E.U. paediatric MOG consortium consensus: Part 5 – Treatment of paediatric myelin oligodendrocyte glycoprotein antibody-associated disorders

In recent years, the understanding about the different clinical phenotypes, diagnostic and prognostic factors of myelin oligodendrocyte glycoprotein-antibody-associated disorders (MOGAD) has significantly increased. However, there is still lack of evidence-based treatment protocols for acute attacks and children with a relapsing course of the disease. Currently used acute and maintenance treatment regimens are derived from other demyelinating central nervous system diseases and are mostly centrespecific. Therefore, this part of the Paediatric European Collaborative Consensus attempts to provide recommendations for acute and maintenance therapy based on clinical experience and evidence available from mainly retrospective studies. In the acute attack, intravenous methy

Fanning the flames: women, fashion and politics

In contemporary pop culture, the pursuits regarded as the most frivolous are typically understood to be more feminine in nature than masculine. This collection illustrates how ideas of the popular and the feminine were assumed to be equally naturally intertwined in the eighteenth century, and the ways in which that association facilitates the ongoing trivialization of both

Cette fusion annuelle: cosmopolitanism and identity in Nice, c1815-1860

Between 1815 and 1860, Nice became one of Europe's leading health and leisure resorts, annually hosting an international wintering population of thousands. During a period marked by the rise of the nation-state and national sentiment, Nice was celebrated as ‘une ville cosmopolite’. This article suggests that while geographic, historic and economic factors provided preconditions for cosmopolitanism, Nice's emergence as a peculiarly cosmopolitan town in the first half of the nineteenth century owes much to a combination of forward-looking urban developments and long-established traditions of face-to-face elite sociability, directed and shaped largely by women

Elite women, social politics and the political world of late eighteenth-century England

Political historians have recognized that politics and high society interacted in eighteenth-century England; and most would also recognize the presence of elite women in the social world of politicians. These assumptions have not, however, been subjected to much scrutiny. This article takes the social aspects of politics seriously and aims to provide an introduction to social politics – the management of people and social situations for political ends – and, specifically, to the involvement of women therein. Politics in eighteenth-century England was not just about parliament and politicians; it also had a social dimension. By expanding our understanding of politics to include social politics, we not only reintegrate women into the political world but we also reveal them to have been legitimate political actors, albeit on a non-parliamentary stage, where they played a vital part in creating and sustaining both a uniquely politicized society and the political elite itself. While specific historical circumstances combined in the eighteenth century to facilitate women's socio-political involvement, social politics is limited neither to women nor to the eighteenth century. It has wider implications for historians of all periods and calls into question the way that we conceptualize politics itself. The relationship between the obstinately nebulous arena of social politics and the traditional arena of high politics is ever-changing, but by trivializing the former we limit our ability to understand the latter.</jats:p