Cutaneous Manifestations of Inflammatory Bowel Disease

Cutaneous lesions are among the most frequent extraintestinal manifestations of inflammatory bowel disease (IBD). They may precede, occur with or postdate the onset of the intestinal disease and can significantly contribute to the morbidity and impairment of the overall quality of life of the affected patients. In this article, the cutaneous manifestations of IBD are reviewed with particular emphasis on their clinicopathological and therapeutic aspects

Successful Treatment of Lichen Striatus With Occlusive Imiquimod 5% Cream

Lichen striatus is an uncommon acquired linear inflammatory skin disorder, that preferentially occurs in children. We report a 15-year-old girl with a 16-month history of lichen striatus. Topical application of imiquimod 5% cream twice-daily under occlusion led to resolution of the intense pruritus within 6 days of treatment and to complete remission of the cutaneous lesions after 5 weeks of treatment. The patient experienced no local or systemic side effects. She has been followed-up for 13 months and revealed no evidence of recurrence. Topical imiquimod may be an effective and safe alternative treatment for recalcitrant lichen striatus