40 research outputs found

    Coulomb Blockade Fluctuations in Strongly Coupled Quantum Dots

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    Quantum fluctuations of Coulomb blockade are investigated as a function of the coupling to reservoirs in semiconductor quantum dots. We use fluctuations in the distance between peaks ΔN\Delta N apart to characterize both the amplitude and correlation of peak motion. For strong coupling, peak motion is greatly enhanced at low temperature, but does not show an increase in peak-to-peak correlation. These effects can lead to anomalous temperature dependence in the Coulomb valleys, similar to behavior ascribed to Kondo physics.Comment: figures made smaller so download works. Revised, including new data. Related papers at http://www.stanford.edu/group/MarcusLab/grouppubs.htm

    Spin Degeneracy and Conductance Fluctuations in Open Quantum Dots

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    The dependence of mesoscopic conductance fluctuations on parallel magnetic field is used as a probe of spin degeneracy in open GaAs quantum dots. The variance of fluctuations at high parallel field is reduced from the low-field variance (with broken time-reversal symmetry) by factors ranging from roughly two in a 1 square-micron dot at low temperature, to four or greater in 8 square-micron dots. The factor of two is expected for simple Zeeman splitting of spin degenerate channels. A possible explanation for the unexpected larger factors in terms of field-dependent spin orbit scattering is proposed.Comment: Includes new reference to related theoretical work, cond-mat/0010064. Other minor changes. Related papers at http://marcuslab.harvard.ed

    Identification of clinical phenotypes of peripheral involvement in patients with spondyloarthritis, including psoriatic arthritis: a cluster analysis in the worldwide ASAS-PerSpA study

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    OBJECTIVE: To identify clusters of peripheral involvement according to the specific location of peripheral manifestations (ie, arthritis, enthesitis and dactylitis) in patients with spondyloarthritis (SpA) including psoriatic arthritis (PsA), and to evaluate whether these clusters correspond with the clinical diagnosis of a rheumatologist. METHODS: Cross-sectional study with 24 participating countries. Consecutive patients diagnosed by their rheumatologist as PsA, axial SpA or peripheral SpA were enrolled. Four different cluster analyses were conducted: one using information on the specific location from all the peripheral manifestations, and a cluster analysis for each peripheral manifestation, separately. Multiple correspondence analyses and k-means clustering methods were used. Distribution of peripheral manifestations and clinical characteristics were compared across the different clusters. RESULTS: The different cluster analyses performed in the 4465 patients clearly distinguished a predominantly axial phenotype (cluster 1) and a predominantly peripheral phenotype (cluster 2). In the predominantly axial phenotype, hip involvement and lower limb large joint arthritis, heel enthesitis and lack of dactylitis were more prevalent. In the predominantly peripheral phenotype, different subgroups were distinguished based on the type and location of peripheral involvement: a predominantly involvement of upper versus lower limbs joints, a predominantly axial enthesitis versus peripheral enthesitis, and predominantly finger versus toe involvement in dactylitis. A poor agreement between the clusters and the rheumatologist's diagnosis as well as with the classification criteria was found. CONCLUSION: These results suggest the presence of two main phenotypes (predominantly axial and predominantly peripheral) based on the presence and location of the peripheral manifestations

    Statistics of Coulomb Blockade Peak Spacings

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    Distributions of Coulomb blockade peak spacing are reported for large ensembles of both unbroken (magnetic field B = 0) and broken (B 0) time reversal symmetry in GaAs quantum dots. Both distributions are symmetric and roughly gaussian with a width ~ 2-6% of the average spacing, with broad, non-gaussian tails. The distribution is systematically wider at B = 0 by a factor of ~ 1.2 +- 0.1. No even-odd spacing correlations or bimodal structure in the spacing distribution is found, suggesting an absence of spin-degeneracy. There is no observed correlation between peak spacing and peak height.Comment: To appear in PRL; 13 pages, one table, 3 figures; pdf available at http://www-leland.stanford.edu/group/MarcusLab/papers/Patel_peakspacing.pd

    Turkish League Against Rheumatism National recommendations for the management of ankylosing spondylitis [Türkiye romatizma araşti{dotless}rma ve savaş dernegi ankilozan spondilit ulusal tedavi önerileri]

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    Objectives: To develop Turkish League Against Rheumatism (TLAR) National Recommendations for the management of ankylosing spondylitis (AS). Materials and methods: A scientific committee of 25 experts consisting of six rheumatologists and 19 physical medicine and rehabilitation specialists was formed by TLAR. Recommendations were based on the 2006 ASsessment in Ankylosing Spondylitis International Working Group (ASAS)/European League Against Rheumatism (EULAR) recommendations and a systematic review of associated publications between January 2005 and September 2010. A Delphi process was used to develop the recommendations. Twelve major recommendations were constructed for the management of AS. Voting using a numerical rating scale assessed the strength of each recommendation. Results: The 12 recommendations include patient assessment, patient follow-up along with pharmacological and nonpharmacological methods. Some minor additions and changes have been made to the ASAS/EULAR recommendations. All of the recommendations had sufficient strength. Conclusion: National recommendations for the management of AS were developed based on scientific evidence and consensus expert opinion. These recommendations will be updated regularly in accordance with recent developments. ©2011 Turkish League Against Rheumatism. All rights reserved
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