RATAN-600 7.6-cm Deep Sky Strip Surveys at the Declination of the SS433 Source During the 1980-1999 Period. Data Reduction and the Catalog of Radio Sources in the Right-Ascension Interval 7h < R.A. < 17h

We use two independent methods to reduce the data of the surveys made with RATAN-600 radio telescope at 7.6 cm in 1988-1999 at the declination of the SS433 source. We also reprocess the data of the "Cold" survey (1980-1981). The resulting RCR (RATAN COLD REFINED) catalog contains the right ascensions and fluxes of objects identified with those of the NVSS catalog in the right-ascension interval 7h < R.A. < 17h. We obtain the spectra of the radio sources and determine their spectral indices at 3.94 and 0.5 GHz. The spectra are based on the data from all known catalogs available from the CATS, Vizier, and NED databases, and the flux estimates inferred from the maps of the VLSS and GB6 surveys. For 245 of the 550 objects of the RCR catalog the fluxes are known at two frequencies only: 3.94 GHz (RCR) and 1.4 GHz (NVSS). These are mostly sources with fluxes smaller than 30 mJy. About 65% of these sources have flat or inverse spectra (alpha > -0.5). We analyze the reliability of the results obtained for the entire list of objects and construct the histograms of the spectral indices and fluxes of the sources. Our main conclusion is that all 10-15 mJy objects found in the considered right-ascension interval were already included in the decimeter-wave catalogs.Comment: 26 pages, 18 figure

Study of the Power Beam Pattern of RATAN-600 During the Deep RZF Survey (1998-2003)

This paper proposes a method for constructing an experimental power beam pattern (PB) of RATAN-600 based on the sample of NVSS sources observed in the process of a deep sky survey near local zenith. The data obtained from observations of radio sources at wave 7.6 cm in nine bands of the survey (the 2002 and 2003 sets) are used to construct vertical PB of the telescope at rather large offsets from the central horizontal section of the PB (+/-36'). The experimental PBs obtained using different methods are compared and the root-mean-square deviations of the experimental PB from the corresponding computed PB are determined. The stability of the power beam pattern in its central part (+/-6') during the RATAN-600 Zenith Field (RZF) survey (1998-2003) and the accuracies of the fluxes of the sources observed within the framework of this survey and included into the RZF catalog are estimated.Comment: 15 pages, 17 figure

Correlation properties of the maps of the NVSS survey and WMAP ILC

In this paper we study one-dimensional sections of the maps of WMAP ILC and of the NVSS survey on scale lengths of 0.75, 3, 4.5, and 6.75 degrees and analyze the correlation properties of the sections. On these maps we identify the domains where the absolute value of the correlation coefficient exceeds 0.5. The catalog of such domains is presented. It is shown that the number of the domains agrees with the number of such domains on simulated maps and this fact may be indicative of just statistical agreement of the arrangement of the domains considered.Comment: 8 pages, 2 figure

Catalog of Radio Galaxies with z>0.3. I:Construction of the Sample

The procedure of the construction of a sample of distant ($z>0.3$) radio galaxies using NED, SDSS, and CATS databases for further application in statistical tests is described. The sample is assumed to be cleaned from objects with quasar properties. Primary statistical analysis of the list is performed and the regression dependence of the spectral index on redshift is found.Comment: 9 pages, 6 figures, 2 table

Improving Radiotherapy in Immunosuppressive Microenvironments by Targeting Complement Receptor C5aR1

An immunosuppressive microenvironment causes poor tumor T cell infiltration and is associated with reduced patient overall survival in colorectal cancer. How to improve treatment responses in these tumors is still a challenge. Using an integrated screening approach to identify cancer-specific vulnerabilities, we identified complement receptor C5aR1 as a druggable target, which when inhibited improved radiotherapy, even in tumors displaying immunosuppressive features and poor CD8+ T cell infiltration. While C5aR1 is well-known for its role in the immune compartment, we found that C5aR1 is also robustly expressed on malignant epithelial cells, highlighting potential tumor cell-specific functions. C5aR1 targeting resulted in increased NF-κB-dependent apoptosis specifically in tumors and not normal tissues, indicating that, in malignant cells, C5aR1 primarily regulated cell fate. Collectively, these data revealed that increased complement gene expression is part of the stress response mounted by irradiated tumors and that targeting C5aR1 could improve radiotherapy, even in tumors displaying immunosuppressive features