Genomics and Autism Spectrum Disorder (ASD)

Purpose: To understand the current state of the evidence regarding translation of genetics and genomics into nursing care of children with (ASD)

Autism Spectrum Disorder Symptoms Among Children Enrolled in the Study to Explore Early Development (SEED)

This study examined the phenotypic profiles of children aged 30–68 months in the Study to Explore Early Development (SEED). Children classified as autism spectrum disorder (ASD), developmental delay (DD) with ASD symptoms, DD without ASD symptoms, and population comparison (POP) differed significantly from each other on cognitive, adaptive, behavioral, and social functioning and the presence of parent-reported conditions. Children with ASD and DD with ASD symptoms had mild to severe ASD risk on several measures compared to children with other DD and POP who had little ASD risk across measures. We conclude that children in SEED have varying degrees of ASD impairment and associated deficits. SEED thus provides a valuable sample to explore ASD phenotypes and inform risk factor analyses

The Study to Explore Early Development (SEED): A Multisite Epidemiologic Study of Autism by the Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) Network

The Study to Explore Early Development (SEED), a multisite investigation addressing knowledge gaps in autism phenotype and etiology, aims to: (1) characterize the autism behavioral phenotype and associated developmental, medical, and behavioral conditions and (2) investigate genetic and environmental risks with emphasis on immunologic, hormonal, gastrointestinal, and sociodemographic characteristics. SEED uses a case–control design with population-based ascertainment of children aged 2–5 years with an autism spectrum disorder (ASD) and children in two control groups—one from the general population and one with non-ASD developmental problems. Data from parent-completed questionnaires, interviews, clinical evaluations, biospecimen sampling, and medical record abstraction focus on the prenatal and early postnatal periods. SEED is a valuable resource for testing hypotheses regarding ASD characteristics and causes

Bridges and Barriers to Successful Transitioning as Perceived by Adolescents and Young Adults with Asperger Syndrome

Report and discussion of the results of a thematic content analysis describing how adolescents with Asperger syndrome perceive bridges and barriers to their successful transition to community livin

Chromosomal Microarray Testing in Children with Autism Spectrum Disorders: Clarifying Uncertainties and Improving Understanding

This workshop addresses the utilization of chromosomal microarray (CMA) testing for children with Autism Spectrum Disorder (ASD). We focus on the impact of uncertainties, explore how families understand and make meaning of CMA results, and suggest ways to reduce uncertainties in order to improve understanding and utilization of test results