Neoplasias quísticas de páncreas

Revisión bibliográfica acerca de las neoplasias quísticas de páncreas

School administrator preparation in Baja California

A team of US and Mexican researchers used focus groups to determine challenges faced by rural school directors who worked in isolated, poor communities. They had no preparation before becoming directors. Their stories express frustration with teachers who do not come to school on time and are not committed to education. Yet the directors throw themselves into their work and persist over the years. They ask for training in how to work with teachers, and they bring qualities of idealism and persistence to their work. The profiles of the directors suggest a changing dynamic on Hofstede's (2001) cultural dimension

Prevalence of post-intensive care syndrome in mechanically ventilated patients with COVID-19

Coronavirus disease 19 (COVID-19) patients usually require long periods of mechanical ventilation and sedation, which added to steroid therapy, favours a predisposition to the development of delirium and subsequent mental health disorders, as well as physical and respiratory sequelae. The aim of this study was to determine the prevalence of post-intensive care syndrome (PICS) at 3 months after hospital discharge, in a cohort of mechanically ventilated patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). An ambispective, observational study was conducted in three hospitals with intensive care unit (ICU) follow-up clinics. We studied adults who survived a critical illness due to SARS-CoV-2 infection requiring invasive mechanical ventilation. A physical (muscle strength and pulmonary function), functional [12-Item Short Form Health Survey (SF-12), and Barthel score], psychological [hospital anxiety and depression (HADS) and posttraumatic stress disorder symptom severity scales], and cognitive [Montreal cognitive assessment (MoCA) test] assessment were performed. A total of 186 patients were evaluated at 88 days (IQR 68–121) after hospital discharge. Mean age was 59 ± 12 years old, 126 (68%) patients were men, and median length of mechanical ventilation was 14 days (IQR 8–31). About 3 out of 4 patients (n = 139, 75%) met PICS criteria. Symptoms of cognitive and psychiatric disorders were found in 59 (32%) and 58 (31%) patients, respectively. Ninety-one (49%) patients had muscle weakness. Pulmonary function tests in patients with no respiratory comorbidities showed a normal pattern in 93 (50%) patients, and a restrictive disorder in 62 (33%) patients. Also, 69 patients (37%) were on sick leave, while 32 (17%) had resumed work at the time of assessment. In conclusion, survivors of critical illness due to SARS-CoV-2 infection requiring mechanical ventilation have a high prevalence of PICS. Physical domain is the most frequently damaged, followed by cognitive and psychiatric disorders. ICU follow-up clinics enable the assistance of this vulnerable populationThis study did not receive any funding or fnancial support. JMA and JV are funded by Grants from the Instituto de Salud Carlos III, Spain (CB06/06/1088, PI19/00141)

Políticas públicas para el desarrollo y la competitividad en la industria manufacturera

Las pequeñas y medianas empresas generan gran parte de los empleos en los países industrializados, sin embargo, la mayoría de los gobiernos muestran una gran falta de atención a las mismas, por considerarlas actividades poco importantes o de escaso aporte a sus economías. En México apenas se está iniciando el debate entre gobernantes, políticos y grandes empresarios, sobre la función de las pymes. Entre las cuestiones principales que se discuten están: ¿cuál es la importancia real de su contribución al crecimiento eocnómico de estos países?, ¿son un motor clave en la creación de empleos para las economías nacionales

Aplicación de la herramienta Socrative® para la evaluación en la asignatura "Repercusiones Bucales de las Enfermedades Sistémicas" en los alumnos de Odontología a través de dispositivos móviles. Fase I. Examen tipo test de preguntas dicotómicas

Incorporación de la herramienta interactiva Socrative® para la gestión de la participación de los alumnos y la evaluación rápida en tiempo real por parte del profesor en la asignatura "Repercusiones Bucales de las Enfermedades Sistémicas" en 3er Curso de Grado de Odontología.Se realizan preguntas y los alumnos contestan a través de sus dispositivos móviles, obteniendo un feedback inmediato de sus contestaciones

Cultura, innovación, internacionalización y vinculación de la Pyme con la Universidad : barómetro económico de la PYME 2011

Este barómetro corresponde al año 2011 y recoge información sobre: •Características generales de la empresa y expectativas. •Grado y capacidad de internacionalización de la empresa. •Relación de la empresa con el medio-ambiente. •Tecnología y grado de innovación de la empresa. •Organización, cultura empresarial y estrategia. •Vinculación de la empresa con la Universidad. •Evolución del rendimiento de la empresa respecto de la competenciaRegión de Murcia, Consejería de Universidades, Empresas e Innovación, INFO (Instituto de Fomento de la Regiñon de Murcia

Mis casos clínicos de especialidades odontológicas

Libro que muestra la atención de casos clínicos particulares referente a las diferentes especialidades odontológicasLibro que muestra la atención de casos clínicos particulares referente a las diferentes especialidades odontológicasUniversidad Autónoma de Campeche Universidad Autónoma del Estado de Hidalgo Universidad Autónoma del Estado de Méxic

A Large-Scale Genetic Analysis Reveals a Strong Contribution of the HLA Class II Region to Giant Cell Arteritis Susceptibility

We conducted a large-scale genetic analysis on giant cell arteritis (GCA), a polygenic immune-mediated vasculitis. A case-control cohort, comprising 1,651 case subjects with GCA and 15,306 unrelated control subjects from six different countries of European ancestry, was genotyped by the Immunochip array. We also imputed HLA data with a previously validated imputation method to perform a more comprehensive analysis of this genomic region. The strongest association signals were observed in the HLA region, with rs477515 representing the highest peak (p = 4.05 × 10−40, OR = 1.73). A multivariate model including class II amino acids of HLA-DRβ1 and HLA-DQα1 and one class I amino acid of HLA-B explained most of the HLA association with GCA, consistent with previously reported associations of classical HLA alleles like HLA-DRB1∗04. An omnibus test on polymorphic amino acid positions highlighted DRβ1 13 (p = 4.08 × 10−43) and HLA-DQα1 47 (p = 4.02 × 10−46), 56, and 76 (both p = 1.84 × 10−45) as relevant positions for disease susceptibility. Outside the HLA region, the most significant loci included PTPN22 (rs2476601, p = 1.73 × 10−6, OR = 1.38), LRRC32 (rs10160518, p = 4.39 × 10−6, OR = 1.20), and REL (rs115674477, p = 1.10 × 10−5, OR = 1.63). Our study provides evidence of a strong contribution of HLA class I and II molecules to susceptibility to GCA. In the non-HLA region, we confirmed a key role for the functional PTPN22 rs2476601 variant and proposed other putative risk loci for GCA involved in Th1, Th17, and Treg cell function