma (17.8%), and melanocytic nevi (15.3%). A total of 130 patients (67.7%) were invited for follow-up and 29 of them (22.3%) were able to attend. A surgical procedure was recommended to a total of 99 patients (51.6%) in whom 82 (82.8%) followed the recommendations. Conclusion: Since the compliance may be difficult, it is recommended to consider the elderly as a special group and to avoid inviting them for follow-up if possible

    Analysis of bioconvection and oxytactic microorganisms in a porous cavity with nano-enhanced phase change materials and quadrant heater: Application of support vector regression based model

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    In this numerical study, two-dimensional simulations are performed to obtain the bioconvection flow in a quadrant heater located porous closed space saturated with nano-enhanced phase change material (NePCM). The Galerkin finite element method (GFEM) is employed to compute the governing equations for the considered system by developing a computer code. The study is performed for wide range of parameters as aspect ratio, Darcy number, Hartmann number, nanoparticle fraction, bioconvection Rayleigh number and natural convection Rayleigh number were tested. Also, the analysis is supported via artificial intelligent by using multiple support vector regression based model. The tests were performed with artificial intelligence on temperature values. After the analysis, it is found that radius of the curvilinear shaped heater plays role on both heat transfer and fluid flow, oxygen distribution, density of motile microorganism and heat capacity. Application of support vector machine technique gives good agreement with computational fluid dynamics results. Heat and mass transfer are improved with increasing of nanoparticle addition but decrease with increasing of strength of magnetic field. 2023 Elsevier LtdScopu
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