Final impact evaluation including socio-economic and gender variables, and farmers' knowledge and capacities regarding the technologies, completed

Annex 8 to final technical report : CIFSRF final technical report : Enhanced Preservation of Fruits Using Nanotechnology (CIFSRF Phase 2)This 2-page Annex to the larger project “Enhanced preservation of fruits using nanotechnology (CIFSRF Phase 2)” lists the 6 countries (Tanzania, Trinidad and Tobago, Canada, Sri Lanka, Kenya, India) where the hexanal/nanotechnology (Enhanced Freshness Formula, EFF) has been implemented. Major activities and key findings are presented

Automated pastures and the digital divide: how agricultural technologies are shaping labour and rural communities

A “digital revolution” in agriculture is underway. Advanced technologies like sensors, artificial intelligence, and robotics are increasingly being promoted as a means to increase food production efficiency while minimizing resource use. In the process, agricultural digitalization raises critical social questions about the implications for diverse agricultural labourers and rural spaces as digitalization evolves. In this paper, we use literature and field data to outline some key trends being observed at the nexus of agricultural production, technology, and labour in North America, with a particular focus on the Canadian context. Using the data, we highlight three key tensions observed: rising land costs and automation; the development of a high-skill/low-skilled bifurcated labour market; and issues around the control of digital data. With these tensions in mind, we use a social justice lens to consider the potential implications of digital agricultural technologies for farm labour and rural communities, which directs our attention to racial exploitation in agricultural labour specifically. In exploring these tensions, we argue that policy and research must further examine how to shift the trajectory of digitalization in ways that support food production as well as marginalized agricultural labourers, while pointing to key areas for future research—which is lacking to date. We emphasize that the current enthusiasm for digital agriculture should not blind us to the specific ways that new technologies intensify exploitation and deepen both labour and spatial marginalization

Experiencia de investigación colaborativa: un exitoso caso de intercambio internacional y multidisciplinario de conocimientos entre investigadores de Paraguay y Canadá

Este artículo relata la experiencia de colaboración e intercambio multidisciplinario en un proyecto de investigación, realizado en Paraguay, denominado: Alimentación, agricultura y formas de vida rurales en una comunidad del distrito de Piribebuy. En el trabajo colaboraron una antropóloga canadiense y tres profesoras paraguayas. En el proceso de la implementación y desarrollo del proyecto se han aprendido valiosas lecciones acerca del trabajo conjunto y de gerenciar un equipo multidisciplinario e internacional. La principal intensión de este artículo es reflejar dicho proceso de trabajo conjunto, los factores que determinan el éxito en una experiencia de intercambio internacional, y algunos desafíos

Impact of nasogastric tubes on swallowing physiology in older, healthy subjects: a randomized controlled crossover trial

Background & aims: The presence of a nasogastric tube (NGT) affects swallowing physiology but not function in healthy young adults. The swallowing mechanism changes with increasing age, therefore the impact of a NGT on swallowing in elderly individuals is likely to be different but is not yet known. The aims of this study were to determine the effects of NGTs of different diameter on (1) airway penetration-aspiration, (2) pharyngeal residue, and (3) pharyngeal transit, in older healthy subjects

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

IDRC doctoral research award / Bourse du CRDI aux chercheurs candidats au doctorat

Thesis, McMaster University, 200