891 research outputs found
Detection of human papillomavirus DNA sequences in oral lesions using polymerase chain reaction
The purpose of the present study was to estimate the frequency of HPV DNA in four groups of oral lesions, including oral squamous cell carcinoma. Sixty paraffin-embedded oral tissue samples were examined for the presence of HPV DNAs using the PCR technique. These specimens were obtained from patients with oral squamous cell carcinoma (OSCC), leukoplakia, oral lichen planus (OLP), and pyogenic granuloma (PG). Consensus primers for L1 region (MY09 and MY11) and specific primers were used for detection of HPV DNA sequences in this study. we detected HPV DNA in 60% (9 out of 15) of OSCCs, 26.7% (4 out of 15) of leukoplakia, 13.3% (2 out of 15) of OLPs, and 6.7% (1 out of 15) of PGs. Statistical analysis showed that the prevalence of HPV in OSCC was significantly higher than other groups (P < 0.05). The frequency of HPV-16 and 18 detection in OSCC samples were 40% and 20%, respectively. The prevalence of these high risk HPVs was significantly higher in OSCC group (P < 0.05). The results of the present study show a successive increase of detection rate of HPV-16 and 18 DNAs from low level in samples of pyogenic granuloma and non-premalignant or questionably premalignant lesions of OLP to premalignant leukoplakia and to OSCC. © 2007 Tehran University of Medical Sciences. All rights reserved
The Study on Relation of Human Papillomavirus High Risk Types with Bladder Transitional Cell Carcinoma
En este programa se hablará sobre las telecomunicaciones, se les contará qué es, como mueve al mundo actualmente y como la Universidad Militar Nueva Granada se prepara para formar a los mejores profesionales en este campo
Control of spatiotemporal rogue waves by harmonic pump modulation in a semiconductor laser with a saturable absorber
Through numerical simulations, statistical and dynamical properties of extreme events in a broad-area semiconductor laser with intracavity saturable absorber are investigated. By inclusion of a diffusion coefficient for the field, formation of rogue waves in a state of extended turbulence is studied and shown to be affected by harmonic perturbations. In particular, we propose a control technique based on periodic modulation of the pump parameter which can either drive the state of the system closer to or away from the chaotic attractors respectively enhancing or suppressing the generation of rogue waves. By statistical and dynamical analysis of the events in terms of intensity and optical gain, we show that when the system is under resonant modulation with frequency close to that of the dominant oscillations in the turbulent state (which is equal to the relaxation oscillation frequency typical of semiconductor lasers), more rogue waves are triggered with larger intensities and shorter lifetimes. On the other hand, off-resonant modulations restrain the formation of rogue waves where they appear in lower intensities and longer lifetimes. An example of special cases where the proposed scheme can completely forbid or allow the emission of rogue waves is also presented
Metallogeny of Serpentinite-Hosted Magnetite Deposits : Hydrothermal Overgrowth on Chromite or Metamorphic Transformation of Chromite?
Peculiar and rare occurrences of serpentinite-hosted magnetite deposits with mineable sizes are found in the Mesozoic ophiolites of Greece (Skyros), Iran (Nain and Sabzevar) and Oman (Aniba). These deposits have diverse thickness (from a few centimeters up to 50 m) and length (2 to >500 m). Magnetite ores show variable textures, including massive, nodular and banded ores, veins, net and fine-grained disseminations in serpentinites. Intriguingly, the investigated magnetite deposits can be mistaken for chromitite pods. Serpentinite-hosted magnetite deposits show three modes of occurrences including: (i) boulders strewn across the serpentinites (i.e. Skyros Island) (ii) ore bodies along the nonconformity contacts between serpentinites and limestones (i.e. Aniba); (iii) irregular and discontinuous trails of massive and semi-massive ore bodies within highly sheared serpentinite masses (i.e. Nain; Sabzevar). In all of these magnetite ore bodies, relicts of chromian spinel grains are occasionally enclosed in magnetite crystals. The chemistry of Cr-spinel relics found in these magnetite bodies are comparable to those of accessory Cr-spinels in the surrounding serpentinized peridotites. BSE images and elemental mapping revealed that magnetite occurs as a nucleation on chromian spinels but not being involved in reaction either with chromite or ferritchromite. Low-grade metamorphic transformation of chromite into Fe-chromite is documented along the cracks and fractures of a few chromite grains. Generally, magnetite has typical hydrothermal compositions, characterized by low Cr, V and Ti and high Mg and Mn. It is crucial to note that a few magnetite grains with metamorphic origin are characterized by high Cr and low Ti and Ni. The potential source of iron is essentially the Fe-rich olivine, We believe that multi-episodic serpentinization of peridotite systems at high fluid-rock ratios is the main process responsible for precipitation of magnetite at ore levels whereas low-grade metamorphic transformation of chromite to magnetite has minor contribution. Cumulative factors in generation of these deposits are modal volume of mantle olivine, peridotite composition, fluid chemistry, fluid-rock ratio, mechanisms of transportation and precipitation, structural controls such as cracks and shear zones
Extra-hepatic fascioliasis with peritoneal malignancy tumor feature
Fascioliasis is a zoonose parasitic disease
caused by Fasciola hepatica and Fasciola gigantica and is
widespread in most regions of the world. Ectopic fascioliasis
usually caused by juvenile Fasciola spp., but in
recent years a few cases of tissue-embedded ova have been
reported from different endemic areas. A 79-year-old Iranian
man resident in Eird-e-Mousa village from Ardabil
Province, north-west of Iran, complained with abdominal
pain, nausea, and intestinal obstruction symptoms referred
to Ardabil Fatemi hospital. In laparotomy multiple intestinal
masses with peritoneal seeding resembling of a
malignant lesion were seen. After appendectomy and peritoneal
mass biopsy with numerous intraperitoneal adenopathy,
paraffin embedded blocks were prepared from
each tissues. A blood sample was taken from the patient
5 months later for serological diagnosis. Histopathological
examination of sections showed fibrofatty stroma with
dense mixed inflammatory cells infiltration and fibrosis in
peritoneal masses. Large numbers of ova of Fasciola spp.
were noted with typical circumscribed granulomas. Despite
of anti-fasciola treatment, IHA test for detecting anti F.
hepatica antibodies was positive 5 months after surgery
with a titer of 1/128. Due to multiple clinical manifestation
of extra-hepatic fascioliasis, its differential diagnosis from
intraperitoneal tumors or other similar diseases should be
considered
Baby Skyrme models for a class of potentials
We consider a class of (2+1) dimensional baby Skyrme models with potentials
that have more than one vacum. These potentials are generalisation of old and
new baby Skyrme models;they involve more complicated dependence on phi_3.We
find that when the potential is invariant under phi_3 -> -phi_3 the
configuration corresponding to the baby skyrmions lying "on top of each other"
are the minima of the energy. However when the potential breaks this symmetry
the lowest field configurations correspond to separated baby skyrmions. We
compute the energy distributions for skyrmions of degrees between one and eight
and discuss their geometrical shapes and binding energies. We also compare the
2-skyrmion states for these potentials. Most of our work has been performed
numerically with the model being formulated in terms of three real scalar
fields (satisfying one constraint).Comment: LaTeX, 14 pages, 10 figure
Prevalence of ESBLs in Acinetobacter baumannii isolated from intensive care unit (ICU) of Ghaem hospital, Mashhad, Iran
Acinetobacter baumannii is an important opportunistic pathogen that mainly infects critically patients in intensive care units (ICU). The production of plasmid-mediated extended-spectrum b-lactamases (ESBLs) is one of the most important mechanisms of resistance against b-lactam antibiotics. This study aimed to evaluate the prevalence of ESBLs in A. baumannii isolated from ICU of Ghaem hospital, Mashhad, Iran. A total of 140 A. baumannii isolates recovered from hospitalized patients in ICU of Ghaem hospital in Mashhad city from December 2014 to March 2015. Identification of A. baumannii isolates carried out using biochemical laboratory methods and then confirmed by OXA-51 PCR screening. Susceptibility testing performed using disk diffusion (Kirby-Bauer) method as recommended by CLSI guidelines. A. baumannii isolates screened for production of ESBLs using combination disk test. blaPER, blaGES, blaTEM, blaSHV, blaCTX, blaVEB and blaOXA-10 beta-lactamase genes detected using conventional PCR. The most antibacterial resistance was against cefuroxime (99.3%) and colistin was the most effective antibiotic. None of the isolates were ESBL producer by combination disk test. However, results of PCR revealed that the prevalence of blaPER, blaGES and blaTEM genes were 7.1%, 4.3% and 27.1%, respectively. blaCTX, blaVEB, and blaOXA-10 were not found in any of isolates. According to the results, the high resistance was seen against selected antibiotics and the phenotypic tests are not sufficient alone for determination of ESBLs producer of A. baumannii isolates. So, molecular tests are also necessary for detection of these enzymes
Persona transparency: analyzing the impact of explanations on perceptions of data-driven personas
Computational techniques are becoming more common in persona development. However, users of personas may question the information in persona profiles because they are unsure of how it was created. This problem is especially vexing for data-driven personas because their creation is an opaque algorithmic process. In this research, we analyze the effect of increased transparency–i.e., explanations of how the information in data-driven personas was produced–on user perceptions. We find that higher transparency through these explanations increases the perceived completeness and clarity of the personas. Contrary to our hypothesis, the perceived credibility of the personas decreases with the increased transparency, possibly due to the technical complexity of the persona profiles disrupting the facade of the personas being real people. This finding suggests that explaining the algorithmic process of data-driven persona creation involves a “transparency trade-off”. We also find that the gender of the persona affects the perceptions, with transparency increasing perceived completeness and empathy of the female persona, but not for the male persona. Therefore, transparency may specifically assist in the acceptance of female personas. We provide practical implication for persona creators regarding transparency in persona profiles.info:eu-repo/semantics/acceptedVersio
Dynamics of the topological structures in inhomogeneous media
We present a general review of the dynamics of topological solitons in 1 and
2 dimensions and then discuss some recent work on the scattering of various
solitonic objects (such as kinks and breathers etc) on potential obstructions.Comment: based on the talk given by W.J. Zakrzewski at QTS5. To appear in the
Proceedings in a special issue of Journal of Physics
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