15 research outputs found
EPMA world congress : traditional forum in predictive, preventive and personalised medicine for multi-professional consideration and consolidation
EPMA was created in 2009 as the Forum for Predictive, Preventive and
Personalised Medicine (PPPM). During the 8 years since then, EPMA
meetings – in the form of world congresses and international summits [1-
3] – have traditionally included multi-professional presentations, discussions,
considerations, publications, and consolidation in the field of
PPPM. The EPMA Journal releases over 90% of publications dedicated
to PPPM worldwide, acting as the leading journal in the field. EPMA
currently comprises a network of over 50 countries globally, actively
contributing to the innovative concepts of PPPM. For more information,
please see www.epmanet.eu
The EPMAWorld Congress 2017 in Malta is specifically focused on the
following topics: PPPM in Cancer, PPPM in Neurodegenerative
Neurological Neuropsychiatric Disorders (NNND), PPPM in
Cardiovascular Disease, PPPM in Diabetes Mellitus and related pathologies,
PPPM in Dentistry, Innovative Technologies in PPPM, and
Innovative PPPM Strategies in Healthcare. [Excerpt]peer-reviewe
Predictive markers in cancer patient diagnosis, classification and prediction of therapy outcome using leukaemia as a model
The characterisation of the molecular mechanism of disease
allows classification of patients into subtypes and
potentially identifies specific targets for therapeutic intervention.
Tyrosine kinase mutations are central to specific
targeted therapy. Investigation of kinase deregulation
within particular patient groups, has led to identification
of mutant tyrosine kinases associated with disease progression
and therapy modulation. Biomarker-specific therapies
emerged, taking a leading role in guided-therapy. The
extensive use of the specific kinase inhibitors and the longevity
of the treatment protocols due to the uncertainty of
residual disease, gave rise to new challenges, namely secondary
resistance to therapy. Although there are various
mechanisms of acquired resistance, mutations in the drug
target itself play a dominant role.peer-reviewe
10th Anniversary of the European Association for Predictive, Preventive and Personalised (3P) Medicine - EPMA World Congress Supplement 2020
In 2019, the EPMA celebrated its 10th anniversary at the 5th World Congress in Pilsen, Czech Republic. The history of the International Professional Network dedicated to Predictive, Preventive and Personalised Medicine (PPPM / 3PM) is rich in achievements. Facing the coronavirus COVID-19 pandemic it is getting evident globally that the predictive approach, targeted prevention and personalisation of medical services is the optimal paradigm in healthcare demonstrating the high potential to save lives and to benefit the society as a whole. The EPMA World Congress Supplement 2020 highlights advances in 3P medicine