Carcinosarcoma of the breast: a case report

Meme karsinosarkomu, sarkom benzeri bileseni bulunan duktal tip karsinomayı ifade eden, malin epitelyal ve malin mezenkimal elemanların bir arada bulundugu bir malinitedir. Glandüler epitelin glandüler olmayan mezensimal dokuya farklanmasıyla ortaya çıkan ve seyrek görülen metaplastik meme kanserlerinin en seyrek görülen alt tipidir. Tüm meme malinitelerinin %1'inden azını olusturur. Literatürde karsinosarkomun radyolojik özelliklerinin degerlendirildigi sınırlı sayıda çalısma bulunmaktadır. Hastanemiz meme hastalıkları poliklinigine sol memede ele gelen kitle yakınmasıyla basvuran 44 yasında kadın hastada fizik bakı, mamografi ve ultrasonografi bulguları degerlendirildi. Mamografi ve ultrasonografide lobüle, karma solid ve kistik alanlar içeren kitle izlendi. Histopatolojik olarak karsinosarkom tanısı alan olguda parsiyel mastektomi ve aksiller diseksiyon yapıldı. Aksilladan çıkartılan 16 lenf nodunun biri metastatikti ve uzak metastaz saptanmadı. Bizim amacımız, nadir görülen bu tümörlerde radyolojik bulguları tanımlamak ve literatürü gözden geçirmektirCarcinosarcoma of the breast represents a ductal carcinoma which consists sarcoma like component. Both malign epithelial and malign mesenchymal elements exist together in the breast carcinosarcoma. Glandular epithelium differentiates into non-glandular mesenchymal tissue, a process called metaplasia. Metaplastic breast malignancy is a rare type of the breast cancer, moreover carcinosarcoma is the rarest subtype which is less than 1%of the whole breast cancers. There are limited studies and case reports of carcinosarcoma in literature. Fourtyfour aged woman applied to breast diseases polyclinic with palpable mass on her left breast. We evaluated the findings of the physical examination, mammography and ultrasound. On radiological evaluation we determined a lobulated complex mass with solid and cystic components. Histopathological examination resulted as carcinosarcoma. Lumpectomy and axillary dissection were performed. One axillary lymph node was metastatic out of 16 lymph nodes. There were no distant metastases. Our purpose is to define the radiologic findings about this rare tumour and to review the literature

Paget's disease of the breast: a case report

Our case is a twenty-eight-year-old female lady who admitted to dermatology clinic of our university hospital with itchy lesions on her nipple-areolar complex of her right breast. She had these symptoms and signs for nearly two years and these lesions did not respond to topical treatment. Punch biopsy of the lesion revealed Paget's disease of the breast and the patient was referred to general surgery department. A sharply demarcated erythematous lesion with yellowish crusts were found at the nipple-areolar complex of right breast. No lumps were palpated in both of the breast and axillary examination was normal bilaterally. Mammography of right breast revealed pleomorphic microcalcifications with suspicious features of malignancy in the upper outside quadrant of the breast. Vacuum-assisted biopsy was performed and histopathological examination revealed İntraductal carcinoma. Skin sparing mastectomy and an immediate breast reconstruction with a Becker prosthesis was performed. The incidence of Paget disease below the age of thirty and the clinicopathological features of the disease were discussed in this case report