Compared efficacy of preservation solutions in liver transplantation: A long-term graft outcome study from the european liver transplant registry

International audienceBetween 2003 and 2012, 42 869 first liver transplantations performed in Europe with the use of either University of Wisconsin solution (UW; N = 24 562), histidine-tryptophan-ketoglutarate(HTK; N = 8696), Celsior solution (CE; N = 7756) or Institute Georges Lopez preservation solution (IGL-1; N = 1855) preserved grafts. Alternative solutions to the UW were increasingly used during the last decade. Overall, 3-year graft survival was higher with UW, IGL-1 and CE (75%, 75% and 73%, respectively), compared to the HTK (69%) (p 12 h or grafts used for patients with cancer (p < 0.0001). For partial grafts, 3-year graft survival was 89% for IGL-1, 67% for UW, 68% for CE and 64% for HTK (p = 0.009). Multivariate analysis identified HTK as an independent factor of graft loss, with recipient HIV (+), donor age ≥65 years, recipient HCV (+), main disease acute hepatic failure, use of a partial liver graft, recipient age ≥60 years, no identical ABO compatibility, recipient hepatitis B surface antigen (-), TIT ≥ 12 h, male recipient and main disease other than cirrhosis. HTK appears to be an independent risk factor of graft loss. Both UW and IGL-1, and CE to a lesser extent, provides similar results for full size grafts. For partial deceased donor liver grafts, IGL-1 tends to offer the best graft outcome

Le Congrès fondateur du MRP des 25 et 26 novembre 1944

Réunissant des militants chrétiens qui s’étaient engagés contre le nazisme, le MRP, dans son Congrès fondateur (25-26 novembre 1944), se présente comme un mouvement, plus qu’un parti, voulant travailler pour le bien commun de l’ensemble de la société. Il choisit ses dirigeants. Il condamne le libéralisme économique et insiste sur le développement économique et social, bien plus que sur la politique étrangère.Bringing together Christian militants who had engaged against the Nazism, the MRP, in its founder Congress (25- November 26th, 1944), presents itself as a movement, more than a party, wanting to work for the welfare of the whole of the society. It chooses its leaders. He condemns the economic liberalism and insists on economic and social development, much more than on the foreign policy