Additional file 1 of Behaviour change techniques used in lifestyle interventions that aim to reduce cancer-related fatigue in cancer survivors: a systematic review

Supplementary Material 1: Search queries and quality assessment of included studies

Determinants of adherence to recommendations for cancer prevention among Lynch Syndrome mutation carriers: A qualitative exploration

<div><p>Background</p><p>Lynch Syndrome (LS) mutation carriers are at high risk for various cancer types, particularly colorectal cancer. Adherence to lifestyle and body weight recommendations for cancer prevention may lower this risk. To promote adherence to these recommendations, knowledge on determinants of adherence in LS mutation carriers is needed. Therefore, this study aimed to identify determinants of adherence to lifestyle recommendations for cancer prevention in LS mutation carriers.</p><p>Methods</p><p>Five focus groups were conducted with DNA confirmed LS mutation carriers (n = 29). Transcripts were analyzed by thematic analysis, using the Health Belief Model (HBM) as a theoretical framework.</p><p>Results</p><p>Tolerance of an unhealthy lifestyle because of the desire to enjoy life and avoidance of LS dominating their life were most frequently reported as important barriers of adherence to the recommendations. Most important facilitators of adherence to the recommendations were enhancement of wellbeing and intolerance of unhealthy foods due to colon surgery.</p><p>Conclusions</p><p>This study provided a comprehensive overview of determinants of adherence to recommendations for cancer prevention. These determinants, of which some are typically and unique for LS mutation carriers, can be used to design a lifestyle intervention that meets the needs of LS mutation carriers.</p></div

Overview of reported facilitators and barriers of adherence to recommendations for cancer prevention that were perceived as most important by Lynch Syndrome mutation carriers and the frequency and the proportion with which they were mentioned.

<p>Overview of reported facilitators and barriers of adherence to recommendations for cancer prevention that were perceived as most important by Lynch Syndrome mutation carriers and the frequency and the proportion with which they were mentioned.</p

Characteristics of Lynch Syndrome mutation carriers who participated in the focus groups (n = 29).

<p>Characteristics of Lynch Syndrome mutation carriers who participated in the focus groups (n = 29).</p

Overview of all randomized controlled trials of folic acid with global DNA methylation as an endpoint.

1<p>conversion factor of 2.266 for folate from ng/mL to nmol/L.</p

Folic acid supplementation on global DNA methylation for the whole study population, for those with less than normal RBC folate status at baseline, low and high baseline methylation, and stratified by MTHFR C677T genotype.

1<p>values are given as median (inter-quartile range).</p>2<p>global DNA methylation is expressed as a percentage of 5-methylcytosines versus the total number of cytosines present in the genome.</p

Baseline characteristics of the population.

<p>Baseline characteristics of the population.</p

Socio-demographic and cancer-related characteristics of colorectal cancer survivors who were invited to participate in the current study (n = 1774), and of those who were included (n = 1198) vs. excluded (n = 576) from population for analyses¹.

<p>Socio-demographic and cancer-related characteristics of colorectal cancer survivors who were invited to participate in the current study (n = 1774), and of those who were included (n = 1198) vs. excluded (n = 576) from population for analyses<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0189178#t001fn001" target="_blank">¹</a>.</p

Socio-demographic, cancer-related, and health-related characteristics of colorectal cancer survivors (n = 1198) and associations with the need for dietary support.

<p>Socio-demographic, cancer-related, and health-related characteristics of colorectal cancer survivors (n = 1198) and associations with the need for dietary support.</p

Flow-chart of study participants.

<p>For the present study, cross-sectional data from a larger longitudinal study among colorectal cancer survivors are presented. A flow diagram of participants in this longitudinal study has been published elsewhere[<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0189178#pone.0189178.ref020" target="_blank">20</a>]. The present study involves data obtained from survey 3 in December 2012.</p