Dynamic soil-structure interaction of reinforced concrete buried structures under the effect of dynamic loads using soil reinforcement new technologies. Soil-structure interaction of buried rigid and flexible pipes under geogrid-reinforced soil subjected to cyclic loads

Recent developments in constructions have heightened the need for protecting existing buried infrastructure. New roads and buildings may be constructed over already existing buried infrastructures e.g. buried utility pipes, leading to excessive loads threatening their stability and longevity. Additionally applied loads over water mains led to catastrophic damage, which result in severe damage to the infrastructure surrounding these mains. Therefore, providing protection to these existing buried infrastructure against increased loads due to new constructions is important and necessary. In this research, a solution was proposed and assessed, where the protection concept would be achieved through the inclusion process of geogrid-reinforcing layers in the soil cover above the buried infrastructure. The controlling parameters for the inclusion of geogrid-reinforcing layers was assessed experimentally and numerically. Twenty-three laboratory tests were conducted on buried flexible and rigid pipes under unreinforced and geogrid-reinforced sand beds. All the investigated systems were subjected to incrementally increasing cyclic loading, where the contribution of varying the burial depth of the pipe and the number of the geogrid-reinforcing layers on the overall behaviour of the systems was investigated. To further investigate the contribution of the controlling parameters in the pipe-soil systems performance, thirty-five numerical models were performed using Abaqus software. The contribution of increasing the amplitude of the applied cyclic loading, the number of the geogrid-reinforcing layers, the burial depth of the pipe and the unit-weight of the backfill soil was investigated numerically. The inclusion of the geogrid-reinforcing layers in the investigated pipe-soil systems had a significant influence on decreasing the transferred pressure to the crown of the pipe, generated strains along its crown, invert and spring-line, and its deformation, where reinforcing-layers sustained tensile strains. Concerning rigid pipes, the inclusion of the reinforcing-layers controlled the rebound that occurred in their invert deformation. With respect to the numerical investigation, increasing the number of the reinforcing-layers, the burial depth of the pipe and the unit-weight of the backfill soil had positive effect in decreasing the generated deformations, stresses and strains in the system, until reaching an optimum value for each parameter. Increasing the amplitude of the applied loading profile resulted in remarkable increase in the deformations, stresses and strains generated in the system. Moreover, the location of the maximum tensile strain generated in the soil was varied, as well as the reinforcing-layer, which suffered the maximum tensile strain.Government of Egyp

Numerical behaviour of buried flexible pipes in geogrid-reinforced soil under cyclic loading

YesThree-dimensional finite element models were executed and validated to investigate the performance of buried flexible high-density Polyethylene (HDPE) pipes, in unreinforced and multi-geogrid-reinforced sand beds, while varying pipe burial depth, number of geogrid-layers, and magnitude of applied cyclic loading. Geogrid-layers were simulated considering their geometrical thickness and apertures, where an elasto-plastic constitutive model represented its behaviour. Soil-geogrid load transfer mechanisms due to interlocked soil in-between the apertures of the geogrid-layer were modelled. In unreinforced and reinforced cases, pipe burial depth increase contributed to decreasing deformations of the footing and pipe, and the crown pressure until reaching an optimum value of pipe burial depth. On the contrary, the geogrid-layers strain increased with increasing pipe burial depth. A flexible slab was formed due to the inclusion of two-geogrid-layers, leading to an increase in the strain in the lower geogrid-layer, despite its lower deformation. Inclusion of more than two geogrid-layers formed a heavily reinforced system of higher stiffness, and consequently, strain distribution in the geogrid-layers varied, where the upper layer experienced the maximum strain. In heavily reinforced systems, increasing the amplitude of cyclic loading resulted in a strain redistribution process in the reinforced zone, where the second layer experienced the maximum strain

Experimental investigation into the effects of voids on the response of buried flexible pipes subjected to incrementally increasing cyclic loading

YesIn this study, large-scale fully instrumented laboratory tests were conducted to investigate the behaviour of buried flexible high-density polyethylene (HDPE) pipes, in sand beds with and without voids subjected to incrementally increasing cyclic loading. Voids with a predetermined size were created at one side of the springlines of the pipes, which were buried at variable depths, H, of 1.5, 2.0 and 2.5 times the diameter of the pipe, D. Results showed that increasing the pipe burial depth, H/D, contributed to decreasing the settlement of the footing, deformation of the pipe crown and invert, lateral displacement of the spring-line, and the stress and strain generated along the pipe crown and invert. Void presence led to a significant increase in the footing settlement, which ranged from 3 % up to 18 %, according to H/D. Furthermore, void presence led to a sharp increase in the crown, invert, and spring-line settlements, which ranged from 34 % to 52 %, 10 %–12.5 %, and 13 %–38 %, respectively. Increasing pipe burial depth was found to be highly effective in protecting buried pipes, minimising inevitable consequences of the presence of voids. However, this was combined with an increase in the pressure at the pipe spring-line that led to a positive horizontal support at the pipe’s spring-lines resulting in reducing pipe deformation

Protection of buried rigid pipes using geogrid-reinforced soil systems subjected to cyclic loading

YesThe performance of buried rigid pipes underneath geogrid-reinforced soil while applying incrementally increased cyclic loading was assessed using a fully instrumented laboratory rig. The influence of varying two parameters of practical importance was investigated; the pipe burial depth and the number of geogrid-layers. Measurements were taken for pipe deformation, footing settlement, strain in pipe and reinforcing layers, and pressure/soil stress on the pipe crown during various stages of cyclic loading. The research outcomes demonstrated a rapid increase in the rate of deformation of the pipe and the footing, and the rate of generated strain in the pipe and the geogrid-layers during the first 300 cycles. While applying further cycles, those rates were significantly decreased. Increasing the pipe burial depth and number of geogrid-layers resulted in reductions in the footing and the pipe deformations, the pressure on pipe crown, and the pipe strains. Redistribution of stresses, due to the inclusion of reinforcing layers, formed a confined zone surrounding the pipe providing it with additional lateral support. The pipe invert experienced a rebound, which was found to be dependent on pressure around the pipe and the degree of densification of the bedding layer. Data for strains measured in the geogrid-layers showed that despite the applied loading value and the pipe burial depth, the tensile strain in the lower geogrid-layer was usually higher than that measured in the upper layer

Buried flexible pipes behaviour in unreinforced and reinforced soils under cyclic loading

YesBecause of the recent worldwide construction expansion, new roads and buildings may be constructed over already existing buried infrastructures e.g. buried utility pipes, leading to excessive loads threatening their stability and longevity. Limited research studies are available to assess the effect of geogrid reinforcing layers inclusion on mitigating the additional stresses on buried structures due to cyclic loadings. In this research, large-scale fully instrumented laboratory tests were conducted to investigate the behaviour of flexible High-Density Polyethylene pipes (HDPE), in unreinforced and geogrid-reinforced sand, subjected to incrementally increasing cyclic loading, e.g. due to different vehicles capacities or load increase with passing time. Results illustrated that deformation rate in pipe and footing, strain generation rate in pipe and reinforcing layers are rapidly increased in the initial loading cycles, in particular during the first 300 cycles, and then the rate of change decreases significantly, as more cycles are applied. In the unreinforced case, increasing the pipe burial depth significantly reduced the generated deformation and strain in the pipe; however, it has a situational effect on the footing settlement, where it increased after pipe burial depth to its diameter ratio (H/D) of 2.5. In reinforced cases, deformation and strain significantly reduced with the increase in pipe burial depth and number of reinforcing layers. Measurement of strain illustrated that strain generated in the lower reinforcing layer is always higher than that recorded in the upper one, regardless pipe burial depth and value of applied load

Bacterial Outer Membrane Vesicles (OMVs)-Based Dual Vaccine for Influenza A H1N1 Virus and MERS-CoV

Vaccination is the most functional medical intervention to prophylactically control severe diseases caused by human-to-human or animal-to-human transmissible viral pathogens. Annually, seasonal influenza epidemics attack human populations leading to 290−650 thousand deaths/year worldwide. Recently, a novel Middle East Respiratory Syndrome Coronavirus emerged. Together, those two viruses present a significant public health burden in areas where they circulate. Herein, we generated a bacterial outer membrane vesicles (OMVs)-based vaccine presenting the antigenic stable chimeric fusion protein of the H1-type haemagglutinin (HA) of the pandemic influenza A virus (H1N1) strain from 2009 (H1N1pdm09) and the receptor binding domain (RBD) of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) (OMVs-H1/RBD). Our results showed that the chimeric antigen could induce specific neutralizing antibodies against both strains leading to protection of immunized mice against H1N1pdm09 and efficient neutralization of MERS-CoV. This study demonstrate that OMVs-based vaccines presenting viral antigens provide a safe and reliable approach to protect against two different viral infections