407 research outputs found
The evolution of a Ku-Band satellite network
The purpose of this study was to undertake the management and development of CTS terminals and time on appropriate Ku-Band satellites was procured. A community of public service users who have readily addressable needs and resources to pay for services on an ad hoc Ku-Band network was developed and a test network for selected users was managed
A redshifted Fe K line from the unusual gamma-ray source PMN J1603-4904
Multiwavelength observations have revealed the highly unusual properties of
the gamma-ray source PMN J1603-4904, which are difficult to reconcile with any
other well established gamma-ray source class. The object is either a very
atypical blazar or compact jet source seen at a larger angle to the line of
sight. In order to determine the physical origin of the high-energy emission
processes in PMN J1603-4904, we study the X-ray spectrum in detail. We
performed quasi-simultaneous X-ray observations with XMM-Newton and Suzaku in
2013 September, resulting in the first high signal-to-noise X-ray spectrum of
this source. The 2-10 keV X-ray spectrum can be well described by an absorbed
power law with an emission line at 5.440.05 keV (observed frame).
Interpreting this feature as a K{\alpha} line from neutral iron, we determine
the redshift of PMN J1603-4904 to be z=0.180.01, corresponding to a
luminosity distance of 87254 Mpc. The detection of a redshifted X-ray
emission line further challenges the original BL Lac classification of PMN
J1603-4904. This result suggests that the source is observed at a larger angle
to the line of sight than expected for blazars, and thus the source would add
to the elusive class of gamma-ray loud misaligned-jet objects, possibly a
{\gamma}-ray bright young radio galaxy.Comment: 5 pages, 1 figure, A&A accepte
The Micro-Arcsecond Scintillation-Induced Variability (MASIV) Survey II: The First Four Epochs
We report on the variability of 443 flat spectrum, compact radio sources
monitored using the VLA for 3 days in 4 epochs at ~ 4 month intervals at 5 GHz
as part of the Micro-Arcsecond Scintillation-Induced Variability (MASIV)
survey. Over half of these sources exhibited 2-10% rms variations on timescales
over 2 days. We analyzed the variations by two independent methods, and find
that the rms variability amplitudes of the sources correlate with the emission
measure in the ionized Interstellar Medium along their respective lines of
sight. We thus link the variations with interstellar scintillation of
components of these sources, with some (unknown) fraction of the total flux
density contained within a compact region of angular diameter in the range
10-50 micro-arcseconds. We also find that the variations decrease for high mean
flux density sources and, most importantly, for high redshift sources. The
decrease in variability is probably due either to an increase in the apparent
diameter of the source, or a decrease in the flux density of the compact
fraction beyond z ~ 2. Here we present a statistical analysis of these results,
and a future paper will the discuss the cosmological implications in detail.Comment: 62 pages, 13 figures. Accepted for publication in the Astrophysical
Journa
Glucagon-like peptide-1 protects against ischemic left ventricular dysfunction during hyperglycemia in patients with coronary artery disease and type 2 diabetes mellitus.
BACKGROUND: Enhancement of myocardial glucose uptake may reduce fatty acid oxidation and improve tolerance to ischemia. Hyperglycemia, in association with hyperinsulinemia, stimulates this metabolic change but may have deleterious effects on left ventricular (LV) function. The incretin hormone, glucagon-like peptide-1 (GLP-1), also has favorable cardiovascular effects, and has emerged as an alternative method of altering myocardial substrate utilization. In patients with coronary artery disease (CAD), we investigated: (1) the effect of a hyperinsulinemic hyperglycemic clamp (HHC) on myocardial performance during dobutamine stress echocardiography (DSE), and (2) whether an infusion of GLP-1(7-36) at the time of HHC protects against ischemic LV dysfunction during DSE in patients with type 2 diabetes mellitus (T2DM). METHODS: In study 1, twelve patients underwent two DSEs with tissue Doppler imaging (TDI)-one during the steady-state phase of a HHC. In study 2, ten patients with T2DM underwent two DSEs with TDI during the steady-state phase of a HHC. GLP-1(7-36) was infused intravenously at 1.2 pmol/kg/min during one of the scans. In both studies, global LV function was assessed by ejection fraction and mitral annular systolic velocity, and regional wall LV function was assessed using peak systolic velocity, strain and strain rate from 12 paired non-apical segments. RESULTS: In study 1, the HHC (compared with control) increased glucose (13.0 ± 1.9 versus 4.8 ± 0.5 mmol/l, p < 0.0001) and insulin (1,212 ± 514 versus 114 ± 47 pmol/l, p = 0.01) concentrations, and reduced FFA levels (249 ± 175 versus 1,001 ± 333 μmol/l, p < 0.0001), but had no net effect on either global or regional LV function. In study 2, GLP-1 enhanced both global (ejection fraction, 77.5 ± 5.0 versus 71.3 ± 4.3%, p = 0.004) and regional (peak systolic strain -18.1 ± 6.6 versus -15.5 ± 5.4%, p < 0.0001) myocardial performance at peak stress and at 30 min recovery. These effects were predominantly driven by a reduction in contractile dysfunction in regions subject to demand ischemia. CONCLUSIONS: In patients with CAD, hyperinsulinemic hyperglycemia has a neutral effect on LV function during DSE. However, GLP-1 at the time of hyperglycemia improves myocardial tolerance to demand ischemia in patients with T2DM. TRIAL REGISTRATION: http://www.isrctn.org . Unique identifier ISRCTN69686930
Heasim and Skyback Simulation Tools and Their Application to the Hitomi Mission
We present an introduction to the heasim multimission observation and skyback background, high-energy pseudo Monte Carlo astrophysical simulation tools. Heasim may be used to accurately and efficiently construct flexible image transport system (FITS) event files for simple or composite sources with a wide range of standard and user-defined spatial, spectral, and temporal characteristics. Skyback is designed to enable users to assess the impact of background discrete and diffuse emission on prospective observations, and skyback output may be directly input into heasim. We present a brief overview of heasim and skyback input, algorithms, usage, and output. We also introduce the sxsbranch tool that computes Hitomi soft X-ray spectrometer resolution grade branching ratios, emphasizing its application to simulations. We include several examples of particular relevance to the Hitomi mission
Interstellar scintillation, AGN physics and the SKA
A large fraction of compact, extragalactic radio sources exhibit rapid variability at centimetre wavelengths as their radio emission is scattered by electron density fluctuations in the interstellar medium of the Galaxy. Next-generation wide-field radio telescopes will have to account for this in forming deep images of the radio sky. Interstellar scintillation offers a unique probe of very small-scale structure in both the ionized interstellar medium and the compact jets of the radio sources themselves. The effective resolution is two orders of magnitude higher than achievable with very long baseline interferometry. The recent Micro-Arcsecond Scintillation-Induced Variability Survey revealed a reduction in ISS at 4.9 GHz with increasing source redshift, implying either an increase in the apparent angular size of high-redshift radio cores beyond that expected due to a cosmological decrease in brightness, or a decrease in the microarcsecond-scale core dominance towards high redshift. The result could be due either to source-intrinsic evolution in the selected sample, or to scatter-broadening in the intergalactic medium
TANAMI - Tracking Active Galactic Nuclei with Austral Milliarcsecond Interferometry
We present a summary of the observation strategy of TANAMI (Tracking Active
Galactic Nuclei with Austral Milliarcsecond Interferometry), a monitoring
program to study the parsec-scale structure and dynamics of relativistic jets
in active galactic nuclei (AGN) of the Southern Hemisphere with the Australian
Long Baseline Array (LBA) and the trans-oceanic antennas Hartebeesthoek, TIGO,
and O'Higgins. TANAMI is focusing on extragalactic sources south of -30 degrees
declination with observations at 8.4 GHz and 22 GHz every ~2 months at
milliarcsecond resolution. The initial TANAMI sample of 43 sources has been
defined before the launch of the Fermi Gamma Ray Space Telescope to include the
most promising candidates for bright gamma-ray emission to be detected with its
Large Area Telescope (LAT). Since November 2008, we have been adding new
sources to the sample, which now includes all known radio- and gamma-ray bright
AGN of the Southern Hemisphere. The combination of VLBI and gamma-ray
observations is crucial to understand the broadband emission characteristics of
AGN and the nature of relativistic jets.Comment: Conference proceedings "2009 Fermi Symposium" eConf Proceedings
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