Strategies of Neuroprotection after Successful Resuscitation

Post-cardiac arrest syndrome (PCAS) incorporates post-cardiac arrest brain injury, post-cardiac arrest myocardial dysfunction, systemic ischemia/reperfusion syndrome and the precipitating pathology. Brain injury remains the leading cause of death in the post-cardiac arrest period. One of our main goals during post-resuscitation care is to guide a proper neuroprotective strategy. We are going to summarize the tools of neuroprotection in post-cardiac arrest therapy. The role of normoxia/normocapnia, normoglycemia, seizure control, sedation and pharmacologic strategies will be discussed in brief. The handling of temperature management and the management of hemodynamic variables to secure satisfactory cerebral perfusion will be worked out in details. Targeted temperature management is the main tool of neuroprotection in post-cardiac arrest therapy. We are going to conclude the principles of temperature control after successful resuscitation pointing out its beneficial effects. This method has also several complications that are going to be discussed highlighting its hemodynamic impacts. There is no evidence about target hemodynamic parameters during post-cardiac arrest syndrome to maintain cerebral perfusion neither about the most effective hemodynamic monitoring system. We are presenting preliminary data of our study where we investigate the effect of PiCCO™ (Pulse index Continous Cardiac Output) monitoring on the outcome in this patient group

Phytoextraction potential of wheat and study on the applicable ratio of converter sludgein some soil-sludge mixtures

Converter sludge is a by-product of the “steel industry”, at the wet cleaning process of the converter gas. The sludge might contain heavy metal oxides, more particularly of lead- (Pb) and zinc (Zn) oxides. Our aim is to investigate the accumulation ratio of these components within the different parts of some selected plants during the potential phytoremediation, phytoextraction processes. The investigation was implemented with the collaboration of students, who gained practical knowledge in sample preparation, analysis and data evaluation. The gained knowledge is a good complement to what the students have been learned in higher education and provides useful practical insights into environmental analysis. For the preparation of the laboratory experiment of this research, we made seedling growth tests with white mustard (Sinapis alba) seeds on the 20-40-60-80% mixtures of converter sludge and different kinds of soils. According to the germination results we determined that the most capable mixtures were the converter sludge and the loess mixtures. Wheat (Triticum aestivum) was chosen as a test plant for the experiments. The mixing ratio of the converter sludge was 5-10-15-20-25%. The metal content of the sludge-soil mixtures and the different parts of the wheat plants (shoot, root) were analyzed by XRF instrument. The results showed that the most effective and tolerable ratio of converter sludge can be the 10 and 15% in loamy soil mixtures. Wheat plants seem to be applicable on decreasing of the metal content from the sludge-soil mixtures. The decreasing average ratio was 50 % for Pb, 53 % for Zn, at using the lowest applied ratio into the soils. Further aim is to find other potential industrial plants for decreasing of the ratio toxic elements from the converter sludge

A kőzetjövesztés hatékonyságának növelése mikrohullámú kezeléssel: Rock Excavation Efficiency Improvement by Microwave Treatment

The paper deals with an overview of the state of art in using microwaves for assist hard rock cutting with mechanical means. The information provided consist on actual findings of researches previously performed in this field, from the literature review, which represents the start elements in the recently started MIWACUT project in the frame of ERAMIN-2 programme, financed jointly by EU and national research agency (UEFISCDI)

Classical Trajectory Monte Carlo simulation of coincidence experiments in electron impact ionization of helium

The state-to-state (exchange) interference of the autoionizing resonances of helium is studied in (e,2e) experiments. These studies are disturbed by the coincidence events caused by the direct ionization, so their decrease is desirable. For this reason, to mimic the experimental observation, we performed four-body classical trajectory Monte Carlo calculations. The calculations were done for 93.15 eV primary energy, where the exchange interference of the 2s2(1S) and 2p2(1D) autoionizing states of helium is expected. The yields of non-coincidence and coincidence events detected in various combinations of scattering geometry were calculated and compared with the experimental observations