Fiber amplification of pulse bursts up to 20 mu J pulse energy at 1 kHz repetition rate

Cataloged from PDF version of article.We demonstrate burst-mode operation of a polarization-maintaining Yb-doped fiber amplifier. Groups of pulses with a temporal spacing of 10 ns and 1 kHz overall repetition rate are amplified to an average pulse energy of similar to 20 mu J and total burst energy of 0.25 mJ. The pulses are externally compressed to similar to 400 fs. The amplifier is synchronously pulsed-pumped to minimize amplified spontaneous emission between the bursts. We characterize the influence of pump pulse duration, pump-to-signal delay, and signal burst length. (C) 2011 Optical Society of Americ

Ketoprofen gel improves low back pain in addition to IV dexketoprofen: a randomized placebo-controlled trial

Objective Oligoanalgesia is common in emergency departments (EDs), and pain management is of concern for ED physicians. The aim of this study was to reveal the effect of ketoprofen gel in patients presenting with mechanical low back pain to the ED. Method All the study patients received intravenous dexketoprofen additional to study drugs. After dexketoprofen, 2 g of 2.5% ketoprofen gel or placebo was administered to the site with pain and tenderness. Pain relief at 15 and 30 minutes was measured by visual analog scale scores. Rescue drug need and adverse effects were also recorded. Results A total of 140 patients were enrolled into the study. The mean age of the study patients was 35 ± 12, and 56% (n = 79) of them were male. The mean pain reduction at 30 minutes was 52 ± 18 for ketoprofen gel and 37 ± 17 for placebo, and ketoprofen gel was better than placebo at 30 minutes (mean difference, 16 mm; 95% confidence interval, 10-21). Ten patients (14%) in the placebo group and 2 patients (3%) in the ketoprofen gel group needed rescue drug (P = .35). Conclusion Ketoprofen gel improves pain in patients presenting with mechanical low back pain to ED at 30 minutes in addition to intravenous dexketoprofen when compared to placebo. © 2016 Elsevier Inc

83 W, 3.1 MHz, square-shaped, 1 ns-pulsed all-fiber-integrated laser for micromachining

Cataloged from PDF version of article.We demonstrate an all-fiber-integrated laser based on off-the-shelf components producing square-shaped, 1 ns-long pulses at 1.03 mu m wavelength with 3.1 MHz repetition rate and 83 W of average power. The master-oscillator power-amplifier system is seeded by a fiber oscillator utilizing a nonlinear optical loop mirror and producing incompressible pulses. A simple technique is employed to demonstrate that the pulses indeed have a random chirp. We propose that the long pulse duration should result in more efficient material removal relative to picosecond pulses, while being short enough to minimize heat effects, relative to nanosecond pulses commonly used in micromachining. Micromachining of Ti surfaces using 0.1 ns, 1 ns and 100 ns pulses supports these expectations. (C) 2011 Optical Society of Americ

Three-dimensional modelling of the femur and humerus in adult male guinea pigs (guinea pig) with computed tomography and some biometric measurement values

Background: Guinea pig is a species belonging to the Caviidae family of the Rodentia order and is frequently used in experimental studies. Biomedical imaging methods are used in the diagnosis and treatment of many diseases in medicine. Among these methods, computed tomography (CT) is one of the most important imaging methods. In this study, it was aimed to perform the three-dimensional (3D) modelling of the CT images, obtained from the humerus and femur in the guinea pigs, via the MIMICS programme, and to make some biometric measurements regarding the bones over these models. Materials and methods: In the present study, 12 male adult guinea pigs were used. The soft tissue on the humerus and femur bones of the guinea pigs was removed. After this procedure, CT images at a 0.5 mm-thickness were obtained from the animals. The images were recorded in DICOM format. Then, the reconstruction process was performed from the images by using the 3D modeling programme MIMICS® 13.1. On the 3D model of the humerus and femur (right-left), volumes, surface areas and lengths as well as other biometric parameters were measured separately, and the values were recorded. In addition, measurements of the bones were made with the help of a digital calliper. Results: Among the parameters obtained from 3D models, a statistical difference was observed between the right and left cortical thicknesses of the femur from the measurements of calliper and the right and left humerus volumes (p < 0.05); whereas, no statistical difference was found in other parameters of both measurements (p > 0.05). Conclusions: It can be stated that CT and 3D modelling can be used for the measurement of some parameters in the long bones of the guinea pigs

Fiber amplification of pulse bursts up to 20 μj pulse energy at 1 kHz repetition rate

We demonstrate burst-mode operation of a polarization-maintaining Yb-doped fiber amplifier. Groups of pulses with a temporal spacing of 10 ns and 1 kHz overall repetition rate are amplified to an average pulse energy of ∼20 μJ and total burst energy of 0:25 mJ. The pulses are externally compressed to ∼400 fs. The amplifier is synchronously pulsed-pumped to minimize amplified spontaneous emission between the bursts. We characterize the influence of pump pulse duration, pump-to-signal delay, and signal burst length. © 2011 Optical Society of America

Texturing of titanium (Ti6Al4V) medical implant surfaces with MHz-repetition-rate femtosecond and picosecond Yb-doped fiber lasers

Cataloged from PDF version of article.We propose and demonstrate the use of short pulsed fiber lasers in surface texturing using MHz-repetition-rate, microjoule- and sub-microjoule-energy pulses. Texturing of titanium-based (Ti6Al4V) dental implant surfaces is achieved using femtosecond, picosecond and (for comparison) nanosecond pulses with the aim of controlling attachment of human cells onto the surface. Femtosecond and picosecond pulses yield similar results in the creation of micron-scale textures with greatly reduced or no thermal heat effects, whereas nanosecond pulses result in strong thermal effects. Various surface textures are created with excellent uniformity and repeatability on a desired portion of the surface. The effects of the surface texturing on the attachment and proliferation of cells are characterized under cell culture conditions. Our data indicate that picosecond-pulsed laser modification can be utilized effectively in low-cost laser surface engineering of medical implants, where different areas on the surface can be made cell-attachment friendly or hostile through the use of different patterns. (C) 2011 Optical Society of Americ

Doping management for high-power fiber lasers: 100 W, few-picosecond pulse generation from an all-fiber-integrated amplifier

Cataloged from PDF version of article.Thermal effects, which limit the average power, can be minimized by using low-doped, longer gain fibers, whereas the presence of nonlinear effects requires use of high-doped, shorter fibers to maximize the peak power. We propose the use of varying doping levels along the gain fiber to circumvent these opposing requirements. By analogy to dispersion management and nonlinearity management, we refer to this scheme as doping management. As a practical first implementation, we report on the development of a fiber laser-amplifier system, the last stage of which has a hybrid gain fiber composed of high-doped and low-doped Yb fibers. The amplifier generates 100 W at 100 MHz with pulse energy of 1 mu J. The seed source is a passively mode-locked fiber oscillator operating in the all-normal-dispersion regime. The amplifier comprises three stages, which are all-fiber-integrated, delivering 13 ps pulses at full power. By optionally placing a grating compressor after the first stage amplifier, chirp of the seed pulses can be controlled, which allows an extra degree of freedom in the interplay between dispersion and self-phase modulation. This way, the laser delivers 4.5 ps pulses with similar to 200 kW peak power directly from fiber, without using external pulse compression. (C) 2012 Optical Society of Americ

Fiber amplification of pulse bursts at low repetition rates via synchronous pulsed pumping

We report, for the first time, amplification of pulse-bursts in Yb-doped fiber at repetition rates as low as 200 Hz for applications to accelerators and material processing. Synchronous pulsed pumping allows suppression of ASE generation. © 2011 Optical Society of America

Seismic anisotropy inferred from direct <i>S</i>-wave-derived splitting measurements and its geodynamic implications beneath southeastern Tibetan Plateau

The present study deals with detecting seismic anisotropy parameters beneath southeastern Tibet near Namcha Barwa Mountain using the splitting of direct S waves. We employ the reference station technique to remove the effects of source-side anisotropy. Seismic anisotropy parameters, splitting time delays, and fast polarization directions are estimated through analyses of a total of 501 splitting measurements obtained from direct S waves from 25 earthquakes ( ≥  5.5 magnitude) that were recorded at 42 stations of the Namcha Barwa seismic network. We observe a large variation in time delays ranging from 0.64 to 1.68 s, but in most cases, it is more than 1 s, which suggests a highly anisotropic lithospheric mantle in the region. A comparison between direct S- and SKS-derived splitting parameters shows a close similarity, although some discrepancies exist where null or negligible anisotropy has been reported earlier using SKS. The seismic stations with hitherto null or negligible anisotropy are now supplemented with new measurements with clear anisotropic signatures. Our analyses indicate a sharp change in lateral variations of fast polarization directions (FPDs) from consistent SSW–ENE or W–E to NW–SE direction at the southeastern edge of Tibet. Comparison of the FPDs with Global Positioning System (GPS) measurements, absolute plate motion (APM) directions, and surface geological features indicates that the observed anisotropy and hence inferred deformation patterns are not only due to asthenospheric dynamics but are a combination of lithospheric deformation and sub-lithospheric (asthenospheric) mantle dynamics. Direct S-wave-based station-averaged splitting measurements with increased back-azimuths tend to fill the coverage gaps left in SKS measurements

Micromachining with square-Shaped 1 ns-Long pulses from an all-Fiber Yb-Doped laser-Amplifier system

We demonstrate micromachining with 1ns-long pulses from an all-fiber laser. Fiber lasers generating uncompressible long pulses have been ignored as undesired operational modes, however their robust, low-repetition-rate operation is well suited to micromachining. © 2011 Optical Society of America