436 research outputs found
The Thrift Savings Plan Experience: Implications for a Universal Asset Account Initiative
The Thrift Savings Plan Experience: Implications for a Universal Asset Account Initiativ
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A New Public Theology: Sanskrit and Society in Seventeenth-century South India
This dissertation documents the earliest stages in the emergence of the Smarta Saiva sectarian community of south India as captured by the theological writings of prominent Saiva theologians. I examine the sectarianization of Hinduism in microcosm by telling the story of a particular Hindu sect in the process of coming into being. The Smarta Saiva tradition of south India ranks among a handful of independent Hindu lineages that palpably dominates the public religious life of south India today. As a sectarian religious system, Smarta-Saivism comprises the institution of the Sankaracarya Jagadgurus and the extensive lay populace that has cultivated a relationship of personal devotion with these iconic figures. Historically speaking, however, the Smarta-Saiva tradition equally comprises the trailblazing theologians who first articulated the boundaries of the community, demarcating its distinct sectarian identity in contradistinction to its various Vaisnava and non-Smarta Saiva rivals. As it was these theologians whose pioneering inquiries crafted the systems of meaning that first gave birth to Smarta-Saivism as such, it is in their writings--their doctrine, polemic, ritual procedures, and devotional poetry--that this dissertation grounds its inquiry. My analysis centers on the textual contributions of Nilakantha Diksita--minister, poet laureate, and public theologian of Nayaka-period Madurai, and those connected with him by virtue of kinship, collegiality, or direct antagonism. Nilakantha and his immediate family and dialogical partners form the core of what I refer to as the "Smarta religious system" of the seventeenth century, culturally a direct antecedent of what we know today as south Indian Smarta-Saivism. My analysis takes the form of three parallel case studies, each of which illuminates a dynamic of intersection between intellectual discourse and religious culture that proved foundational to the religious landscape of south India up to the present day. Taken as a whole, these case studies illustrate the micro-dynamics of public theology, articulating key moments of the consolidation of south Indian Smarta identity and religiosity
A study of the medical-surgical clinical resources available for basic nursing students in "X" hospital
Thesis (M.S.)--Boston Universit
Paper Recycling and Academic Libraries
Paper recycling is a fitting endeavor for an academic library. A literature review and a feasibility study revealed that the benefits can include reduced costs to the university, librarians\u27 involvement in a cooperative campus-wide project and improved staff morale throughout the library
Beliefs about worry and pain amongst adolescents with and without chronic pain
Funding: This work was supported by Bath Spa University funding (grant number HEQREW, to EW). Acknowledgments: We sincerely thank all the young people who completed our survey.Peer reviewedPostprin
NWSA News and Views
The reports in this issue on the finances of the First NWSA Convention and on NWSA\u27s Project to Improve Service Learning in Women\u27s Studies might serve as Fall reports from the National Office.
Both are about NWSA activities derived from our broad definition of women\u27s studies; both announce long-awaited good news of what we hope will be the first of many successful conventions and projects that will bring women\u27s studies practitioners together to share the work of transforming curriculum and educational institutions
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Proteomic analyses of primary human villous trophoblasts exposed to flame retardant BDE-47 using SWATH-MS
Polybrominated diphenyl ethers (PBDEs) are a class of brominated flame retardants and recognized developmental toxicants that are detectable in placental tissues. Higher levels of in utero PBDE exposure have been associated with an increased risk of adverse birth outcomes. During pregnancy, cytotrophoblasts (CTBs) from the placenta play critical roles in the formation of the maternal-fetal interface via uterine invasion and vascular remodeling. The differentiation of these cells towards an invasive phenotype is crucial for proper placental development. We previously have shown that BDE-47 can impact CTB viability and hinder the ability of these cells to migrate and invade. To expand on potential toxicological mechanisms, we utilized quantitative proteomic approaches to identify changes in the global proteome of mid-gestation primary human CTBs after exposure to BDE-47. Using sequential window acquisition of all theoretical fragment-ion spectra (SWATH), we identified 3024 proteins in our CTB model of differentiation/invasion. Over 200 proteins were impacted as a function of BDE-47 exposure (1 μM and 5 μM) across the treatment period (15, 24, and 39 h). The differentially expressed molecules displayed time- and concentration-dependent changes in expression and were enriched in pathways associated with aggregatory and adhesive processes. Network analysis identified CYFIP1, a molecule previously unexplored in a placental context, to be dysregulated at BDE-47 concentrations previously seen to impact CTB migration/invasion. Our SWATH-MS dataset thus demonstrates BDE-47 impacts the global proteome of differentiating CTBs and serves as a valuable resource for further understanding of the relationship between environmental chemical exposures and placental development and function. AVAILABILITY OF DATA AND MATERIAL: Raw chromatograms are deposited on the MassIVE proteomic database (https://massive.ucsd.edu) under accession number MSV000087870. Normalized relative abundances are also available as Table S1
Continuous low-dose antibiotic prophylaxis for adults with repeated urinary tract infections (AnTIC): a randomised, open-label trial
Funder: UK National Institute for Health Research. Open Access funded by Department of Health UK Acknowledgments We thank all the participants for their commitment to the study, Sheila Wallace for updating the systematic review, members of the Trial Steering Committee and members of the Data Monitoring Committee for their valuable guidance. We thank the National Health Service organisations, principal investigators and local research staff who hosted and ran the study at site. We thank the Health Technology Assessment Programme of the UK NIHR for funding the study (no. 11/72/01). The views expressed are those of the authors and not necessarily those of the NHS, the NIHR, or the UK Government Department of Health. A full report of the study30 has been published by the NIHR Library.Peer reviewedPublisher PD
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