Additional file 1: Table S1. of The impact of N-acetylcysteine and ascorbic acid in contrast-induced nephropathy in critical care patients: an open-label randomized controlled study

Classification of participants renal function according to RIFLE criteria at the entry study. Table S2. Medications with potential impact on renal function received by participants according to treatment group. Table S3. Univariate analysis of characteristics of survivors and non survivors. Table S4. CIN based on serum creatinine or cystatin-C changes or RIFLE score (between the day of radiocontrast material infusion and the day of CIN diagnosis). Table S5. Medications with potential impact on renal function received by participants according to the presence of CIN or not. Table S6. Fluid balance of patients included in the study according to the presence of CIN or not. (DOC 110 kb

Number of EPCs colonies per well from IPF patients with sPAP<35 mmHg and sPAP≥35 mmHg (p = 0.001).

<p>Number of EPCs colonies per well from IPF patients with sPAP<35 mmHg and sPAP≥35 mmHg (p = 0.001).</p

Endogenous VEGF expression in control subjects and IPF patients (p = 0.002).

<p>Endogenous VEGF expression in control subjects and IPF patients (p = 0.002).</p

Demographic data and blood cell counts of the study population.

<p>Data are expressed as mean±SD or as percentages.</p

Representative phase contrast microscopy of EPCs colony from an IPF patient.

<p>Original magnification 10x.</p

Number of EPCs colonies per well from control subjects and IPF patients (p<0.001).

<p>Number of EPCs colonies per well from control subjects and IPF patients (p<0.001).</p

Reactivities for CD31 and Flk-1 are shown in the left column (upper left for CD31 and lower left for FlK-1, respectively); the corresponding DAPI-images of attached EPCs are shown in the right column.

<p>No staining was observed when the primary antibody was replaced by the corresponding control mouse and rabbit IgG, respectively (data not shown). Original magnification, 20x.</p

Clinical characteristics and pulmonary function data of the study population.

<p>Data are expressed as mean±SD.</p>*<p>p<0.05 as compared with controls.</p

Relationship between the number of EPCs colonies per well and the alveolar to arterial gradient in the IPF patients (r = −0.750, p<0.001).

<p>Relationship between the number of EPCs colonies per well and the alveolar to arterial gradient in the IPF patients (r =  −0.750, p<0.001).</p