MONOAMINE OXIDASE A (MAOA), CHILDHOOD TRAUMA, ALCOHOLISM AND AGGRESSION

Women who have experienced childhood sexual abuse (CSA) have an increased risk of alcoholism and antisocial personality disorder (ASPD). Among males, a functional polymorphism (MAOA-LPR, monoamine oxidase A linked polymorphic region) in the promoter region of the monoamine oxidase A gene (MAOA) appears to moderate the effect of childhood maltreatment on antisocial behavior. Our aim was to test whether MAOA-LPR influences the impact of CSA on alcoholism and ASPD in a sample of 291 women, 50% of whom have experienced CSA; we also tested whether haplotypes covering the region where both MAOA and monoamine oxidase B (MAOB) genes are located predict risk of alcoholism and ASPD better than the MAOA-LPR locus alone. Participants included 168 alcoholics (39 with ASPD [antisocial alcoholics]) and 123 controls (no Alcoholics, no ASPD). Antisocial behavior was also modeled as a continuous trait: ASPD symptoms count. The MAOA-LPR low activity allele was associated with alcoholism (p=0.005), particularly antisocial alcoholism (p=0.00009), only among sexually-abused subjects. Sexually-abused women who were homozygous for the low activity allele had higher rates of alcoholism and ASPD, and more ASPD symptoms, than abused women homozygous for the high activity allele. Heterozygous women displayed an intermediate risk pattern. In contrast, there was no relationship between alcoholism/antisocial behavior and MAOA-LPR genotype among non-abused women. The MAOA-LPR low activity allele was found on three different haplotypes. The most abundant MAOA haplotype containing the MAOA-LPR low activity allele was found in excess among alcoholics (p=0.008) and antisocial alcoholics (p=0.001). Finally, a MAOB haplotype, that we termed haplotype C, was significantly associated with alcoholism (p=0.006), and to a lesser extent with antisocial alcoholism (p=0.03). In conclusions, MAOA seems to moderate the impact of childhood trauma on adult psychopathology in females in the same way as previously shown among males. The MAOA-LPR low activity allele appears to confer increased vulnerability to the adverse psychosocial consequences of CSA. Haplotype-based analysis of the MAOA gene appeared to strengthen the association, as compared to the MAOA-LPR locus alone. A MAOB haplotype was associated with alcoholism independently from ASPD

Observations of the post shock break-out emission of SN 2011dh with XMM-Newton

After the occurrence of the type cIIb SN 2011dh in the nearby spiral galaxy M 51 numerous observations were performed with different telescopes in various bands ranging from radio to gamma-rays. We analysed the XMM-Newton and Swift observations taken 3 to 30 days after the SN explosion to study the X-ray spectrum of SN 2011dh. We extracted spectra from the XMM-Newton observations, which took place ~7 and 11 days after the SN. In addition, we created integrated Swift/XRT spectra of 3 to 10 days and 11 to 30 days. The spectra are well fitted with a power-law spectrum absorbed with Galactic foreground absorption. In addition, we find a harder spectral component in the first XMM-Newton spectrum taken at t ~ 7 d. This component is also detected in the first Swift spectrum of t = 3 - 10 d. While the persistent power-law component can be explained as inverse Compton emission from radio synchrotron emitting electrons, the harder component is most likely bremsstrahlung emission from the shocked stellar wind. Therefore, the harder X-ray emission that fades away after t ~ 10 d can be interpreted as emission from the shocked circumstellar wind of SN 2011dh.Comment: Accepted for publication as a Research Note in Astronomy and Astrophysic

Searching for coherent pulsations in ultraluminous X-ray sources

Luminosities of ultraluminous X-ray sources (ULXs) are uncomfortably large if compared to the Eddington limit for isotropic accretion onto stellar-mass object. Most often either supercritical accretion onto stellar mass black hole or accretion onto intermediate mass black holes is invoked the high luminosities of ULXs. However, the recent discovery of coherent pulsations from M82 ULX with NuSTAR showed that another scenario implying accretion onto a magnetized neutron star is possible for ULXs. Motivated by this discovery, we re-visited the available XMM-Newton archival observations of several bright ULXs with a targeted search for pulsations to check whether accreting neutron stars might power other ULXs as well. We have found no evidence for significant coherent pulsations in any of the sources including the M82 ULX. We provide upper limits for the amplitude of possibly undetected pulsed signal for the sources in the sample.Comment: 2 pages, 1 figure, submitted to A&

Population of the Galactic X-ray binaries and eRosita

The population of the Galactic X-ray binaries has been mostly probed with moderately sensitive hard X-ray surveys so far. The eRosita mission will provide, for the first time a sensitive all-sky X-ray survey in the 2-10 keV energy range, where the X-ray binaries emit most of the flux and discover the still unobserved low-luminosity population of these objects. In this paper, we briefly review the current constraints for the X-ray luminosity functions of high- and low-mass X-ray binaries and present our own analysis based the INTEGRAL 9-year Galactic survey, which yields improved constraints. Based on these results, we estimate the number of new XRBs to be detected in the eRosita all-sky surveyComment: accepted for publication in A&

An easy-To-use method for assessing nitrate contamination susceptibility in groundwater

This research presents a methodology for assessing nitrate contamination susceptibility in groundwater using thematic maps, derived mainly from the land use map and from statistical data available at national/regional institutes of statistics (especially demographic and environmental data). The methodology was applied in a large area of southern Italy encompassing 4 alluvial and volcanic groundwater bodies, with high concentrations of NO3. The Potential Nitrate Contamination is believed to derive from three sources: agricultural, urban, and periurban. The first one is related to the use of fertilizers. For this reason the land use map was reclassified on the basis of the crop requirements in terms of fertilizers to obtain the Agricultural Potential Nitrate Contamination (APNC) map.The urban source considers leakages from the sewage network and, consequently, it depends on the anthropogenic pressure, expressed by the population density, particularly concentrated in the urbanized areas (Urban Potential Nitrate Contamination (UPNC)map). The periurban sources include unsewered areas, especially present in the periurban context, where illegal sewage connections coexist with on-site sewage disposal (cesspools, septic tanks, and pit latrines) (Periurban Potential Nitrate Contamination (PuPNC) map). The Potential Nitrate Contamination (PNC) map is produced by overlaying the APNC, UPNC, and PuPNC maps. The map combination process is straightforward, being an algebraic combination: the output values are the arithmetic average of the input values. The final pollution susceptibility (RISK) map is obtained by combining the PNC map with the groundwater contamination vulnerability (GwVu) map. The methodology, successfully applied in the study area with a relatively good correlation between the nitrate contamination susceptibility map and the nitrate distribution in groundwater, appears to be effective and have a significant potential for being applied worldwide

Swift monitoring of IGR J16418-4532

We report on the Swift observations of the candidate supergiant fast X-ray transient (SFXT) IGR J16418-4532, which has an orbital period of ~3.7 d. Our monitoring, for a total of ~43 ks, spans over three orbits and represents the most intense and complete sampling along the orbital period of the light curve of this source. If one assumes a circular orbit, the X-ray emission from this source can be explained by accretion from a spherically symmetric clumpy wind from a blue supergiant, composed of clumps with different masses, ranging from ~5x10^16 g to 10^21g.Comment: 4 pages; Proceedings, 5th International Symposium on High-Energy Gamma-Ray Astronomy, (Gamma2012) Heidelberg, Germany, July 9-13th, 201

XMM-Newton observation of the interacting galaxies NGC1512 and NGC1510

The galaxy NGC1512 is interacting with the smaller galaxy NGC1510 and shows a peculiar morphology, characterised by two extended arms immersed in an HI disc whose size is about four times larger than the optical diameter of NGC1512. For the first time we performed a deep X-ray observation of the galaxies NGC1512 and NGC1510 with XMM-Newton to gain information on the population of X-ray sources and diffuse emission in a system of interacting galaxies. We identified and classified the sources detected in the XMM-Newton field of view by means of spectral analysis, hardness-ratios calculated with a Bayesian method, X-ray variability, and cross-correlations with catalogues in optical, infrared, and radio wavelengths. We also made use of archival Swift (X-ray) and Australia Telescope Compact Array (radio) data to better constrain the nature of the sources detected with XMM-Newton. We detected 106 sources in the energy range of 0.2-12 keV, out of which 15 are located within the D_25 regions of NGC1512 and NGC1510 and at least six sources coincide with the extended arms. We identified and classified six background objects and six foreground stars. We discussed the nature of a source within the D_25 ellipse of NGC1512, whose properties indicate a quasi-stellar object or an intermediate ultra-luminous X-ray source. Taking into account the contribution of low-mass X-ray binaries and active galactic nuclei, the number of high-mass X-ray binaries detected within the D_25 region of NGC1512 is consistent with the star formation rate obtained in previous works based on radio, infrared optical, and UV wavelengths. We detected diffuse X-ray emission from the interior region of NGC1512 with a plasma temperature of kT=0.68(0.31-0.87) keV and a 0.3-10 keV X-ray luminosity of 1.3E38 erg/s, after correcting for unresolved discrete sources.Comment: Accepted for publication in Astronomy and Astrophysics. 20 pages. Appendix B will be published electronically onl

Exploring the role of X-ray reprocessing and irradiation in the anomalous bright optical outbursts of A0538-66

In 1981, the Be/X-ray binary (Be/XRB) A0538-66 showed outbursts characterized by high peak luminosities in the X-ray and optical bands. The optical outbursts were qualitatively explained as X-ray reprocessing in a gas cloud surrounding the binary system. Since then, further important information about A0538-66 have been obtained, and sophisticated photoionization codes have been developed to calculate the radiation emerging from a gas nebula illuminated by a central X-ray source. In the light of the new information and tools available, we studied again the enhanced optical emission displayed by A0538-66 to understand the mechanisms responsible for these unique events among the class of Be/XRBs. We performed about 10^5 simulations of a gas envelope photoionized by an X-ray source. We assumed for the shape of the gas cloud either a sphere or a circumstellar disc observed edge-on. We studied the effects of varying the main properties of the envelope and the influence of different input X-ray spectra on the optical/UV emission emerging from the photoionized cloud. We compared the computed spectra with the IUE spectrum and photometric UBV measurements obtained during the outburst of 29 April 1981. We also explored the role played by the X-ray heating of the surface of the donor star irradiated by the X-ray emission of the neutron star (NS). We found that reprocessing in a spherical cloud with a shallow radial density distribution can reproduce the optical/UV emission. To our knowledge, this configuration has never been observed either in A0538-66 during other epochs or in other Be/XRBs. We found, contrary to the case of most other Be/XRBs, that the optical/UV radiation produced by the X-ray heating of the surface of the donor star irradiated by the NS is non-negligible, due to the particular orbital parameters of this system that bring the NS very close to its companion.Comment: Accepted for publication in Astronomy & Astrophysics. Abstract abridged to meet arXiv requirement

Semiconductor devices for entangled photon pair generation: a review

Entanglement is one of the most fascinating properties of quantum mechanical systems; when two particles are entangled the measurement of the properties of one of the two allows to instantaneously know the properties of the other, whatever the distance separating them. In parallel with fundamental research on the foundations of quantum mechanics performed on complex experimental set-ups, we assist today to a bourgeoning of quantum information technologies bound to exploit entanglement for a large variety of applications such as secure communications, metrology and computation. Among the different physical systems under investigation, those involving photonic components are likely to play a central role and in this context semiconductor materials exhibit a huge potential in terms of integration of several quantum components in miniature chips. In this article we review the recent progress in the development of semiconductor devices emitting entangled photons. We will present the physical processes allowing to generate entanglement and the tools to characterize it; we will give an overview of major recent results of the last years and highlight perspectives for future developments.Comment: Review article (58 pages, 25 figures, 240 references