517 research outputs found
Semiclassical Strings Probing NS5 Brane Wrapped on S^5
We study little string theory on R^1 x S^5, defined by a theory which lives
on type IIA N NS5 branes wrapped on S^5, using its supergravity dual. In
particular we study semiclassical rotating closed strings in this background.
We also consider Penrose limit of this background that leads to a plane wave on
which string theory is exactly solvable.Comment: 14 pages, Latex, v2: typos corrected, Refs. added, v3: typos
correcte
Algebraic approach to the Hulthen potential
In this paper the energy eigenvalues and the corresponding eigenfunctions are
calculated for Hulthen potential. Then we obtain the ladder operators and show
that these operators satisfy SU(2) commutation relation.Comment: 8 Pages, 1 Tabl
Optimised Traffic Flow at a Single Intersection: Traffic Responsive signalisation
We propose a stochastic model for the intersection of two urban streets. The
vehicular traffic at the intersection is controlled by a set of traffic lights
which can be operated subject to fix-time as well as traffic adaptive schemes.
Vehicular dynamics is simulated within the framework of the probabilistic
cellular automata and the delay experienced by the traffic at each individual
street is evaluated for specified time intervals. Minimising the total delay of
both streets gives rise to the optimum signalisation of traffic lights. We
propose some traffic responsive signalisation algorithms which are based on the
concept of cut-off queue length and cut-off density.Comment: 10 pages, 11 eps figs, to appear in J. Phys.
Orexin Receptor Antagonism, a New Sleep-Enabling Paradigm: A Proof-of-Concept Clinical Trial
Peer reviewe
Economics methods in Cochrane systematic reviews of health promotion and public health related interventions.
Peer reviewedPublisher PD
Descriptive epidemiology of salivary gland neoplasms in Nigeria: An AOPRC multicenter tertiary hospital study
Objectives: Accurate diagnosis of salivary gland neoplasms (SGN) in many centers in
Africa is limited by poor diagnostic resources and ancillary services. Hence, we have
carried out a multicenter epidemiological study to understand the true burden of
SGN in Nigeria.
Method: In this descriptive cross‐sectional study, we have deployed resources available
to members of the African Oral Pathology Consortium (AOPRC) to examine the
burden of salivary gland lesions in Nigeria, using a multicenter approach. Data from
seven major tertiary health institutions in northern, western, and southern Nigeria
were generated using a standardized data extraction format and analyzed using the
Epi‐info software (Version 7.0, Atlanta, USA).
Result: Of the 497 cases examined across the seven centers, we observed that SGN
occurred more in females than males. Overall, pleomorphic salivary adenoma (PA)
was found to be the most common. PA was found to be the commonest benign SGN
while adenocystic carcinoma (ADCC) was the commonest malignant SGN. Regional
variations were observed for age group, diagnosis, and gender distribution. Significant statistical differences were found between males and females for malignant SGNs (p‐value=0.037).
Conclusion: We found regional variation in the pattern of distribution of SGN in
Nigeria. This is the largest multicenter study of SGN in Nigeria, and our findings are
robust and representative of the epidemiology of this neoplasm in Nigeria
The state of the Martian climate
60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic traits, we performed meta-analyses of 21 genome-wide association studies informative for fasting glucose, fasting insulin and indices of beta-cell function (HOMA-B) and insulin resistance (HOMA-IR) in up to 46,186 nondiabetic participants. Follow-up of 25 loci in up to 76,558 additional subjects identified 16 loci associated with fasting glucose and HOMA-B and two loci associated with fasting insulin and HOMA-IR. These include nine loci newly associated with fasting glucose (in or near ADCY5, MADD, ADRA2A, CRY2, FADS1, GLIS3, SLC2A2, PROX1 and C2CD4B) and one influencing fasting insulin and HOMA-IR (near IGF1). We also demonstrated association of ADCY5, PROX1, GCK, GCKR and DGKB-TMEM195 with type 2 diabetes. Within these loci, likely biological candidate genes influence signal transduction, cell proliferation, development, glucose-sensing and circadian regulation. Our results demonstrate that genetic studies of glycemic traits can identify type 2 diabetes risk loci, as well as loci containing gene variants that are associated with a modest elevation in glucose levels but are not associated with overt diabetes
Towards an optimal therapy strategy for myogenous TMD, physiotherapy compared with occlusal splint therapy in an RCT with therapy-and-patient-specific treatment durations
Appendix. Threshold of signs and symptoms. Post-hoc power analysis on measures of effectiveness. Two-way ANOVA statistical analysis for pain intensity. Rules for progressing and ending splint therapy. Rules for progressing and ending physiotherapy. A stepped-care model including two possible therapies. (PDF 86 kb
Moderate alcohol consumption increases insulin sensitivity and ADIPOQ expression in postmenopausal women: a randomised, crossover trial
Aims/hypothesis To determine whether 6 weeks of daily, moderate alcohol consumption increases expression of the gene encoding adiponectin (ADIPOQ) and plasma levels of the protein, and improves insulin sensitivity in postmenopausal women. Methods In a randomised, open-label, crossover trial conducted in the Netherlands, 36 apparently healthy postmenopausal women who were habitual alcohol consumers, received 250 ml white wine (~25 g alcohol/day) or 250 ml of white grape juice (control) daily during dinner for 6 weeks. Randomisation to treatment allocation occurred according to BMI. Insulin sensitivity and ADIPOQ mRNA and plasma adiponectin levels were measured at the end of both periods. Insulin sensitivity was estimated using the homeostasis model assessment of insulin resistance (HOMA-IR). Levels of ADIPOQ mRNA in subcutaneous adipose tissue were determined by RT-PCR. Results All subjects completed the study. Six weeks of white wine consumption reduced fasting insulin (mean¿±¿SEM 40.0¿±¿3.4 vs 46.5¿±¿3.4 pmol/l; p
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