Genetic Analysis of Blue Marlin (Makaira nigricans) Stock Structure in the Atlantic Ocean

The genetic basis of stock structure of blue marlin (Makaira nigricans Lacepède 1802) in the Atlantic ocean was inferred from analyses of mitochondrial control region sequences. Blue marlin were collected in 1998 from 4 major geographic locations: western North Atlantic, Caribbean Sea, western South Atlantic and eastern Atlantic. Haplotype diversity (h) ranged from 0.99-1.0 and nucleotide sequence diversity (π) ranged from 0.11-0.13 within samples indicating that the control region harbors a significant amount of genetic variation. However, no significant differences were found in the spatial partitioning of genetic variation among the 4 collections; all pairwise ϕST values were negative and were therefore all taken as estimates around a true value of 0. As with previous studies of blue marlin, sequences were comprised of 2 distinct mitochondrial lineages separated by an average of 138 base pairs and ϕST between clades of 0.799 (P \u3c 0.0001). These 2 lineages were present in similar frequencies across sampling locations. Genetic data from this study support management of Atlantic blue marlin as a single, Atlantic-wide stock

Correlation between placental malaria parasitaemia at delivery and infant birth weight in a Nigerian tertiary health centre

Background: Untreated malaria during pregnancy is detrimental to the health and survival of the mother, foetus and neonate due to its great potential to cause maternal anaemia, foetal death and intrauterine growth restriction leading to low birth weight. The foetal complications are due to impaired placental function that results from placental malaria parasitaemia as well as impaired foetal oxygenation from maternal anaemia. This study was conducted to determine the influence of placental malaria parasitaemia on infant birth weight.Methodology: This was a prospective cross-sectional analytical study of 205 parturients recruited consecutively as they presented for delivery at the Federal Medical Centre, Yenagoa. An interviewer-administered questionnaire was used to collect data. After delivery, the neonates were weighed and placental blood was collected for microscopy to detect malaria parasites. Data was analysed using SPSS version 22.Results: The prevalence of placental malaria parasitaemia was 13.7% and Plasmodium falciparum was the only parasite species detected. Placental malaria parasitaemia was associated with a reduction of the mean infant birth weight by 335 grams (P = 0.01).Conclusion: Malaria during pregnancy is still an important public health problem among our obstetric population, with a high prevalence of placental malaria parasitaemia and a significant negative effect on the birth weight of neonates. To enable the developing foetus achieve its full genetic growth potential, pregnant women should be encouraged to register early for antenatal care and utilize all the recommended malaria preventive measures.Keywords: Placenta, malaria infestation, birth weigh

Placental Malaria Parasitization at Delivery: Experience at a Nigerian Tertiary Hospital

Background: In malaria endemic areas, pregnant women are constantly at risk of repeated malaria infestation which if left untreated, poses a significant threat to the health and survival of the mother and her baby. Objective: This study determined the prevalence and risk factors for placental malaria parasitaemia among parturients at the Federal Medical Centre, Yenagoa, Nigeria. Methodology: A prospective cross-sectional analytical study of 205 parturients recruited consecutively at presentation for delivery. An interviewer-administered questionnaire was used to collect data. After delivery, placental blood was collected for microscopy to detect malaria parasites. Data was analysed using SPSS version 22. Results: The prevalence of placental malaria parasitaemia was 13.7%. Maternal age <25 years (P<0.001), low educational status (P = 0.03), low parity (P = 0.03), unbooked status (P < 0.001) and non-use of intermittent preventive treatment (P <0.001) were significantly associated with placental malaria parasitaemia. Receiving three or more doses of sulphadoxine-pyrimethamine for intermittent preventive treatment of malaria in pregnancy was by far, more protective for placental malaria than receiving 2 doses (odds ratio = 0.25). Plasmodium falciparum was the only parasite species detected. Conclusion: Malaria still ravages our obstetric population and the significant contributors include low maternal age, low educational status, low parity, unbooked status and non-use of intermittent preventive treatment in pregnancy. Women should be encouraged to utilize antenatal care. There should be a prompt adoption of the recent WHO recommendations regarding malaria prophylaxis in pregnancy in all obstetric units and the medication should be given as Directly Observed Therapy

Different Ways of Reading, or Just Making the Right Noises?

What does reading look like? Can learning to read be reduced to the acquisition of a set of isolable skills, or proficiency in reading be equated with the independence of the solitary, silent reader of prose fiction? These conceptions of reading and reading development, which figure strongly in educational policy, may appear to be simple common sense. But both ethnographic data and evidence from literary texts suggest that such paradigms offer, at most, a partial and ahistorical picture of reading. An important dimension, neglected in the dominant paradigms, is the irreducibly social quality of reading practices

The effects of graded levels of calorie restriction : III. Impact of short term calorie and protein restriction on mean daily body temperature and torpor use in the C57BL/6 mouse

GRANT SUPPORT This work was supported by BBSRC BB009953/1 awarded to JRS and SEM. PK and CD were funded by the Erasmus exchange programme. JRS, SEM, DD, CG, LC, JJDH, YW, DELP, DL and AD are members of the BBSRC China Partnership Award, BB/J020028/1.Peer reviewedPublisher PD

Singapore's health-care system:key features, challenges, and shifts

Since Singapore became an independent nation in 1965, the development of its health-care system has been underpinned by an emphasis on personal responsibility for health, and active government intervention to ensure access and affordability through targeted subsidies and to reduce unnecessary costs. Singapore is achieving good health outcomes, with a total health expenditure of 4·47% of gross domestic product in 2016. However, the health-care system is contending with increased stress, as reflected in so-called pain points that have led to public concern, including shortages in acute hospital beds and intermediate and long-term care (ILTC) services, and high out-of-pocket payments. The main drivers of these challenges are the rising prevalence of non-communicable diseases and rapid population ageing, limitations in the delivery and organisation of primary care and ILTC, and financial incentives that might inadvertently impede care integration. To address these challenges, Singapore's Ministry of Health implemented a comprehensive set of reforms in 2012 under its Healthcare 2020 Masterplan. These reforms substantially increased the capacity of public hospital beds and ILTC services in the community, expanded subsidies for primary care and long-term care, and introduced a series of financing health-care reforms to strengthen financial protection and coverage. However, it became clear that these measures alone would not address the underlying drivers of system stress in the long term. Instead, the system requires, and is making, much more fundamental changes to its approach. In 2016, the Ministry of Health encapsulated the required shifts in terms of the so-called Three Beyonds—namely, beyond health care to health, beyond hospital to community, and beyond quality to value

Microplastics Detected in Groundwater

Low concentrations of microplastics are present in Illinois’ karst groundwater, according to a preliminary study completed in spring 2018. This is the first time that microplastics have been detected in groundwater. The study was conducted in collaboration with scientists at the Illinois State Geological Survey, Illinois State Water Survey, Loyola University Chicago, and ISTC. Full study results published in Panno, S.V., Kelly, W.R., Scott, J., Zheng, W., McNeish, R.E., Holm, N., Hoellein, T.J. and Baranski, E.L. (2019), Microplastic Contamination in Karst Groundwater Systems. Groundwater, 57: 189-196. doi:10.1111/gwat.12862.League of Women Voters of Jo Daviess County; Illinois State Geological Survey; Illinois State Water Survey; Illinois Sustainable Technology Center (Hazardous Waste Research Fund);. Illinois-Indiana Sea Grant (National Oceanic and Atmospheric Administration ; 074483-15907); National Science Foundation (CAREER 1553835).Ope

Ethnic Differences in Body Fat Deposition and Liver Fat Content in Two UK-Based Cohorts

Objective Differences in the content and distribution of body fat and ectopic lipids may be responsible for ethnic variations in metabolic disease susceptibility. The aim of this study was to examine the ethnic distribution of body fat in two separate UK-based populations. Methods Anthropometry and body composition were assessed in two separate UK cohorts: the Hammersmith cohort and the UK Biobank, both comprising individuals of South Asian descent (SA), individuals of Afro-Caribbean descent (AC), and individuals of European descent (EUR). Regional adipose tissue stores and liver fat were measured by magnetic resonance techniques. Results The Hammersmith cohort (n = 747) had a mean (SD) age of 41.1 (14.5) years (EUR: 374 men, 240 women; SA: 68 men, 22 women; AC: 14 men, 29 women), and the UK Biobank (n = 9,533) had a mean (SD) age of 55.5 (7.5) years (EUR: 4,483 men, 4,873 women; SA: 80 men, 43 women, AC: 31 men, 25 women). Following adjustment for age and BMI, no significant differences in visceral adipose tissue or liver fat were observed between SA and EUR individuals in the either cohort. Conclusions Our data, consistent across two independent UK-based cohorts, present a limited number of ethnic differences in the distribution of body fat depots associated with metabolic disease. These results suggest that the ethnic variation in susceptibility to features of the metabolic syndrome may not arise from differences in body fat

The silting of Lake Carthage, Carthage, Illinois

Cover title.Bibliographical footnotes.Enumeration continues through succeeding title