On the nature of screening in Voorn-Overbeek type theories

By using the recently formulated Legendre transform approach to the thermodynamics of charged systems, we explore the general form of the screening length in the Voorn-Overbeek type theories, that remains valid also in the cases where the entropy is not given by the ideal gas form as in the Debye-Huckel theory. The screening length consistent with the non-electrostatic terms in the free energy Ansatz for the Flory-Huggins and Voorn-Overbeek type theories, derived from the local curvature properties of the Legendre transform, has distinctly different behavior than the often invoked standard Debye screening length, though it reduces to it in some limiting cases.Comment: 8 pages, 4 figure

Ischemic priapism induced by a fixed drug combination of tamsulosin and tadalafil

Priapism, a persistent erection lasting more than 4 hours, can be caused by various factors, including medications. This case report presents a 23-year-old male who developed ischemic priapism after taking tablet Contiflo-T, a combination of tamsulosin and tadalafil. The patient required multiple interventions, including aspiration and intracavernosal phenylephrine injections, to resolve the condition. The combination of these drugs, which are commonly used for urinary tract symptoms and erectile dysfunction, likely contributed to the priapism by increasing blood flow to the penis and preventing its return to a flaccid state. This case highlights the potential for adverse drug interactions and the importance of careful monitoring when prescribing medications for these conditions

Efficacy and safety of various drugs used for the treatment of nonneurogenic lower urinary tract symptoms in tertiary care hospital

Background: Lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) are common in elder men. Previously surgical treatment was mainstay of treatment of BPH. But now number of drugs alone or combined are clinically used for this disorder. Primary aim was to study the prescribing pattern of different drug therapies and their role in treating LUTS/BPH by evaluating their efficacy and safety in tertiary health care centre.Methods: An observational study including 78 male patients ≥45 years, newly diagnosed with LUTS from April 2014 to May 2015. Patients were followed up every 4 weeks for 3 months after the drug has been prescribed. Efficacy assessment was done on basis of change in IPSS score over 12 weeks. Data was expressed in percentage and Mean ±SD.Results: Mean age of Patients was 64.94 years. Alpha blockers are mainstay prescribed drug either as monotherapy (48.7%) or with 5 alpha reductase inhibitor-dutasteride (38.4%) and with antimuscarinic –Tolterodene (12.8%). Among alpha blockers Tamsulosin (58.97%) was most commonly prescribed, followed by Silodosin (20.5%) and Alfuzosin (20.5%). All drug treatment results in significant improvement with dizziness being the most common adverse event. A subgroup analysis in symptoms was done comparing alpha blockers. All alpha blockers have near about similar efficacy with no significant difference.Conclusions: Alpha blockers are main drugs prescribed in management of LUTS/BPH with near about similar efficacy of all alpha blockers

A Study of Physical Activity Levels and Its Impact on Body Mass Index (BMI) of 8-10 Years Old School Going Children in Mumbai

Introduction: Regular physical activity in childhood and adolescence is important for promoting lifelong health and well-being and preventing various health conditions. The 2008, Physical Activity Guidelines for Americans recommended that children and adolescents aged 6 to 17 years should have 60 minutes (1 hour) or more of moderate and vigorous intensity physical activity each day. Unfortunately, many children and adolescents do not meet the recommendations set forth by the guidelines.&#x0D; Aim: To study the physical activity levels and its impact on body mass index (BMI).&#x0D; Methodology: 420 subjects were selected by purposive random sampling method from 5 schools of Mumbai. Physical activity levels of the samples were assessed through the physical activity questionnaire and the height and weight of all the samples were taken to calculate the BMI.&#x0D; Results: It was observed that 39.5% performed sedentary activities for on an average of 0-1 hr/week. Similarly, 74.2% subjects performed moderate to high intensity activities for an average of 0-1 hr/week. Maximum % of subjects (48%) spent 1-2hr/week in performing sedentary activities whereas, when compared to moderate to high intensity activities maximum % of subjects performed only for 0-1 hr/week. Only 116 subjects met the daily requirements of moderate to high intensity physical activity. A total of 33.2% of samples were observed to be under the three categories of wasting (mild, moderate and severe respectively) as per WHO standards.</jats:p

BIOREMEDIATION OF ARSENIC USING CUCURBITS

Metal pollution has always been a global concern. Arsenic (As) is one of highly toxic metals that threatens million lives worldwide. The present study explores the potential of two cucurbits, Luffa cylindrica M. Roem. and Coccinia indica Wight &amp; Arn. for phytoremediation of arsenic from contaminated water. Arsenic contaminated water with 100 ppb As concentration was treated with different amount of dried fruit biomass of Luffa cylindrica and Coccinia indica. Concentration of As was decreased by 45% after treating 8 g Luffa cylindrica. The As absorption capacity of Luffa cylindrica was found to be higher than Coccinia indica. The work discusses the spontaneous As retention capacity of Luffa cylindrica, which can be good alternative for As remediation for economically underdeveloped rural areas