2 research outputs found
Adverse Events Associated with BNT162b2 and AZD1222 Vaccines in the Real World: Surveillance Report in a Single Italian Vaccine Center
Aim: Despite huge efforts in developing specific drugs, vaccination represents the only
effective strategy against COVID-19. Efficacy and safety of the COVID-19 vaccines were established
during clinical trials. Nonetheless, it is very important to perform continuous surveillance. This
observational study aimed to report potential Adverse Events Following Immunization (AEFI)
following the first dose of two different COVID-19 vaccines, BNT162b2 and AZD1222. Methods
and Results: Subjects who underwent vaccination at the vaccine center of the University Hospital
of Salerno, Italy, were interviewed using an ad hoc questionnaire. AZD-vac group (n = 175) who
received AZD1222 had a higher number of AEFI than the BNT-vac group (n = 1613) who received
BNT162b2 (83% vs. 42%). The most frequent AEFI associated with AZD1222 and BNT162b2 were
fever and pain at the injection site, respectively. The AZD-vac group used drugs to contrast AEFI
more frequently than the BNT-vac group. In the BNT-vac group, there was a higher incidence of AEFI
in women than in men (26.2% vs. 15.8%, p = 0.01), while no gender-related difference was observed
in the AZD-vac group. Conclusions: AZD1222 and BNT162b2 vaccines show a good safety profile.
Based on our results and literature data, there are no reasons to justify the reluctance that persists
towards immunization
Bacterial Epidemiology and Antimicrobial Resistance in the Surgery Wards of a Large Teaching Hospital in Southern Italy
Surgical infections represent an increasingly important problem for the National Health System. In this study we retrospectively evaluated the bacterial epidemiology and antimicrobial susceptibility of the microorganisms concerned as well as the utilization of antibiotics in the General and Emergency Surgery wards of a large teaching hospital in southern Italy in the period 2011-2013