An example of secondary fault activity along the North Anatolian Fault on the NE Marmara Sea Shelf, NW Turkey

Seismic data on the NE Marmara Sea Shelf indicate that a NNE-SSW-oriented buried basin and ridge system exist on the sub-marine extension of the Paleozoic Rocks delimited by the northern segment of the North Anatolian Fault (NS-NAF), while seismic and multi-beam bathymetric data imply that four NW-SE-oriented strike-slip faults also exist on the shelf area. Seismic data indicate that NW-SE-oriented strike-slip faults are the youngest structures that dissect the basin-ridge system. One of the NW-SE-oriented faults (F1) is aligned with a rupture of the North Anatolian Fault (NAF) cutting the northern slope of the Cinarcik Basin. This observation indicates that these faults have similar characteristics with the NS-NAF along the Marmara Sea. Therefore, they may have a secondary relation to the NAF since the principle deformation zone of the NAF follows the Marmara Trough in that region. The seismic energy recorded on these secondary faults is much less than that on the NAF in the Marmara Sea. These faults may, however, produce a large earthquake in the long term

Expression and production of recombinant proteins from immunodominant E gene regions of bovine viral diarrhoea virus 1 (BVDV-1) Turkish field strains for prophylactic purpose

Since the first description of Bovine Viral Diarrhoea Virus (BVDV) infection, many studies have been performed, and control and eradication programs were developed worldwide. Several studies have been conducted on the presence/prevalence and molecular characterization of BVD viruses in Turkey. However, there is no effective struggle programs for BVDV infection up to now in Turkey. Current study has been conducted for the identification of the E gene region which encodes several immunogenic proteins of BVDV, tested the immunogenicity of the recombinant proteins for possible vaccine production. We focused on the molecular characterization of the E gene region of field pestivirus isolates (n=40) which were obtained in Turkey between 1997 and 2007. Two recombinant proteins, E-ms and E2, were chosen from the E region and expressed in baculovirus vector system. The acquired proteins (approximately 34 kDa for E-ms belonging to BVDV 1-a and 44 kDa for E2 belonging to BVDV 1-l) triggered a humoral immune response in mice. These proteins could represent a good starting material in preparation of vaccines which are indispensable for control and eradication programs of pestivirus infections in Turkey.TUBITAK TOVAG,TurkeyTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [110O915]Animal experiments were conducted follow in the approval of Ankara University Animal Experiments Local Ethical Commitee (Number: 2010-96, 2010-292, 201096-335). This study was supported by TUBITAK TOVAG 110O915, Turkey. The authors thank Alexander Postel for the critisims of designing of primers in this study

The rate of mucosal healing by azathioprine therapy and prediction by artificial systems.

We aimed to assess the effect of azathioprine on mucosal healing in patients with inflammatory bowel diseases (IBD). Artificial neural networks were applied to IBD data for predicting mucosal remission